Volume 24 Issue 6
Jun.  2026
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XU Xiaoyan, LI Jian, FENG Jiong, CHENG Dong, ZHOU Chunting, FANG Lingli. Clinical efficacy of medicinal cake fire dragon moxibustion in the treatment of rheumatoid knee arthritis of the wind-cold-dampness syndrome type[J]. Chinese Journal of General Practice, 2026, 24(6): 968-971. doi: 10.16766/j.cnki.issn.1674-4152.004532
Citation: XU Xiaoyan, LI Jian, FENG Jiong, CHENG Dong, ZHOU Chunting, FANG Lingli. Clinical efficacy of medicinal cake fire dragon moxibustion in the treatment of rheumatoid knee arthritis of the wind-cold-dampness syndrome type[J]. Chinese Journal of General Practice, 2026, 24(6): 968-971. doi: 10.16766/j.cnki.issn.1674-4152.004532

Clinical efficacy of medicinal cake fire dragon moxibustion in the treatment of rheumatoid knee arthritis of the wind-cold-dampness syndrome type

doi: 10.16766/j.cnki.issn.1674-4152.004532
Funds:

 2023-3-139

 LGD21H090007

  • Received Date: 2026-01-08
    Available Online: 2026-11-10
  •   Objective  There is a lack of specific treatments for rheumatoid arthritis of the knee. This study aimed to evaluate the clinical efficacy of fire dragon moxibustion with medicinal cake, a traditional Chinese medicine therapy, for patients with wind cold damp obstruction type rheumatoid knee arthritis.  Methods  A total of 108 patients with wind cold damp obstruction type rheumatoid knee arthritis admitted to the Department of Rheumatology and Immunology, Jinhua Hospital of Chinese Medicine, from June 2023 to October 2025 were enrolled. Patients were randomly divided into a control group and a trial group (n=54 each) using a random number table. The control group received celecoxib, and the trial group received fire dragon moxibustion with medicinal cake for 4 weeks. Traditional Chinese medicine (TCM) syndrome scores, visual analogue scale (VAS) pain scores, Lysholm knee scores, laboratory parameters including erythrocyte sedimentation rate (ESR), C reactive protein (CRP), rheumatoid factor (RF), tumor necrosis factor-α (TNF-α), and musculoskeletal ultrasound findings were compared between the two groups. Clinical efficacy and safety were evaluated.  Results  After 4 weeks of treatment, TCM syndrome scores and VAS scores decreased in both groups compared with baseline, while Lysholm scores increased (P < 0.05). The trial group showed significantly lower VAS scores (1.65±0.43 vs. 2.70±0.68), and higher Lysholm scores (82.70±6.24 vs. 78.19±6.07) than the control group (P < 0.05). Levels of ESR, CRP, RF, and TNF α decreased in both groups after treatment, with significantly lower values in the trial group (P < 0.05). Musculoskeletal ultrasound findings, including synovial thickness, suprapatellar effusion thickness, and synovial blood flow score, improved significantly in both groups, with better outcomes in the trial group (P < 0.05). The TCM syndrome efficacy rate was significantly higher in the trial group (P < 0.05), and no serious adverse events occurred in either group.  Conclusion  Fire dragon moxibustion with medicinal cake can effectively relieve clinical symptoms, reduce immune inflammatory responses, alleviate synovial inflammation, and improve knee function in patients with wind cold damp obstruction type rheumatoid knee arthritis. It demonstrates significant clinical efficacy and good safety.

     

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  • [1]
    ZHANG A R, CHENG Q H, YANG Y Z, et al. Meta-analysis of outcomes after total knee arthroplasty in patients with rheumatoid arthritis and osteoarthritis[J]. Asian J Surg, 2024, 47(1): 43-54. doi: 10.1016/j.asjsur.2023.09.015
    [2]
    魏爽, 王蕊, 李欣宇, 等. 类风湿关节炎中的免疫与代谢研究及中医药治疗进展[J]. 天津中医药大学学报, 2025, 44(4): 358-365.

    Wei S, Wang R, Li X Y, et al. Research progress on immunity and metabolism in rheumatoid arthritis and treatment with traditional Chinese medicine[J]. Journal of Tianjin University of Traditional Chinese Medicine, 2025, 44(4): 358-365.
    [3]
    陈君洁, 孙玥, 李明, 等. 正清风痛宁片治疗风寒湿痹型类风湿关节炎的多中心临床疗效[J]. 中国实验方剂学杂志, 2024, 30(16): 132-139.

    Chen J J, Sun Y, Li M, et al. Multicenter clinical efficacy of Zhengqing Fengtongning Tablets in treating rheumatoid arthritis of wind-cold-dampness obstruction type[J]. Chinese Journal of Experimental Traditional Medical Formulae, 2024, 30(16): 132-139.
    [4]
    董逸飞, 时素华, 杨颖, 等. 从督脉理论探析督脉灸治疗骨质疏松性脊柱骨折[J]. 陕西中医, 2025, 46(6): 791-794.

    Dong Y F, Shi S H, Yang Y, et al. Analysis on Governor Vessel moxibustion in the treatment of osteoporotic spinal fracture based on Governor Vessel theory[J]. Shaanxi Journal of Traditional Chinese Medicine, 2025, 46(6): 791-794.
    [5]
    中华医学会风湿病学分会. 2018中国类风湿关节炎诊疗指南[J]. 中华内科杂志, 2018, 57(4): 242-251.

    Chinese Medical Association Rheumatology Branch. 2018 Chinese guidelines for the diagnosis and treatment of rheumatoid arthritis[J]. Chinese Journal of Internal Medicine, 2018, 57(4): 242-251.
    [6]
    姜泉, 王海隆, 巩勋, 等. 类风湿关节炎病证结合诊疗指南[J]. 中国中医骨伤科杂志, 2020, 28(4): 86-88.

    Jiang Q, Wang H L, Gong X, et al. Guidelines for the diagnosis and treatment of rheumatoid arthritis with integrated traditional Chinese and Western medicine[J]. Chinese Journal of Traditional Chinese Medicine Orthopedics and Traumatology, 2020, 28(4): 86-88.
    [7]
    郑筱萸. 中药新药临床研究指导原则: 试行[M]. 北京: 中国医药科技出版社, 2002: 73-77.

    Zheng X Y. Guiding Principles for Clinical Research of New Drugs of Traditional Chinese Medicine (Trial)[M]. Beijing: China Medical Science Press, 2002: 73-77.
    [8]
    彭晓松, 曲小雨, 刘培林. 肌肉骨骼超声对膝关节滑膜炎的诊断分析[J]. 影像科学与光化学, 2022, 40(4): 942-946.

    Peng X S, Qu X Y, Liu P L. Diagnostic analysis of musculoskeletal ultrasound in knee synovitis[J]. Imaging Science and Photochemistry, 2022, 40(4): 942-946.
    [9]
    王小燕, 南雅炫, 马吴丹, 等. 肌骨超声特征评分对老年类风湿关节炎患者疾病活动度的评估价值[J]. 中国老年学杂志, 2025, 45(10): 2368-2371.

    Wang X Y, Nan Y X, Ma W D, et al. Value of musculoskeletal ultrasound characteristic score in evaluating disease activity in elderly patients with rheumatoid arthritis[J]. Chinese Journal of Gerontology, 2025, 45(10): 2368-2371.
    [10]
    王涛, 李志军. 类风湿关节炎的诊断与治疗[J]. 中华全科医学, 2020, 18(2): 170-171.

    Wang T, Li Z J. Diagnosis and treatment of rheumatoid arthritis[J]. Chinese Journal of General Practice, 2020, 18(2): 170-171.
    [11]
    张晓东, 王婕. 赵绍琴教授焦树德教授治疗类风湿关节炎用药经验[J]. 光明中医, 2024, 39(8): 1533-1536.

    Zhang X D, Wang J. Medication experience of Professors Zhao Shaoqin and Jiao Shude in treating rheumatoid arthritis[J]. Guangming Journal of Chinese Medicine, 2024, 39(8): 1533-1536.
    [12]
    杨煜辰, 姜泉, 巩勋, 等. 1 191例寒湿痹阻证类风湿关节炎患者的证候演变特点及相关性分析[J]. 中国中医基础医学杂志, 2024, 30(6): 970-974.

    Yang Y C, Jiang Q, Gong X, et al. Characteristics of syndrome evolution and correlation analysis in 1 191 patients with rheumatoid arthritis of cold-dampness obstruction syndrome[J]. Chinese Journal of Basic Medicine in Traditional Chinese Medicine, 2024, 30(6): 970-974.
    [13]
    吴东明, 董金莉, 谈平. 谈平教授治疗类风湿关节炎临床经验[J]. 中国医药导报, 2024, 21(7): 139-143.

    Wu D M, Dong J L, Tan P. Clinical experience of Professor Tan Ping in treating rheumatoid arthritis[J]. China Medical Herald, 2024, 21(7): 139-143.
    [14]
    陈雪猛, 王勇, 吴维. 基于网络药理学分析桂枝治疗类风湿关节炎的作用机制[J]. 中南医学科学杂志, 2023, 51(1): 45-48.

    Chen X M, Wang Y, Wu W. Analysis on mechanism of Ramulus Cinnamomi in treating rheumatoid arthritis based on network pharmacology[J]. Journal of Xiangnan University(Medical Sciences), 2023, 51(1): 45-48.
    [15]
    白翠慧, 侯国栋, 关永霞, 等. 独活化学成分及药理作用研究进展[J]. 中华中医药学刊, 2025, 43(10): 129-144.

    Bai C H, Hou G D, Guan Y X, et al. Research progress on chemical constituents and pharmacological effects of Radix Angelicae Pubescentis[J]. Chinese Archives of Traditional Chinese Medicine, 2025, 43(10): 129-144.
    [16]
    张庆, 黄娟, 邵瑜, 等. 基于扶阳通痹理论的火龙灸疗法治疗风寒湿痹型类风湿关节炎疗效观察[J]. 现代中西医结合杂志, 2025, 34(8): 1099-1103.

    Zhang Q, Huang J, Shao Y, et al. Observation on curative effect of fire dragon moxibustion based on the theory of strengthening yang and unblocking bi-syndrome in treating rheumatoid arthritis of wind-cold-dampness obstruction type[J]. Modern Journal of Integrated Traditional Chinese and Western Medicine, 2025, 34(8): 1099-1103.
    [17]
    梁铭坤, 段晓荣, 刘彩娇, 等. 基于数据挖掘分析针灸治疗类风湿关节炎选穴规律[J]. 中国中医药图书情报杂志, 2025, 49(4): 83-89.

    Liang M K, Duan X R, Liu C J, et al. Analysis on acupoint selection rules of acupuncture and moxibustion for rheumatoid arthritis based on data mining[J]. Chinese Journal of Traditional Chinese Medicine Library and Information, 2025, 49(4): 83-89.
    [18]
    单玉辉, 李阳, 乔学能, 等. 类风湿性膝关节炎肌骨超声特征与炎症因子的关系及在疗效评估中的作用[J]. 新疆医科大学学报, 2025, 48(7): 957-962, 967.

    Shan Y H, Li Y, Qiao X N, et al. Relationship between musculoskeletal ultrasound features and inflammatory factors in rheumatoid knee arthritis and its role in curative effect evaluation[J]. Journal of Xinjiang Medical University, 2025, 48(7): 957-962, 967.
    [19]
    许月霞, 郭月蓉, 蔡少桐, 等. 温经散寒方联合中药熏蒸治疗寒湿痹阻型类风湿关节炎的疗效及对炎症细胞因子的影响[J]. 延边大学医学学报, 2025, 48(9): 114-117.

    Xu Y X, Guo Y R, Cai S T, et al. Curative effect of Wenjing Sanhan Recipe combined with traditional Chinese medicine fumigation on rheumatoid arthritis of cold-dampness obstruction syndrome and its influence on inflammatory cytokines[J]. Journal of Medical Science Yanbian University, 2025, 48(9): 114-117.

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