Volume 22 Issue 2
Feb.  2024
Turn off MathJax
Article Contents
Article Navigation >  Chinese Journal of General Practice  > 2024  >  22(2): 202-205
GUO Jinlong, MIN Xuhong, SONG Biao, LI Yuan, WANG Hua. Comparative study of CT features in patients with drug-resistant pulmonary tuberculosis with or without diabetes mellitus[J]. Chinese Journal of General Practice, 2024, 22(2): 202-205. doi: 10.16766/j.cnki.issn.1674-4152.003365
Citation: GUO Jinlong, MIN Xuhong, SONG Biao, LI Yuan, WANG Hua. Comparative study of CT features in patients with drug-resistant pulmonary tuberculosis with or without diabetes mellitus[J]. Chinese Journal of General Practice, 2024, 22(2): 202-205. doi: 10.16766/j.cnki.issn.1674-4152.003365
shu

Comparative study of CT features in patients with drug-resistant pulmonary tuberculosis with or without diabetes mellitus

doi: 10.16766/j.cnki.issn.1674-4152.003365
  • 1.

    Comparative study of CT features in patients with drug-resistant pulmonary tuberculosis with or without diabetes mellitus

Funds:

 Z155080000004

  • Received Date: 2023-08-02
    Available Online: 2024-03-27
    Abstract
  •   Objective  To explore the chest CT features of drug-resistant pulmonary tuberculosis complicated with diabetic patients, in order to improve the understanding of its imaging findings.  Methods  A retrospective study was performed between 55 cases of drug-resistant pulmonary tuberculosis with diabetes mellitus (referred to as "concurrent DM group") admitted to Anhui Chest Hospital from June 2022 to May 2023 and 80 cases of drug-resistant pulmonary tuberculosis without diabetes mellitus (referred to as "non-concurrent DM group") who met the inclusion criteria during the same period, and the chest CT features of the two groups were compared and analyzed.  Results  In the concurrent DM group, the detection rates of destroyed lung, lobar and segmental consolidation or caseous pneumonia and tuberculous pleurisy were 32.73% (18/55), 36.36% (20/55) and 41.82% (23/55), respectively, and the non-concurrent DM group were 13.75% (11/80), 20.00% (16/80) and 23.75% (19/80), respectively. The differences between the two groups were statistically significant (χ2=6.959, 4.463, 4.965, P<0.05). In the concurrent DM group, the detection rates of case of cavities and cavities without wall were 89.09%(49/55), 54.82%(108/197), respectively, and the non-concurrent DM group were 67.50% (54/80), 44.09% (82/186), respectively. The differences between the two groups were statistically significant (χ2=8.401, 4.411, P<0.05).  Conclusion  The chest CT features of drug-resistant pulmonary tuberculosis with diabetes mellitus has certain characteristics, which are more manifested as destroyed lung, lobar and segmental consolidation or caseous pneumonia, and multiple cavities without wall. Effective understanding of the imaging characteristics can provide help for early clinical diagnosis and treatment.

     

    • FullText(HTML)
  • loading
    • References(20)
  • [1]
    邓国防, 成诗明. 浅谈我国结核病与糖尿病共病治疗管理现状[J]. 中国防痨杂志, 2021, 43(1): 23-25. doi: 10.3969/j.issn.1000-6621.2021.01.005

    DENG G F, CHENG S M. The challenge of clinical management and treatment of tuberculosis and diabietes in China[J]. Chinese Journal of Antituberculosis, 2021, 43(1): 23-25. doi: 10.3969/j.issn.1000-6621.2021.01.005
    [2]
    胡卫华, 金龙, 初乃惠. 耐多药/广泛耐药肺结核并发2型糖尿病患者耐药特征分析[J]. 中国防痨杂志, 2021, 43(1): 26-30. https://www.cnki.com.cn/Article/CJFDTOTAL-ZFLZ202101007.htm

    HU W H, JIN L, CHU N H. Analysis of drug resistance characteristics of MDR/XDR-TB patients complicated with type 2 diabetes mellitus[J]. Chinese Journal of Antituberculosis, 2021, 43(1): 26-30. https://www.cnki.com.cn/Article/CJFDTOTAL-ZFLZ202101007.htm
    [3]
    WU Q, WANG M, ZHANG Y, et al. Epidemiological characteristics and their influencing factors among pulmonary tuberculosis patients with and without diabetes mellitus: a survey study from drug resistance surveillance in east China[J]. Front Public Health, 2022, 9: 777000. DOI: 10.3389/fpubh.2021.777000.
    [4]
    PAN Y P, YU Y Y, YI Y H, et al. The differences in drug resistance between drug-resistant tuberculosis patients with and without diabetes mellitus in northeast China: a retrospective study[J]. BMC Infect Dis, 2023, 23(1): 162. doi: 10.1186/s12879-023-08130-1
    [5]
    杨子龙, 袁园, 汪敏, 等. 糖尿病与肺结核共病结核分枝杆菌耐药情况分析[J]. 实用医学杂志, 2023, 39(11): 1359-1363. https://www.cnki.com.cn/Article/CJFDTOTAL-SYYZ202311007.htm

    YANG Z L, YUAN Y, WANG M, et al. Drug resistance of Mycobacterium tuberculosis co-occurring with diabetes and tuberculosis[J]. The Journal of Practical Medicine, 2023, 39(11): 1359-1363. https://www.cnki.com.cn/Article/CJFDTOTAL-SYYZ202311007.htm
    [6]
    张幽蕾, 周笑, 吴灵君, 等. 肺结核患者结核分枝杆菌利福平基因突变特征及耐药情况[J]. 中华全科医学, 2020, 18(12): 2029-2031, 2139. doi: 10.16766/j.cnki.issn.1674-4152.001680

    ZHANG Y L, ZHOU X, WU L J, et al. Mutation characteristics and drug resistance of rifampicin gene of Mycobacterium tuberculosis in patients with pulmonary tuberculosis[J]. Chinese Journal of General Practice, 2020, 18(12): 2029-2031, 2139. doi: 10.16766/j.cnki.issn.1674-4152.001680
    [7]
    中国防痨协会. 耐药结核病化学治疗指南(2019年简版)[J]. 中国防痨杂志, 2019, 41(10): 1025-1073. https://www.cnki.com.cn/Article/CJFDTOTAL-ZFLZ202103018.htm

    Chinese Antituberculosis Association. Guidelines on chemotherapy of drug-resistant tuberculosis (2019 abbreviated version)[J]. Chinese Journal of Antituberculosis, 2019, 41(10): 1025-1073. https://www.cnki.com.cn/Article/CJFDTOTAL-ZFLZ202103018.htm
    [8]
    中华医学会糖尿病学分会. 中国2型糖尿病防治指南(2020年版)[J]. 中华糖尿病杂志, 2021, 13(4): 315-409. https://www.cnki.com.cn/Article/CJFDTOTAL-HBYX202112018.htm

    Diabetes Society of Chinese Medical Association. Guideline for the prevention and treatment of type 2 diabetes mellitus in China (2020 edition)[J]. Chinese Journal of Diabetes, 2021, 13(4): 315-409. https://www.cnki.com.cn/Article/CJFDTOTAL-HBYX202112018.htm
    [9]
    张雅婷, 郝晓刚, 王炜, 等. 衢州市肺结核合并糖尿病病例特征分析[J]. 预防医学, 2023, 35(1): 57-60. https://www.cnki.com.cn/Article/CJFDTOTAL-ZYFX202301013.htm

    ZHANG Y T, HAO X G, WANG W, et al. Characteristics of pulmonary tuberculosis patients complicated by diabetes mellitus in Quzhou City[J]. Preventive Medicine, 2023, 35(1): 57-60. https://www.cnki.com.cn/Article/CJFDTOTAL-ZYFX202301013.htm
    [10]
    李雪, 李楠楠, 任斐, 等. 耐多药肺结核合并糖尿病的临床特点及治疗结局[J]. 中国热带医学, 2021, 21(10): 990-995. https://www.cnki.com.cn/Article/CJFDTOTAL-RDYX202110016.htm

    LI X, LI N N, REN F, et al. Clinical characteristics and treatment outcome of multidrug-resistant pulmonary tuberculosis complicated with diabetes mellitus[J]. China Tropical Medicine, 2021, 21(10): 990-995. https://www.cnki.com.cn/Article/CJFDTOTAL-RDYX202110016.htm
    [11]
    李硕兰, 李明武, 李光妹, 等. 中国耐多药肺结核不良治疗转归影响因素的Meta分析[J]. 中国防痨杂志, 2022, 44(12): 1303-1313. https://www.cnki.com.cn/Article/CJFDTOTAL-ZFLZ202212010.htm

    LI S L, LI M W, LI G M, et al. Influencing factors of getting unfavorable treatment outcomes of patients with multidrug-resistant pulmonary tuberculosis in China: a Meta-analysis[J]. Chinese Journal of Antituberculosis, 2022, 44(12): 1303-1313. https://www.cnki.com.cn/Article/CJFDTOTAL-ZFLZ202212010.htm
    [12]
    何萍, 姚华彦, 崔斌, 等. 2013—2020年上海2型糖尿病临床大数据人群结构分析报告[J]. 中国医药科学, 2022, 12(16): 5-7, 12. https://www.cnki.com.cn/Article/CJFDTOTAL-GYKX202216002.htm

    HE P, YAO H Y, CUI B, et al. Population structure analysis of clinical big data of type 2 diabetes mellitus in Shanghai from 2013 to 2020[J]. China Medicine And Pharmacy, 2022, 12(16): 5-7, 12. https://www.cnki.com.cn/Article/CJFDTOTAL-GYKX202216002.htm
    [13]
    陈建飞, 郭丽丽. 肺结核合并糖尿病继发肺部真菌感染的临床特征与耐药性分析[J]. 北京医学, 2021, 43(9): 927-929. https://www.cnki.com.cn/Article/CJFDTOTAL-BJYX202109022.htm

    CHEN J F, GUO L L. Clinical characteristics and drug resistance analysis of pulmonary mycosis secondary to pulmonary tuberculosis and diabetes mellitus[J]. Beijing Medical Journal, 2021, 43(9): 927-929. https://www.cnki.com.cn/Article/CJFDTOTAL-BJYX202109022.htm
    [14]
    李朝俊, 孙诚鸿, 金文宇. 非结核分枝杆菌肺病与耐多药肺结核的胸部CT征象对照分析[J]. 临床荟萃, 2021, 36(6): 530-534. https://www.cnki.com.cn/Article/CJFDTOTAL-LCFC202106010.htm

    LI Z J, SUN C H, JIN W Y. Comparation of CT imaging characteristics between non-tuberculous mycobacterium tuberculosis and multi-drug resistant tuberculosis[J]. Clinical Focus, 2021, 36(6): 530-534. https://www.cnki.com.cn/Article/CJFDTOTAL-LCFC202106010.htm
    [15]
    梁瑞云, 方伟军, 任会丽, 等. 耐药肺结核伴空洞患者的CT表现特征分析[J]. 中国防痨杂志, 2021, 43(4): 341-345. https://www.cnki.com.cn/Article/CJFDTOTAL-ZFLZ202104008.htm

    LIANG R Y, FANG W J, REN H L, et al. Analysis of CT features of drug-resistant pulmonary tuberculosis with cavity[J]. Chinese Journal of Antituberculosis, 2021, 43(4): 341-345. https://www.cnki.com.cn/Article/CJFDTOTAL-ZFLZ202104008.htm
    [16]
    汪敏, 袁园, 谭守勇, 等. 2型糖尿病合并初治菌阳肺结核患者肺部广泛病灶和空洞发生的危险因素分析[J]. 中国防痨杂志, 2023, 45(8): 761-767. https://www.cnki.com.cn/Article/CJFDTOTAL-ZFLZ202308013.htm

    WANG M, YUAN Y, TAN S Y, et al. Analysis of risk factors for extensive lung focus and cavities in type 2 diabetes mellitus patients complicated with newly treated pulmonary tuberculosis[J]. Chinese Journal of Antituberculosis, 2023, 45(8): 761-767. https://www.cnki.com.cn/Article/CJFDTOTAL-ZFLZ202308013.htm
    [17]
    舒伟强, 李春华, 王惠秋, 等. 2型糖尿病并发肺结核患者血糖水平与CT特征的相关性分析[J]. 中国防痨杂志, 2017, 39(6): 565-569.

    SHU W Q, LI C H, WANG H Q, et al. The study on the relationship between blood glucose level's and chest CT features in diabetic patients complicated with pulmonary tuberculosis[J]. Chinese Journal of Antituberculosis, 2017, 39(6): 565-569.
    [18]
    SONG Q S, ZHANG G Q, JIANG H B, et al. Imaging features of pulmonary CT in type 2 diabetic patients with multidrug-resistant tuberculosis[J]. PLoS One, 2016, 11(3): e0152507. DOI: 10.1371/journal.pone.0152507.
    [19]
    黄倩, 刘德亮, 李惠林. 白细胞分化抗原36与2型糖尿病相关性的研究进展[J]. 中华全科医学, 2023, 21(7): 1206-1210. doi: 10.16766/j.cnki.issn.1674-4152.003085

    HUANG Q, LIU D L, LI H L. Research progress on correlations between CD36 and type 2 diabetes mellitus[J]. Chinese Journal of General Practice, 2023, 21(7): 1206-1210. doi: 10.16766/j.cnki.issn.1674-4152.003085
    [20]
    陈秋景, 覃勇民, 罗文昭. 2型糖尿病合并活动性肺结核患者糖化血红蛋白与结核分枝杆菌及利福平耐药检测的相关性分析[J]. 临床内科杂志, 2022, 39(11): 767-768. https://www.cnki.com.cn/Article/CJFDTOTAL-LCLZ202211014.htm

    CHEN Q J, QIN Y M, LUO W Z. Analysis of correlation between glycosylated hemoglobin and resistance to mycobacterium tuberculosis and rifampicin in type 2 diabetes patients with active pulmonary tuberculosis[J]. Journal of Clinical Internal Medicine, 2022, 39(11): 767-768. https://www.cnki.com.cn/Article/CJFDTOTAL-LCLZ202211014.htm
    • Relative Articles
    • Supplements(0)
    • Cited By
  • 加载中

Catalog

    通讯作者: 陈斌, bchen63@163.com
    • 1. 

      沈阳化工大学材料科学与工程学院 沈阳 110142

    1. 本站搜索
    2. 百度学术搜索
    3. 万方数据库搜索
    4. CNKI搜索

    Figures(3)  / Tables(3)

    Get Citation
    PDF
    XML

    Article Metrics

    Article views (86) PDF downloads(8) Cited by()
    Proportional views
    Related

    Address：No. 287, Changhuai Road, Bengbu, Anhui Province, 233004, P.R.ChinaphoneNo：0552-3066635； 0552-3051890Email：zhqkyx@163.com

    Copyright © Chinese Journal of General Practice皖ICP备2020018345号-2

    Supported by: Beijing Renhe Information Technology Co., Ltd.    

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return
    Return