Volume 22 Issue 10
Oct.  2024
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Article Navigation >  Chinese Journal of General Practice  > 2024  >  22(10): 1787-1790
LIU Qindong, LIU Yin, LI Yanyan, LI Zhi, YU Yingying. Application effect of prescription pre-audit system in medication management of PPIs[J]. Chinese Journal of General Practice, 2024, 22(10): 1787-1790. doi: 10.16766/j.cnki.issn.1674-4152.003734
Citation: LIU Qindong, LIU Yin, LI Yanyan, LI Zhi, YU Yingying. Application effect of prescription pre-audit system in medication management of PPIs[J]. Chinese Journal of General Practice, 2024, 22(10): 1787-1790. doi: 10.16766/j.cnki.issn.1674-4152.003734
shu

Application effect of prescription pre-audit system in medication management of PPIs

doi: 10.16766/j.cnki.issn.1674-4152.003734

  • Department of Pharmacy, the Second People' s Hospital of Kashgar, Xinjiang Uyghur Autonomous Region, Kashi, Xinjiang 844000, China

Funds:

 2021D01C029

 KS2020016

  • Received Date: 2023-11-30
    Available Online: 2024-12-28
    Abstract
  •   Objective   To explore the application effect of pre-prescription review system in the fine management of proton pump inhibitor (PPIs) medication, and to promote clinical rational drug use.   Methods   The rule-base system was established for the pre-prescription review process, and based on actual PPIs usage patterns in our hospital, we refined the indications, usage and dosage, combined medication rules, and course of treatment of PPIs. The use of PPIs before (January to April 2021) and after (May to August 2021) fine management was counted. A total of 23 medical staff working in prescription and review of PPIs were selected, and the satisfaction of medical staff before and after management was compared.   Results   The use of PPIs in our hospital decreased after fine management, from 515 600 yuan before management to 104 900 yuan (May), 143 100 yuan (June), 83 900 yuan (July), 97 800 yuan (August) after management. The total amount of PPIs medication showed a downward trend. After careful management, the incidence of unreasonable PPIs prescriptions in our hospital decreased. The unsuitable usage and dosage decreased from 14.2% before management to 5.1% (May), 3.6% (June), 2.0% (July), 1.3% (August). Indications inappropriate also decreased from 15.5% before management to 7.4%, 5.4%, 2.6%, 0.8% after management. Inappropriate combination medication decreased from 1.3% before management to 0.6%, 0, 0, 0 after management. Similarly, the inappropriate course of treatment decreased from 16.8% before management to 4.6%, 1.8%, 0, 0 after management. The overall satisfaction rate of medical staff increased following this new system [95.65% (22/23) vs. 69.57% (16/23), χ2=5.447, P < 0.05].   Conclusion   Pre-prescription review system used in PPIs fine management can effectively promote clinical rational drug use and improve the satisfaction of medical workers.

     

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