Predictive values of trends in peripheral blood inflammatory indexes for infectious abdominal complications after laparoscopic radical rectal cancer surgery

QIU Quanwei; GE Sitang; ZUO Lugen; LIU Mulin

doi:10.16766/j.cnki.issn.1674-4152.002976

Volume 21 Issue 5

May 2023

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Article Navigation > Chinese Journal of General Practice > 2023 > 21(5): 757-760

QIU Quanwei, GE Sitang, ZUO Lugen, LIU Mulin. Predictive values of trends in peripheral blood inflammatory indexes for infectious abdominal complications after laparoscopic radical rectal cancer surgery[J]. Chinese Journal of General Practice, 2023, 21(5): 757-760. doi: 10.16766/j.cnki.issn.1674-4152.002976

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QIU Quanwei, GE Sitang, ZUO Lugen, LIU Mulin. Predictive values of trends in peripheral blood inflammatory indexes for infectious abdominal complications after laparoscopic radical rectal cancer surgery[J]. Chinese Journal of General Practice, 2023, 21(5): 757-760. doi: 10.16766/j.cnki.issn.1674-4152.002976

Citation:

QIU Quanwei, GE Sitang, ZUO Lugen, LIU Mulin. Predictive values of trends in peripheral blood inflammatory indexes for infectious abdominal complications after laparoscopic radical rectal cancer surgery[J]. Chinese Journal of General Practice, 2023, 21(5): 757-760. doi: 10.16766/j.cnki.issn.1674-4152.002976

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Predictive values of trends in peripheral blood inflammatory indexes for infectious abdominal complications after laparoscopic radical rectal cancer surgery

doi: 10.16766/j.cnki.issn.1674-4152.002976

QIU Quanwei^{1, 2}
, GE Sitang^{1, 2}
, ZUO Lugen^{1, 2}
, LIU Mulin^{1, 2
,
,}

1.
Department of Gastrointestinal Surgery, the First Affiliated Hospital of Bengbu Medical College, Bengbu, Anhui 233004, China

Funds:

2108085MH291

KJ2021ZD0092

BYKC201909

Received Date: 2022-09-21

Abstract

Abstract

Objective To analyze the changes in peripheral blood inflammatory indicators and explore the predictive diagnostic values in predicting the occurrence of Intra-Abdominal Septic Complications (IASCs)in patients after laparoscopic rectal cancer surgery. Methods Patients who underwent laparoscopic radical surgery for rectal cancer in the First Affiliated Hospital of Bengbu Medical College from June 2020 to April 2022 were included as subjects in the study and were divided into IASC group and non-IASC group according to whether IASCs occurred. One hundred and fifty-six patients were included in this study, of which 19 cases (12.18%) were happened. The trend and predictive value of postoperative peripheral TNF-α, CRP and WBC for postoperative IASCs were analyzed in both groups. Results There was no significant difference between two groups in the levels of WBC, CRP and TNF-α in peripheral blood 1-day after surgery (P>0.05). The levels of TNF-α and CRP in peripheral blood 3-day after surgery were higher in IASC group than those in non-IASC group. ROC curve shows that the levels of TNF-α and CRP in peripheral blood 3 days after surgery predicted the occurrence of postoperative IASCs with negative predictive values above 80%, however, the positive predictive values were below 50%. Take ΔTNF-α and ΔCRP into ROC analysis. The results showed that the positive and negative predictive values of ΔTNF-α were superior to those of ΔCRP. Conclusion The changing trend of TNF-α in peripheral blood showed certain predictive and diagnostic values for IASCs after laparoscopic radical rectal cancer surgery.
- Laparoscopic radical resection of colorectal cancer,
- Intra-abdominal septic complications,
- Tumor necrosis factor α,
- C-reactive protein,
- Prognosis

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References

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Predictive values of trends in peripheral blood inflammatory indexes for infectious abdominal complications after laparoscopic radical rectal cancer surgery

doi: 10.16766/j.cnki.issn.1674-4152.002976