Volume 21 Issue 2
Feb.  2023
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HUANG Xiao-chen, ZHANG Yong, QIAN Zhao-xia. Clinical observation of Zheng's clinostatic rehabilitation exercise combined with respiratory expectoration valve on patients with severe chronic obstructive pulmonary disease[J]. Chinese Journal of General Practice, 2023, 21(2): 259-262. doi: 10.16766/j.cnki.issn.1674-4152.002859
Citation: HUANG Xiao-chen, ZHANG Yong, QIAN Zhao-xia. Clinical observation of Zheng's clinostatic rehabilitation exercise combined with respiratory expectoration valve on patients with severe chronic obstructive pulmonary disease[J]. Chinese Journal of General Practice, 2023, 21(2): 259-262. doi: 10.16766/j.cnki.issn.1674-4152.002859

Clinical observation of Zheng's clinostatic rehabilitation exercise combined with respiratory expectoration valve on patients with severe chronic obstructive pulmonary disease

doi: 10.16766/j.cnki.issn.1674-4152.002859
Funds:

 1804h08020287

 20200314

 2020byzd378

  • Received Date: 2022-01-27
    Available Online: 2023-04-20
  •   Objective  To investigate the clinical effect of Zheng's clinostatic rehabilitation exercise combined with breathing and expelling valve training in patients with severe chronic obstructive pulmonary disease.  Methods  A total of 62 patients with acute exacerbation of severe chronic obstructive pulmonary disease (AECOPD) admitted to the Respiratory Department of Bengbu Third People's Hospital from October 2020 to February 2021 were divided into observation group (n=31) and control group (n=31) by random number table method. All patients were given basic treatment such as anti-infection, antispasmolysis and expectoration and oxygen therapy. The control group received lip-shrinking abdominal rehabilitation treatment, and the observation group received Zheng's clinostatic rehabilitation exercise combined with respiratory expectoration valve. The study period was 12 weeks. Forced expiratory volume in one second (FEV1), forced vital capacity (FVC), FEV1/FVC, CRP, IL-6, CD3+, CD4+, CD45+, COPD assessment test (CAT) and modified British medical research council (mMRC) were observed in the two groups before and after intervention.  Results  After intervention, the levels of IL-6 [6.11(0.82, 10.83) pg/mL] and CRP [9.15(2.15, 18.91) mg/L] in the observation group were significantly lower than those in the control group [8.64(5.41, 15.54) pg/mL, 18.64(6.49, 26.15) mg/L, all P < 0.05]. The levels of CD3+, CD4+ and CD45+ in the observation group were significantly higher than those in control group (all P < 0.05). CAT [(28.03±4.53) points] and mMRC (3.10±0.70) in the observation group was improved compared with that in the control group [(28.77±4.31) points, 3.45±0.62, all P < 0.05]. No significant differences in FEV1, FVC and FEV1/FVC were found in the two groups before and after intervention (all P>0.05).  Conclusion  Zheng's clinostatic rehabilitation exercise combined with respiratory expectoration valve can effectively reduce inflammatory response, enhance immune function, improve dyspnoea and maintain stable lung function.

     

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  • [1]
    World Health Organization. Chronic obstructive pulmonary disease (COPD)[EB/OL]. (2022-05-20)[2022-05-28]. https://www.who.int/news-room/fact-sheets/detail/chronic-obstructive-pulmonary-disease-(COPD).
    [2]
    Global Initiative For Chronic Obstructive Lung Disease. Global strategy for the diagnosis, management and prevention of chronic obstructive pulmonary disease 2022 report[EB/OL]. (2021-11-15)[2021-12-15]. https://goldcopd.org/gold-reports/.
    [3]
    RYRS C K, GODTFREDSEN N S, KOFOD L M, et al. Lower mortality after early supervised pulmonary rehabilitation following COPD-exacerbations: a systematic review and meta-analysis[J]. BMC Pulm Med, 2018, 18(1): 154. doi: 10.1186/s12890-018-0718-1
    [4]
    沈科, 陈华芳. 郑氏卧位康复操对重度慢性阻塞性肺疾病稳定期患者的疗效探讨[J]. 中国社区医师, 2019, 35(28): 180-181. doi: 10.3969/j.issn.1007-614x.2019.28.122

    SHEN K, CHEN H F. Effect of Zheng's lying position rehabilitation exercise on patients with severe chronic obstructive pulmonary disease in stable stage[J]. Chinese Community Doctors, 2019, 35(28): 180-181. doi: 10.3969/j.issn.1007-614x.2019.28.122
    [5]
    HALPIN D, CELLI B R, CRINER G J, et al. The GOLD Summit on chronic obstructive pulmonary disease in low and middle income countries[J]. Int J Tuberc Lung Dis, 2019, 23(11): 1131-1141. doi: 10.5588/ijtld.19.0397
    [6]
    HANSEN H, BIELER T, BEYER N, et al. Supervised pulmonary telerehabilitation versus pulmonary rehabilitation in severe COPD: a randomised multicentre trial[J]. Thorax, 2020, 75(5): 413-421. doi: 10.1136/thoraxjnl-2019-214246
    [7]
    王辰, 迟春花, 陈荣昌, 等. 慢性阻塞性肺疾病基层诊疗指南(2018年)[J]. 中华全科医师杂志, 2018, 17(11): 856-870. doi: 10.3760/cma.j.issn.1671-7368.2018.11.002

    WANG C, CHI C H, CHEN R C, et al. Guideline for primary care of chronic obstructive pulmonary disease (2018)[J]. Chinese JOurnal of General Practitioners, 2018, 17(11): 856-870. doi: 10.3760/cma.j.issn.1671-7368.2018.11.002
    [8]
    王园, 刘妮, 杨峰, 等. 多功能呼气阀的原理及临床应用[J]. 国际呼吸杂志, 2018, 38(19): 1491-1494. doi: 10.3760/cma.j.issn.1673-436X.2018.19.010

    WANG Y, LIU N, YANG F, et al. Principle and clinical application of multifunctional exhalation valve[J]. International Journal of Respiration, 2018, 38(19): 1491-1494. doi: 10.3760/cma.j.issn.1673-436X.2018.19.010
    [9]
    李洁, 刘蕊, 陈葆青. 深呼吸训练器大负荷吸气肌训练对稳定期COPD患者肺功能和运动耐力的影响[J]. 中国医学装备, 2019, 16(4): 95-98. doi: 10.3969/J.ISSN.1672-8270.2019.04.026

    LI J, LIU R, CHEN B Q. Effects of inspiratory muscle training with heavy load of deep breath trainer on lung function and exercise endurance of patients with COPD at stable phase[J]. China Medical Equipment, 2019, 16(4): 95-98. doi: 10.3969/J.ISSN.1672-8270.2019.04.026
    [10]
    张平, 杨峰, 李寅环, 等. 呼吸训练器与缩唇呼气对AECOPD患者排痰效果的对比研究[J]. 国际呼吸杂志, 2020, 40(5): 349-350, 354. doi: 10.3760/cma.j.issn.1673-436X.2020.05.005

    ZHANG P, YANG F, LI Y H, et al. A comparative study of the expectoration effect by breath training device and pursed lip breathing in patients with AECOPD[J]. International Journal of Respiration, 2020, 40(5): 349-350, 354. doi: 10.3760/cma.j.issn.1673-436X.2020.05.005
    [11]
    严娴婷, 黄勍栋, 唐婷玉, 等. 血清炎症因子和肺功能与OSAHS患者病情程度的相关性研究[J]. 中华全科医学, 2021, 19(6): 947-949. doi: 10.16766/j.cnki.issn.1674-4152.001957

    YAN X T, HUANG Q D, TANG T Y, et al. Correlation of serum inflammatory factors and pulmonary function with the severity of OSAHS[J]. Chinese Journal of General Practice, 2021, 19(6): 947-949. doi: 10.16766/j.cnki.issn.1674-4152.001957
    [12]
    尹正录, 孟兆祥, 王继兵, 等. 肺康复对慢性阻塞性肺疾病稳定期患者BODE指数和血清炎症因子的影响[J/CD]. 中华临床医师杂志(电子版), 2019, 13(7): 521-526.

    YIN Z L, MENG Z X, WANG J B, et al. Effect of pulmonary rehabilitation on BODE index and serum inflammatory factors in patients with stable chronic obstructive pulmonary disease[J/CD]. Chinese Journal of Clinicians (Electronic Edition), 2019, 13(7): 521-526.
    [13]
    VIEIRA FABIOLA C O S, PEREIRA D S, COSTA T B, et al. Effects of a long term pulmonary rehabilitation program on functional capacity and inflammatory profile of older patients with COPD[J]. J Cardiopulm Rehabil Prev, 2018, 38(5): E12-E15. doi: 10.1097/HCR.0000000000000303
    [14]
    SZUCS B, SZUCS C, PETREKANITS M, et al. Molecular characteristics and treatment of endothelial dysfunction in patients with COPD: a review article[J]. Int J Mol Sci, 2019, 20(18): 4329. doi: 10.3390/ijms20184329
    [15]
    方英, 方群, 王世强, 等. 简化"六字诀"联合体外膈肌起搏对COPD稳定期患者肺康复的疗效评价[J]. 中华全科医学, 2021, 19(10): 1680-1684. doi: 10.16766/j.cnki.issn.1674-4152.002141

    FANG Y, FANG Q, WANG S Q, et al. Efficacy evaluation of simplified Six-word formula combined with extracorporeal phrenic pace-making in pulmonary rehabilitation of patients with COPD stable period[J]. Chinese Journal of General Practice, 2021, 19(10): 1680-1684. doi: 10.16766/j.cnki.issn.1674-4152.002141
    [16]
    赵丽丽, 王青霞. 止咳平喘十二味合剂联合乌苯美司胶囊对急性加重期慢性阻塞性肺疾病病人氧合指数、免疫失衡及炎性因子的影响[J]. 安徽医药, 2021, 25(12): 2519-2522. doi: 10.3969/j.issn.1009-6469.2021.12.043

    ZHAO L L, WANG Q X. Effects of Zhike Pingchuan twelve mixture combined with ubenimex capsule on oxygenation index, immune imbalance and inflammatory factors in patients with COPD[J]. Anhui Medical and Pharmaceutical Journal, 2021, 25(12): 2519-2522. doi: 10.3969/j.issn.1009-6469.2021.12.043
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