Characteristics of intestinal flora in children with ADHD and combined with obesity

ZHOU Guo-ling; ZHANG Xun; LIAO Wen-jing; LIU Yan; YU Rong-rong

doi:10.16766/j.cnki.issn.1674-4152.002237

Volume 19 Issue 12

Dec. 2021

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Article Navigation > Chinese Journal of General Practice > 2021 > 19(12): 2061-2064

ZHOU Guo-ling, ZHANG Xun, LIAO Wen-jing, LIU Yan, YU Rong-rong. Characteristics of intestinal flora in children with ADHD and combined with obesity[J]. Chinese Journal of General Practice, 2021, 19(12): 2061-2064. doi: 10.16766/j.cnki.issn.1674-4152.002237

Citation:

ZHOU Guo-ling, ZHANG Xun, LIAO Wen-jing, LIU Yan, YU Rong-rong. Characteristics of intestinal flora in children with ADHD and combined with obesity[J]. Chinese Journal of General Practice, 2021, 19(12): 2061-2064. doi: 10.16766/j.cnki.issn.1674-4152.002237

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Characteristics of intestinal flora in children with ADHD and combined with obesity

doi: 10.16766/j.cnki.issn.1674-4152.002237

1.
Department of Child Psychology, Hangzhou Seventh People's Hospital, Hangzhou, Zhejiang 310000, China

Funds:

2019KY517

Received Date: 2020-07-04
Available Online: 2022-03-02

Abstract

Abstract

Objective To discuss and explore the distribution characteristics of intestinal flora in children with attention deficit hyperactivity disorder (ADHD) complicated with obesity. Methods 64 children with attention deficit hyperactivity disorder (ADHD) admitted to Hangzhou Seventh people's Hospital from August 2018 to October 2019 were divided into 32 children with normal weight ADHD (control group) and 32 obese children with ADHD (experimental observation group). The macrogenomic sequencing method of faecal flora was used to compare the α diversity of microflora, relative abundance of species classification and differences in the number of bacteria between the two groups of children. Results No significant difference in the α diversity of intestinal microflora was observed between the experimental group and control group (all P>0.05). With regard to bacteria genus, the abundance of Veillonella and Enterococcus in the experimental observation group was lower than that in the control group, but the abundance of Flavobacteriaceae and Enterococcus in the experimental group was higher than that in the control group (all P < 0.05). With regard to bacteria species, the abundance of Lachnospira, Prausnitzii, Veillonella and active rumen cocci in the experimental group was lower than that in the control group, whereas the abundance of Pseudomonas aeruginosa, Bacteroides faecalis and Bacteroides viscera in the experimental group was higher than that in the control group (all P < 0.05). The number of rectal true bacteria in the control group was significantly higher than that in the experimental group, whereas the number of Bacteroides polymorpha, Bifidobacterium and Lactobacillus in the control group was significantly lower than that in the experimental group (all P < 0.05). Conclusion The changes of intestinal flora in children with ADHD and obesity may provide reference for the treatment of children with ADHD.
- Attention deficit hyperactivity disorder,
- Obesity,
- Intestinal flora,
- Children

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References

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Characteristics of intestinal flora in children with ADHD and combined with obesity

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