Volume 24 Issue 4
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WANG Ning, GUO Ying, WANG Xuejing, ZHU Hongmin. Clinical study on prone position ventilation regulation of oxygenation and circulatory function in children with hypoxemia after congenital heart disease surgery[J]. Chinese Journal of General Practice, 2026, 24(4): 613-617. doi: 10.16766/j.cnki.issn.1674-4152.004452
Citation: WANG Ning, GUO Ying, WANG Xuejing, ZHU Hongmin. Clinical study on prone position ventilation regulation of oxygenation and circulatory function in children with hypoxemia after congenital heart disease surgery[J]. Chinese Journal of General Practice, 2026, 24(4): 613-617. doi: 10.16766/j.cnki.issn.1674-4152.004452
shu

Clinical study on prone position ventilation regulation of oxygenation and circulatory function in children with hypoxemia after congenital heart disease surgery

doi: 10.16766/j.cnki.issn.1674-4152.004452

  • Department of Cardiac Surgery, Beijing Children's Hospital Capital Medical University, National Children's Medical Center, Beijing 100045, China

Funds:

 7232366

  • Received Date: 2025-09-28
    Abstract
  •   Objective  This study explores the effects of prone positioning ventilation on oxygenation function, circulatory function regulation, and clinical safety in children with postoperative hypoxemia following congenital heart disease surgery, aiming to provide a basis for selecting respiratory intervention strategies in clinical practice.  Methods  A retrospective analysis was conducted on the clinical data of 160 children with postoperative hypoxemia due to congenital heart disease admitted to Beijing Children's Hospital Capital Medical University from November 2022 to November 2025. Eighty children who received alternating supine and lateral position ventilation interventions were included in the control group, and 80 children who received intermittent prone position ventilation interventions were included in the observation group. The oxygenation function, circulatory function indicators, and incidence of complications were compared between the two groups before ventilation and at 4, 8, and 12 hours of ventilation.  Results  The arterial partial pressure of carbon dioxide (PaCO2) levels in the observation group at 4, 8, and 12 h of ventilation were (50.35 ± 5.02) mmHg (1 mmHg=0.133 kPa), (46.15 ± 4.61) mmHg, and (41.38 ± 3.97) mmHg, respectively, all of which were lower than those in the control group[(53.55 ± 4.92) mmHg, (50.19 ± 4.25) mmHg, and (47.71 ± 4.31) mmHg]. Moreover, the differences in arterial partial pressure of oxygen (PaO2)/fraction of inspiration O2 (FiO2) and percutaneous arterial oxygen saturation (SpO2) levels between the two groups were statistically significant (P < 0.05).The total incidence of complications in the observation group was 6.25% (5/80), which was lower than 23.75% (19/80) in the control group, and the difference was statistically significant (P < 0.05).  Conclusion  Along with prolonged ventilation time, prone position ventilation can improve oxygenation function in children with hypoxemia after congenital heart disease surgery, maintain stable circulatory function, and have fewer complications, making it safe and effective.

     

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