Volume 24 Issue 6
Jun.  2026
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Article Navigation >  Chinese Journal of General Practice  > 2026  >  24(6): 1047-1050
REN Li, GE Jiaoyu, FU Huanying, XIE Mengjiao, WANG Shanshan. Construction of a preoperative nutrition management plan for patients with gastric cancer conversion therapy based on evidence summary[J]. Chinese Journal of General Practice, 2026, 24(6): 1047-1050. doi: 10.16766/j.cnki.issn.1674-4152.004550
Citation: REN Li, GE Jiaoyu, FU Huanying, XIE Mengjiao, WANG Shanshan. Construction of a preoperative nutrition management plan for patients with gastric cancer conversion therapy based on evidence summary[J]. Chinese Journal of General Practice, 2026, 24(6): 1047-1050. doi: 10.16766/j.cnki.issn.1674-4152.004550
shu

Construction of a preoperative nutrition management plan for patients with gastric cancer conversion therapy based on evidence summary

doi: 10.16766/j.cnki.issn.1674-4152.004550

  • Department of Gastric Surgery, Zhejiang Cancer Hospital, Hangzhou, Zhejiang 330100, China

Funds:

 2026ZL0213

 2025HY0215

 2026ZL0219

  • Received Date: 2025-09-11
    Available Online: 2026-11-10
    Abstract
  •   Objective  Systematically integrate evidence-based medical findings in the field of preoperative nutritional management for patients undergoing neoadjuvant therapy for gastric cancer, and to develop a scientific and standardized implementation plan for preoperative nutritional management.  Methods  By systematically searching domestic and foreign authoritative databases and combining with scientific literature quality evaluation and analysis methods, a preliminary preoperative nutrition management plan for gastric cancer patients undergoing conversion therapy was formulated. From October to December 2024, the Delphi method was used to conduct two rounds of letter consultation with 14 experts. According to expert feedback, the items of the plan were revised and optimized, and the latest evidence-based evidence was integrated to finally form a perfect preoperative nutrition management plan.  Results  Patients with gastric cancer are often accompanied by severe malnutrition and cachexia. The implementation of standardized preoperative nutritional support can significantly improve the clinical prognosis of patients with gastric cancer conversion therapy, not only improve serum protein and hemoglobin levels, strengthen the tolerance of conversion therapy such as chemotherapy and radiotherapy, but also reduce the incidence of adverse reactions such as nausea and vomiting from 70% to 40%-50%. The interruption of treatment due to adverse reactions was reduced to ensure the continuity of treatment. In addition, nutritional intervention can improve the tumor response rate, prolong the survival of patients, and reduce the prolonged hospitalization and medical costs caused by malnutrition. Through two rounds of expert consultation (the recovery rates were 93.3% and 100.0%, respectively), a preoperative nutrition management plan for patients with gastric cancer conversion therapy was constructed, including 7 first-level items and 36 second-level items. The authority coefficient was 0.825, and the Kendall harmony coefficients were 0.259 and 0.530, respectively (P < 0.001). The coefficient of variation of each item ranged from 0 to 0.175.  Conclusion  The evidence-based preoperative nutrition management plan for patients with gastric cancer conversion therapy is scientific and clinical practical, which can provide a reference for the practice of preoperative nutrition management for patients with gastric cancer conversion therapy in the future.

     

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