Analysis of risk factors for early recurrence of pediatric intussusception after ultrasound-guided warm saline enema reduction

ZHOU Kai; LIU Xingyu; DUAN Jinjiang; LI Yang

doi:10.16766/j.cnki.issn.1674-4152.004123

Volume 23 Issue 8

Aug. 2025

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ZHOU Kai, LIU Xingyu, DUAN Jinjiang, LI Yang. Analysis of risk factors for early recurrence of pediatric intussusception after ultrasound-guided warm saline enema reduction[J]. Chinese Journal of General Practice, 2025, 23(8): 1316-1319. doi: 10.16766/j.cnki.issn.1674-4152.004123

Citation:

ZHOU Kai, LIU Xingyu, DUAN Jinjiang, LI Yang. Analysis of risk factors for early recurrence of pediatric intussusception after ultrasound-guided warm saline enema reduction[J]. Chinese Journal of General Practice, 2025, 23(8): 1316-1319. doi: 10.16766/j.cnki.issn.1674-4152.004123

Citation:

ZHOU Kai, LIU Xingyu, DUAN Jinjiang, LI Yang. Analysis of risk factors for early recurrence of pediatric intussusception after ultrasound-guided warm saline enema reduction[J]. Chinese Journal of General Practice, 2025, 23(8): 1316-1319. doi: 10.16766/j.cnki.issn.1674-4152.004123

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Analysis of risk factors for early recurrence of pediatric intussusception after ultrasound-guided warm saline enema reduction

doi: 10.16766/j.cnki.issn.1674-4152.004123

ZHOU Kai¹
, LIU Xingyu¹
, DUAN Jinjiang¹
, LI Yang^{2
,
,}

1.
Department of Pediatric Surgery, the First Affiliated Hospital of Bengbu Medical University, Bengbu, Anhui 233004, China

Funds:

AHWJ2023A20372

Received Date: 2025-01-22
Available Online: 2025-10-31

Abstract

Abstract

Objective To investigate the independent risk factors for early recurrence after ultrasound-guided warm saline enema reduction in children with intussusception, and to provide evidence for optimizing clinical treatment strategies. Methods A retrospective cohort study design was adopted, including 209 children with acute intussusception admitted to the First Affiliated Hospital of Bengbu Medical University from December 2018 to December 2024. All cases were diagnosed by ultrasound and treated with ultrasound-guided warm saline enema reduction. Clinical data such as the onset time of the disease, dehydration status, location and type of intussusception were recorded. Univariate and multivariate logistic regression model was used to analyze the independent risk factors for recurrence within 48 hours after reduction. Results Among the cases, 194 (92.82%) achieved successful reduction, while 15 (7.18%) experienced recurrence within 48 hours. Multivariate analysis revealed that duration of symptoms >24 hours (OR=3.168, 95% CI: 1.570-6.393, P=0.001), dehydration (OR=5.324, 95% CI: 1.090-26.012, P=0.039), initial intussusception head located at the splenic flexure and distal descending colon (OR=6.951, 95% CI: 1.519-31.813, P=0.012), and ileo-ileocolic type intussusception (OR=3.848, 95% CI: 1.003-14.760, P=0.049) were independent risk factors for early recurrence after reduction (all P < 0.05). Abdominal distension (OR=2.305, 95% CI: 0.591-8.993, P=0.229) and bloody stool (OR=2.331, 95% CI: 0.585-9.297, P=0.230) showed no significant association. Conclusion The key risk factors for early recurrence after ultrasound-guided warm saline enema reduction are onset time of illness >24 hours, dehydration, initial intussusception head located at the splenic flexure and beyond the descending colon, and ileo-ileal type of intussusception. Clinically, individualized interventions should be developed targeting these factors, including shortening the time window from diagnosis to treatment, correcting dehydration status, and optimizing the reduction technique, in order to reduce the risk of recurrence.
- Intussusception,
- Children,
- Ultrasound-guided,
- Warm saline enema,
- Recurrence

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References(22)

References

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Analysis of risk factors for early recurrence of pediatric intussusception after ultrasound-guided warm saline enema reduction

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