Volume 21 Issue 10
Oct.  2023
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SUN Yi, ZHENG Huifen. Analysis of sleep characteristics in elderly patients with insomnia and mild cognitive impairment[J]. Chinese Journal of General Practice, 2023, 21(10): 1640-1642. doi: 10.16766/j.cnki.issn.1674-4152.003188
Citation: SUN Yi, ZHENG Huifen. Analysis of sleep characteristics in elderly patients with insomnia and mild cognitive impairment[J]. Chinese Journal of General Practice, 2023, 21(10): 1640-1642. doi: 10.16766/j.cnki.issn.1674-4152.003188
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Analysis of sleep characteristics in elderly patients with insomnia and mild cognitive impairment

doi: 10.16766/j.cnki.issn.1674-4152.003188
  • 1.

    Clinical School, Jiangsu Health Vocational College, Nanjing, Jiangsu 210029, China

Funds:

 H2019052

  • Received Date: 2023-06-04
    Available Online: 2023-11-23
    Abstract
  •   Objective  To observe the sleep characteristics of elderly patients with insomnia combined with mild cognitive impairment (MCI) and the effect of behavioral cognitive impairment.  Methods  A total of 56 insomnia patients were selected from the Inpatient Department and Outpatient Department of the Department of Neurology of Jiangsu Geriatrics Hospital from January 2020 to December 2021, including 30 insomnia of normal cognition patients and 26 insomnia patients combined with MCI. The Pittsburgh Sleepiness Quotient Index (PSQI) scale, Self-Assessment Scale for Anxiety (SAS) scale and polysomnography (PSG) monitoring were compared between the two groups. The insomnia combined with MCI group were treated with short-range behavioral cognitive therapy for 4 weeks, and then to observe the therapeutic effect.  Results  The MoCA score of insomnia combined with MCI group was lower than that of insomnia of normal cognition group [(22.16±1.26) points vs. (26.20±0.53) points, t=16.019, P < 0.001], and the SAS score was higher than insomnia of normal cognition group [(38.22±3.31) points vs. (26.19±5.42) points, t=9.833, P < 0.001]. The scores of PSQI, sleep quality, fall asleep time, sleep time and sleep efficiency of insomnia combined with MCI group were higher than those of insomnia of normal cognition group, and the differences were statistically significant (all P < 0.05). The PSG results showed that the sleep latency was significantly prolonged in the insomnia combined with MCI group, the total sleep time was reduced compared with the insomnia of normal cognition group, and the percentage of NREM light sleep was higher, with statistical significance (all P < 0.05), but the number of awakenings and sleep efficiency were not significantly different compared with the insomnia of normal cognition group (all P>0.05). After intervention, MoCA score of some patients in the insomnia combined with MCI group improved, and SAS scores decreased, the difference was statistically significant. The total score of PSQI decreased compared with that before intervention, and the difference was not statistically significant, but three sub-items of sleep quality, falling asleep time and sleep efficiency were significantly improved compared with that before intervention, and the difference was statistically significant (all P < 0.05).  Conclusion  Patients with insomnia combined with MCI have significantly longer sleep latency, NREM shallow sleep time, poor subjective perception of sleep quality, and lower overall sleep efficiency. Cognitive behavioral intervention therapy has a good effect.

     

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