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LIAO Zhi-jun, YANG Zhi-yong, HUANG Ying, HUANG Ren-hua. Clinical study of individualized nutritional intervention in elderly patients with tumors[J]. Chinese Journal of General Practice, 2022, 20(12): 2019-2021. doi: 10.16766/j.cnki.issn.1674-4152.002759
Citation: LIAO Zhi-jun, YANG Zhi-yong, HUANG Ying, HUANG Ren-hua. Clinical study of individualized nutritional intervention in elderly patients with tumors[J]. Chinese Journal of General Practice, 2022, 20(12): 2019-2021. doi: 10.16766/j.cnki.issn.1674-4152.002759
shu

Clinical study of individualized nutritional intervention in elderly patients with tumors

doi: 10.16766/j.cnki.issn.1674-4152.002759
  • 1.

    Department of Radiotherapy, Shanghai International Medical Center, Shanghai 200120, China

Funds:

 201940274

 CKY2019-15

 CKY2019-18

  • Received Date: 2021-04-16
    Available Online: 2023-02-07
    Abstract
  •   Objective  To explore the effects of individualized nutrition intervention on nutrition, Karnofsky performance score (KPS), quality of life and life span in elderly cancer patients.  Methods  A total of 100 elderly cancer patients treated in the Department of Oncology, Chongming Branch of Xinhua Hospital Affiliated to Shanghai Jiao Tong University Medical College from January 2016 to December 2019 were selected and randomly divided into test group and control group, with 50 patients in each group. The control group adopted routine supportive treatment and palliative anti-tumor treatment according to the patient ' s condition and clinical symptoms with reference to the national comprehensive cancer network (NCCN) guidelines and the routine diagnosis and treatment. While, the test group carried out individualized nutritional intervention on the basis of the control group. Individualized nutrition intervention measures included nutrition risk screening and evaluation. According to the screening results, nutrition education and dietary guidance, oral nutrition and supplementary nutrition, enteral nutrition and parenteral nutrition intervention were given respectively. BMI, KPS and quality of life score of all patients were checked at the time of enrollment and 2 months after enrollment, and survival time of enrolled patients was calculated at 6 months after enrollment.  Results  After the intervention, the BMI and KPS scores of the two groups were statistically significant (all P < 0.05). The quality of life score of the test group [(20.75±1.67) points] was higher than that of the control group [(18.23±3.19) points, P < 0.001]. The median survival time was 172.0 days in the test group and 162.5 days in the control group, and the difference between the two groups was statistically significant (P < 0.001).  Conclusion  Individualized nutritional intervention can delay the decline of BMI, inhibit the decline of KPS score, limit the decline of quality of life and extend the life of elderly patients with tumors, which is worth promoting in clinical practice.

     

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