Volume 21 Issue 11
Nov.  2023
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Article Navigation >  Chinese Journal of General Practice  > 2023  >  21(11): 1830-1833
ZHU Li, TANG Hailong, HU Lei, ZHAO Yinli, GUO Sijin. Application of quantitative goal exercise combined with whole process refined nutrition management in patients with hematological disease chemotherapy[J]. Chinese Journal of General Practice, 2023, 21(11): 1830-1833. doi: 10.16766/j.cnki.issn.1674-4152.003235
Citation: ZHU Li, TANG Hailong, HU Lei, ZHAO Yinli, GUO Sijin. Application of quantitative goal exercise combined with whole process refined nutrition management in patients with hematological disease chemotherapy[J]. Chinese Journal of General Practice, 2023, 21(11): 1830-1833. doi: 10.16766/j.cnki.issn.1674-4152.003235
shu

Application of quantitative goal exercise combined with whole process refined nutrition management in patients with hematological disease chemotherapy

doi: 10.16766/j.cnki.issn.1674-4152.003235
  • 1.

    Department of Hematology and Oncology, First Affiliated Hospital of Air Force Military Medical University, Xi' an, Shaanxi 710032, China

Funds:

 82100218

  • Received Date: 2022-11-17
    Available Online: 2024-01-13
    Abstract
  •   Objective  To explore the effect of quantitative targeted exercise (QGE) combined with whole process refined nutrition management (WP-RNM) on the clinical results of patients with hematologic diseases undergoing chemotherapy, and to provide evidence for improving the quality of rehabilitation management of patients with hematologic diseases after chemotherapy.  Methods  A total of 126 patients with hematologic diseases treated with chemotherapy in First Affiliated Hospital of Air Force Military Medical University from February 2019 to June 2021 were selected and randomly divided into observation group and control group with 63 patients in each group by random number table sampling method. The control group was treated with routine intervention, and the observation group was treated with QGE combined WP-RNM intervention program on the basis of routine intervention. The nutritional status, immune function and life quality of the two groups were compared before and after intervention.  Result  After intervention, the scores of hemoglobin (Hb), plasma prealbumin (PAB), albumin (Alb), transferrin (TRF) and scored patient-generated subjective global assessment(PG-SGA) in the observation group were significantly higher than those in the control group (all P<0.001). The PG-SGA score was significantly lower than that of the control group [(1.92±0.72) points vs. (4.26±0.81) points, t=17.138, P<0.01]. After intervention, the scores of quality of life questionnaire-C30 (QLQ-C30) in the observation group were significantly lower than those in the control group (all P<0.001). After intervention, serum IgG antibody (IgG), IgA antibody (IgA), IgM antibody (IgM), percentage of CD3+T cells and CD4+T cells in the observation group were significantly higher than those in the control group (t-values: 28.857, 6.683, 9.191, 20.013 and 12.798, respectively, all P<0.01).  Conclusion  QGE combined with WP-RNM can effectively improve the nutritional intake and immune function of patients with hematological diseases and improve the quality of life of patients.

     

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