Volume 20 Issue 11
Nov.  2022
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Article Navigation >  Chinese Journal of General Practice  > 2022  >  20(11): 1913-1915
HU Yin-tian, HU Xi-wen. Correlation analysis of frailty syndrome with cognitive dysfunction and depression among elderly inpatients[J]. Chinese Journal of General Practice, 2022, 20(11): 1913-1915. doi: 10.16766/j.cnki.issn.1674-4152.002734
Citation: HU Yin-tian, HU Xi-wen. Correlation analysis of frailty syndrome with cognitive dysfunction and depression among elderly inpatients[J]. Chinese Journal of General Practice, 2022, 20(11): 1913-1915. doi: 10.16766/j.cnki.issn.1674-4152.002734
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Correlation analysis of frailty syndrome with cognitive dysfunction and depression among elderly inpatients

doi: 10.16766/j.cnki.issn.1674-4152.002734

  • Psychiatry Department, Mental Health Center Zhejiang University School of Medicine, Hangzhou Seventh People's Hospital, Hangzhou, Zhejiang 310013, China

Funds:

 2020KY747

  • Received Date: 2021-10-14
    Available Online: 2022-12-30
    Abstract
  •   Objective  To investigate the correlation between frailty syndrome and cognitive dysfunction and depression in elderly inpatients.  Methods  A total of 178 cases of hospitalised elderly inpatients were selected in Hangzhou Seventh People's Hospital from February 2019 to February 2020. Based on the Fried scale, the inpatients were divided into non-frailty group (42 cases), pre-frailty group (72 cases) and frailty group (64 cases). The general clinical data of the three groups were compared to analyse the correlation between frailty and cognitive dysfunction and depression as well as to explore the risk factors affecting frailty.  Results  There was statistical significance found in gender, age, number of chronic diseases, IL-6, CRP and ALB among the three groups (all P < 0.05). The incidence of cognitive dysfunction and depression in the frailty group [43 (59.72%), 31 (43.06%)] was significantly higher than that in the non-frailty group [3 (7.14%), 1 (2.38%)] and the pre-frailty group [21 (32.81%), 15 (23.43%)], all P < 0.017, and the pre-frailty group was significantly higher than that in the non-frailty group (all P < 0.017). Meanwhile, the severity of frailty were significantly positively correlated with cognitive function and the incidence of depression (r=0.138, P=0.017; r=0.163, P=0.004), respectively. Logistic regression analysis showed that age, number of chronic diseases, cognitive dysfunction and depression were independent risk factors for frailty in elderly inpatients.  Conclusion  The frailty degree of elderly inpatient frailty syndrome is positively correlated with cognitive dysfunction and depression. Therefore, old age, cognitive dysfunction, depression and several chronic diseases are independent risk factors for elderly frailty syndrome.

     

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