Volume 19 Issue 8
Aug.  2021
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Article Navigation >  Chinese Journal of General Practice  > 2021  >  19(8): 1262-1264, 1286
ZENG Rong, YAN Jiafu, ZHENG Keyang, WANG ZAuoguang, QU Fengxue, MU Yifan, CHENG Wenli. Relationship between fasting triglyceride glucose index and arteriosclerosis in patients with essential hypertension[J]. Chinese Journal of General Practice, 2021, 19(8): 1262-1264, 1286. doi: 10.16766/j.cnki.issn.1674-4152.002035
Citation: ZENG Rong, YAN Jiafu, ZHENG Keyang, WANG ZAuoguang, QU Fengxue, MU Yifan, CHENG Wenli. Relationship between fasting triglyceride glucose index and arteriosclerosis in patients with essential hypertension[J]. Chinese Journal of General Practice, 2021, 19(8): 1262-1264, 1286. doi: 10.16766/j.cnki.issn.1674-4152.002035
shu

Relationship between fasting triglyceride glucose index and arteriosclerosis in patients with essential hypertension

doi: 10.16766/j.cnki.issn.1674-4152.002035
  • 1.

    Department of Hypertension, Beijing Anzhen Hospital, Capital Medical University, Beijing 100029, China

Funds:

 81370229

  • Received Date: 2021-04-13
    Available Online: 2022-02-16
    Abstract
  •   Objective  To study the ambulatory blood pressure and brachial-ankle pulse wave velocity (ba-PWV) in essential hypertension patients with different fasting triglyceride glucose index (TyG index) groups, and to explore the correlation between TyG index and ba-PWV.  Methods  This retrospective study selected 466 inpatients with essential hypertension from August 2014 to December 2015. According to TyG index, the patients were divided into three groups by trisection. The differences of ambulatory blood pressure and ba-PWV among the three groups were compared, and the influencing factors of ba-PWV were analyzed by multiple linear regression model.  Results  With the increase of TyG index, the ratios of hyperlipidemia and diabetes of the patients raised, the average BMI increased, and the levels of total cholesterol, triglyceride, low density lipoprotein cholesterol, uric acid and fasting blood glucose evaluated gradually. The average systolic and diastolic blood pressure of 24 hours in the highest TyG index group were significantly higher than those in the lowest TyG index group [(132.3±14.8) mm Hg vs. (127.0±14.9) mm Hg, P=0.003; (81.1±11.8) mm Hg vs. (77.8±11.5) mm Hg, P=0.038], the average heart rate of 24 hours in the highest TyG index group was significantly higher than that in the lowest TyG index group (P=0.002). Ba-PWV was significantly higher in the highest TyG index group than that in the lowest TyG index group [(1 734.6±908.1) cm/s vs. (1 560.2±312.5) cm/s, P=0.022]. Multiple linear regression analysis showed that age, 24-hour systolic blood pressure and TyG index were the affecting factors of ba-PWV.  Conclusion  TyG index was positively correlated with blood pressure, heart rate and ba-PWV. It can be used to predict atherosclerosis in clinical practice.

     

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