Volume 21 Issue 10
Oct.  2023
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Article Navigation >  Chinese Journal of General Practice  > 2023  >  21(10): 1654-1656
FAN Tingting, LI Rui, ZHU Yuyou, SUN Wen, HU Wei, WANG Guoping. Risk factors for ventilator-associated pneumonia after mechanical thrombectomy in acute ischemic stroke[J]. Chinese Journal of General Practice, 2023, 21(10): 1654-1656. doi: 10.16766/j.cnki.issn.1674-4152.003192
Citation: FAN Tingting, LI Rui, ZHU Yuyou, SUN Wen, HU Wei, WANG Guoping. Risk factors for ventilator-associated pneumonia after mechanical thrombectomy in acute ischemic stroke[J]. Chinese Journal of General Practice, 2023, 21(10): 1654-1656. doi: 10.16766/j.cnki.issn.1674-4152.003192
shu

Risk factors for ventilator-associated pneumonia after mechanical thrombectomy in acute ischemic stroke

doi: 10.16766/j.cnki.issn.1674-4152.003192

  • Department of Neurology, the First Affiliated Hospital of University of Science and Technology of China, Hefei, Anhui 230001, China

Funds:

 82001452

  • Received Date: 2023-02-07
    Available Online: 2023-11-23
    Abstract
  •   Objective  To investigate the risk factors of ventilator-associated pneumonia (VAP) after mechanical thrombectomy in acute stroke and the predictive value of A2DS2 score scale.  Methods  From January 2020 to December 2021, the clinical data of 273 patients admitted to the Department of Neurology, the First Affiliated Hospital, University of Science and Technology of China (USTC) for acute cerebral infarction were retrospectively collected. The patients were divided into VAP group (180 cases) and non-VAP group (93 cases). A2DS2 scores were obtained for all patients. Multivariate logistic regression analysis was used to investigate the relationship between various factors and pneumonia. Receiver operating characteristic curve (ROC) was used to evaluate the predictive value of the A2DS2 scale for VAP.  Results  Age, length of hospital stay, history of hypertension, random blood glucose, NIHSS score, neutrophil to lymphocyte ratio (NLR), A2DS2 score were correlated with VAP (all P < 0.05). length of hospital stay and history of hypertension were independent risk factors for VAP (OR=1.112, 95% CI: 1.053-1.173, P < 0.001; OR=1.970, 95% CI: 1.130-3.433, P=0.017); A2DS2≥5 points was an independent risk factor for VAP (OR=2.412, 95% CI: 1.382-4.210, P=0.002). The A2DS2 score scale had predictive value for VAP (AUC=0.651, 95% CI: 0.580-0.721, sensitivity was 0.733, specificity was 0.484, and optimal cut-off value was 5 points).  Conclusion  Age, hospitalization days, history of hypertension, random blood glucose, NIHSS score, NLR, A2DS2 score were correlated with VAP. Long hospital stay, history of hypertension and high A2DS2 score were independent risk factors for VAP. The A2DS2 score scale has predictive value for stroke combined with VAP.

     

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