Volume 15 Issue 7
Aug.  2022
Turn off MathJax
Article Contents
ZHANG Hui, JIANG Rong, ZHAO Sheng, ZHENG Liyun. Amino terminal B-type natriuretic peptide precursor relevance to modified Ross score and evaluation the value of left to right shunt congenital heart disease cardiac function[J]. Chinese Journal of General Practice, 2017, 15(7): 1109-1112. doi: 10.16766/j.cnki.issn.1674-4152.2017.07.005
Citation: ZHANG Hui, JIANG Rong, ZHAO Sheng, ZHENG Liyun. Amino terminal B-type natriuretic peptide precursor relevance to modified Ross score and evaluation the value of left to right shunt congenital heart disease cardiac function[J]. Chinese Journal of General Practice, 2017, 15(7): 1109-1112. doi: 10.16766/j.cnki.issn.1674-4152.2017.07.005

Amino terminal B-type natriuretic peptide precursor relevance to modified Ross score and evaluation the value of left to right shunt congenital heart disease cardiac function

doi: 10.16766/j.cnki.issn.1674-4152.2017.07.005
  • Received Date: 2016-08-22
    Available Online: 2022-08-04
  • Objective To study the left to right shunt congenital heart disease (congenital heart diseases, CHD) in children with heart failure when plasma amino-terminal B-type Natriuretic Peptide Precursor (Amino Terminal B-type Natriuretic Peptide, NT-pro BNP) changes and its value in the evaluation of cardiac function, analyze the correlation with modified Ross score, search for pediatric heart failure rapid detection methods. Methods The object of study is 55 cases left to right shunt CHD patients.According to the modified Ross score, the patients were divided into four groups, and the before and after treatment were compared.An alternate 12 cases in the same period in the hospital without CHD and heart failure in children as control group.With the United States (Roche) rapid heart failure diagnosis instrument determination of all children with plasma NT-pro BNP level, analyze its significance. Results The NT-pro BNP and modified Ross score into positive correlation (r=0.859), the children with CHD NT-pro BNP level obviously higher than that of control group, with statistical significance (P < 0.05), there were significant difference among heart failure group (P < 0.05).Children with heart failure after treatment, plasma NT-pro BNP levels significantly decreased, with statistical significance (P <0.001), the NT-pro BNP in the diagnosis of cardiac insufficiency of cutoff value was 286.5 pg/ml. Conclusion Different degree of heart failure in children with NT-pro BNP have a significant difference, the plasma NT-pro BNP can be used as the infant left to right shunt CHD with heart failure an objective indicator of cardiac function evaluation.

     

  • loading
  • 加载中

Catalog

    通讯作者: 陈斌, bchen63@163.com
    • 1. 

      沈阳化工大学材料科学与工程学院 沈阳 110142

    1. 本站搜索
    2. 百度学术搜索
    3. 万方数据库搜索
    4. CNKI搜索

    Article Metrics

    Article views (216) PDF downloads(0) Cited by()
    Proportional views
    Related

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return
    Return