Volume 24 Issue 6
Jun.  2026
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Article Navigation >  Chinese Journal of General Practice  > 2026  >  24(6): 1055-1058
LIANG Shunyu, MA Xia, JIN Aiai, RAO Jie, ZHANG Junling, WU Tao. The effect of empowering nursing on compliance with dual induction therapy in patients with acute promyelocytic leukemia[J]. Chinese Journal of General Practice, 2026, 24(6): 1055-1058. doi: 10.16766/j.cnki.issn.1674-4152.004552
Citation: LIANG Shunyu, MA Xia, JIN Aiai, RAO Jie, ZHANG Junling, WU Tao. The effect of empowering nursing on compliance with dual induction therapy in patients with acute promyelocytic leukemia[J]. Chinese Journal of General Practice, 2026, 24(6): 1055-1058. doi: 10.16766/j.cnki.issn.1674-4152.004552
shu

The effect of empowering nursing on compliance with dual induction therapy in patients with acute promyelocytic leukemia

doi: 10.16766/j.cnki.issn.1674-4152.004552

  • Department of Hematology, 940th Hospital, Joint Logistics Support Force, Lanzhou, Gansu 730500, China

Funds:

 23JRRA534

  • Received Date: 2025-06-16
    Available Online: 2026-11-10
    Abstract
  •   Objective  To explore the clinical value of empowerment nursing (EN) for patients with acute promyelocytic leukemia (APL) undergoing dual induction therapy, as well as its impact on patients' empowerment level, treatment compliance, and complications.  Methods  A total of 100 APL patients admitted to the Department of Hematology, 940th Hospital of the Joint Logistics Support Force of Chinese People's Liberation Army from August 2023 to March 2025 were enrolled and randomly divided into a control group (n=50, routine nursing) and an experimental group (n=50, routine nursing+EN) using a random number table method. Empowerment levels, treatment compliance, remission of disease, and complications were compared between the two groups.  Results  The empowerment level of the experimental group was superior to that of the control group (Z=3.960, P < 0.001). After 8 months of intervention, the scores for medication, diet, environment, psychological status, and overall compliance in both groups were significantly higher than those before the intervention, and these scores, as well as the total scores, were significantly higher in the experimental group (P < 0.05). The level of peripheral white blood cell count (WBC) was significantly higher than that in control group (P < 0.05), while the proportion of promyelocyte was significantly lower (P < 0.05). The incidence of major complications such as hemorrhage, infection, differentiation syndrome (DS) and central nervous system leukemia (CNSL) in the experimental group was significantly lower than those in the control group (P < 0.05).  Conclusion  EN has positive significance in improving compliance with dual induction therapy in APL patients, decreasinging the proportion of promyelocytes, reducing the incidence of major complications during treatment.

     

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