Volume 24 Issue 6
Jun.  2026
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Article Navigation >  Chinese Journal of General Practice  > 2026  >  24(6): 1081-1084
CHEN Yanna, GU Wensha, ZHOU Yue, HU Changjun, CAO Huimin, SHI Min. A case report of pseudohypoparathyroidism with epilepsy as the initial symptom[J]. Chinese Journal of General Practice, 2026, 24(6): 1081-1084. doi: 10.16766/j.cnki.issn.1674-4152.004559
Citation: CHEN Yanna, GU Wensha, ZHOU Yue, HU Changjun, CAO Huimin, SHI Min. A case report of pseudohypoparathyroidism with epilepsy as the initial symptom[J]. Chinese Journal of General Practice, 2026, 24(6): 1081-1084. doi: 10.16766/j.cnki.issn.1674-4152.004559
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A case report of pseudohypoparathyroidism with epilepsy as the initial symptom

doi: 10.16766/j.cnki.issn.1674-4152.004559

  • Department of Endocrinology, the Affiliated Huai'an No.1 People's Hospital of Nanjing Medical University, Huai'an, Jiangsu 223000, China

  • Received Date: 2025-06-22
    Available Online: 2026-11-10
    Abstract
  • Pseudohypoparathyroidism (PHP) is a rare inherited disease, of which biochemical parameters show low blood calcium, high blood phosphorus, and high parathyroid hormone. The clinical manifestations of PHP are significantly heterogeneous. These PHP patients with epilepsy as the first symptom and without albright hereditary osteodystrophy (AHO) are easily misdiagnosed. This article selected one case of PHP with epilepsy from the Department of Endocrinology in the Huai'an No.1 People's Hospital. Its clinical data, laboratory tests, imaging examinations, genetic testing results, and follow-up were analyzed in combination with relevant literature at home and abroad. We aimed to explore the clinical characteristics and management strategies of PHP in order to improve the diagnostic and management abilities of clinical doctors for this disease.

     

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