Study on the characteristics, etiology, diagnosis and treatment of fatigue patients in general practice wards of general hospitals

XU Linlin; CHEN Mingmin; REN Jingjing; MA Yundi

doi:10.16766/j.cnki.issn.1674-4152.004548

Volume 24 Issue 6

Jun. 2026

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Article Navigation > Chinese Journal of General Practice > 2026 > 24(6): 1037-1041

XU Linlin, CHEN Mingmin, REN Jingjing, MA Yundi. Study on the characteristics, etiology, diagnosis and treatment of fatigue patients in general practice wards of general hospitals[J]. Chinese Journal of General Practice, 2026, 24(6): 1037-1041. doi: 10.16766/j.cnki.issn.1674-4152.004548

Citation:

XU Linlin, CHEN Mingmin, REN Jingjing, MA Yundi. Study on the characteristics, etiology, diagnosis and treatment of fatigue patients in general practice wards of general hospitals[J]. Chinese Journal of General Practice, 2026, 24(6): 1037-1041. doi: 10.16766/j.cnki.issn.1674-4152.004548

Citation:

XU Linlin, CHEN Mingmin, REN Jingjing, MA Yundi. Study on the characteristics, etiology, diagnosis and treatment of fatigue patients in general practice wards of general hospitals[J]. Chinese Journal of General Practice, 2026, 24(6): 1037-1041. doi: 10.16766/j.cnki.issn.1674-4152.004548

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Study on the characteristics, etiology, diagnosis and treatment of fatigue patients in general practice wards of general hospitals

doi: 10.16766/j.cnki.issn.1674-4152.004548

XU Linlin^{1, 2}
, CHEN Mingmin¹
, REN Jingjing^{1
,
,}
, MA Yundi¹

1.
Department of General Practice, the First Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, Zhejiang 310003, China

Funds:

72274169

Received Date: 2025-07-15
Available Online: 2026-11-10

Abstract

Abstract

Objective To analyze the clinical characteristics, etiology, and diagnosis-treatment outcomes of patients admitted with "fatigue of unknown origin" in the general practice ward of a general hospital, and to provide references for enhancing the diagnostic and management capabilities of general practitioners. Methods A retrospective study was conducted on 289 patients with "fatigue of unknown origin" as the primary diagnosis in the General Practice Ward of the First Affiliated Hospital of Zhejiang University School of Medicine from October 31, 2022, to December 31, 2024. Data on demographics, predisposing factors, accompanying symptoms, final etiological diagnoses, and treatment outcomes were collected and statistically analyzed. Results Among the 289 patients, 175 (60.55%) were female and 114 (39.45%) were male, with a mean age of (56.37±12.28) years. The most common predisposing factors were sleep deprivation (139 cases, 48.10%) and nutritional issues (93 cases, 32.18%). The top three etiological categories were mental disorders (97 cases, 33.56%), digestive system diseases (70 cases, 24.22%), and endocrine system diseases (62 cases, 21.45%). Regarding treatment outcomes, a definitive plan was established within the general practice ward for 106 patients (36.68%), 82 patients (28.37%) required referral to specialists, and no definitive plan was established for 101 patients (34.95%). Conclusion Patients with fatigue of unknown origin in the general practice ward of a general hospital are predominantly middle-aged and elderly females. Sleep deprivation and nutritional issues are the main predisposing factors, while mental disorders, digestive, and endocrine system diseases are the leading causes. General practitioners need to enhance competencies in differential diagnosis, comorbidity management, psychological assessment and intervention, and multidisciplinary collaboration and referral to improve patient outcomes.
- General practice,
- General hospital,
- Fatigue,
- Medically unspecified disease

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References

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Study on the characteristics, etiology, diagnosis and treatment of fatigue patients in general practice wards of general hospitals

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