Volume 24 Issue 6
Jun.  2026
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Article Navigation >  Chinese Journal of General Practice  > 2026  >  24(6): 944-947
LU Bangdong, LOU Yanting, ZHANG Yu, WANG Feifei, ZHOU Mengjiao, GU Rong. Efficacy analysis and safety evaluation of multi-endoscopy combination intrarenal surgery for complex renal calculi[J]. Chinese Journal of General Practice, 2026, 24(6): 944-947. doi: 10.16766/j.cnki.issn.1674-4152.004527
Citation: LU Bangdong, LOU Yanting, ZHANG Yu, WANG Feifei, ZHOU Mengjiao, GU Rong. Efficacy analysis and safety evaluation of multi-endoscopy combination intrarenal surgery for complex renal calculi[J]. Chinese Journal of General Practice, 2026, 24(6): 944-947. doi: 10.16766/j.cnki.issn.1674-4152.004527
shu

Efficacy analysis and safety evaluation of multi-endoscopy combination intrarenal surgery for complex renal calculi

doi: 10.16766/j.cnki.issn.1674-4152.004527

  • Department of Urology, the Fourth Affiliated Hospital of Anhui University of Medicine, Chaohu, Anhui 238000, China

Funds:

 KJ2021A0335

  • Received Date: 2025-04-23
    Available Online: 2026-11-10
    Abstract
  •   Objective  To investigate the stone-free rate, postoperative complications, and other indicators of percutaneous nephrolithotomy (PCNL) combined with flexible ureteroscopic holmium laser lithotripsy in the treatment of complex renal calculi, so as to evaluate its clinical application value.  Methods  The clinical data of 53 patients with complex renal calculi admitted to the Fourth Affiliated Hospital of Anhui University of Medicine from January 2022 to September 2024 were retrospectively analyzed. According to the treatment method, the patients were divided into a PCNL group (control group, n=27) and a multi-endoscopy combination group (observation group, n=26). The operation time, hospital stay, hospitalization costs, primary stone clearance rate, number of access tracts, renal function indicators, bleeding and infection indicators, pain scores, and complications were compared between the two groups.  Results  The average operation time, hospital stay, and hospitalization costs in the observation group were lower than those in the control group [(128.54±20.73) min vs. (160.81±28.24) min; (9.04±2.52) d vs. (11.04±2.88) d; (17 800±1 900) RMB vs. (20 200±3 100) RMB]. Additionally, the observation group had a higher primary stone clearance rate [84.62% (22/26) vs. 55.56% (15/27)] and fewer access tracts (1.27±0.45 vs. 2.37±0.69), with statistically significant differences (P < 0.05). There were no statistically significant differences in preoperative creatinine (Cr), blood urea nitrogen (BUN), and β2-microglobulin (β2-MG) between the two groups, but postoperative differences were statistically significant. The differences in Hb, hs-CRP, and PCT levels before and after surgery were lower in the observation group than that in the control group, with statistically significant differences (P < 0.05). At 6 hours postoperatively, the VAS score in the observation group was lower than that in the control group (P < 0.05), but no statistically significant differences were observed at 12 hours and 24 hours postoperatively. The total incidence of postoperative complications in the observation group was lower than that in the control group (P < 0.05).  Conclusion  Percutaneous nephrolithotomy combined with flexible ureteroscopic holmium laser lithotripsy for the treatment of complex renal calculi can improve the primary stone clearance rate, reduce postoperative complications, and is safe and effective.

     

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