Volume 20 Issue 8
Aug.  2022
Turn off MathJax
Article Contents
LIN Miao, ZHOU Ping. Risk factors of postpartum hyperglycaemia in pregnant women with gestational diabetes mellitus[J]. Chinese Journal of General Practice, 2022, 20(8): 1350-1352. doi: 10.16766/j.cnki.issn.1674-4152.002594
Citation: LIN Miao, ZHOU Ping. Risk factors of postpartum hyperglycaemia in pregnant women with gestational diabetes mellitus[J]. Chinese Journal of General Practice, 2022, 20(8): 1350-1352. doi: 10.16766/j.cnki.issn.1674-4152.002594

Risk factors of postpartum hyperglycaemia in pregnant women with gestational diabetes mellitus

doi: 10.16766/j.cnki.issn.1674-4152.002594
Funds:

 2018-179

  • Received Date: 2021-09-10
  •   Objective  To investigate postpartum hyperglycaemia in pregnant women with gestational diabetes mellitus (GDM) and analyse the influencing factors of postpartum hyperglycaemia in pregnant women with GDM.  Methods  A total of 206 pregnant women with GDM who were admitted to the outpatient department of Wenchang City People ' s Hospital from May 2017 to February 2020 were selected. According to the results of 75 g oral glucose tolerance test (OGTT) at 2 months postpartum, the patients were divided into the postpartum hyperglycaemia group (54 cases) and postpartum normal blood glucose group (152 cases). The general clinical data of pregnant women in the two groups were collected, and the influencing factors of postpartum hyperglycaemia were analysed.  Results  Postpartum hyperglycaemia occurred in 54 of 206 pregnant women with GDM, and the incidence of postpartum hyperglycaemia was 26.21%. Univariate analysis showed that age, pregnancy body mass index, body mass index (BMI), macrosomia, diabetes (diabetes mellitus, DM) family history, pregnancy OGTT abnormality, using insulin therapy during pregnancy and postpartum BMI, fasting blood glucose level during pregnancy and postpartum movement were closely related to postpartum hyperglycaemia in GDM pregnant women (all P < 0.05). According to logistic regression analysis, Age (OR=2.261, P=0.023), family history of DM (OR=3.865, P=0.001), postpartum BMI (OR=2.502, P=0.020), fasting blood glucose during pregnancy (OR=2.130, P=0.029), increased number of abnormal OGTT during pregnancy (OR=4.864, P < 0.001) and insulin treatment during pregnancy (OR=3.251, P=0.001) were independent risk factors for postpartum hyperglycemia in GDM pregnant women.  Conclusion  Age, DM family history, postpartum BMI, increased OGTT abnormalities during pregnancy, fasting blood glucose during pregnancy and insulin treatment during pregnancy are independent risk factors for postpartum hyperglycaemia in GDM pregnant women. Therefore, active intervention measures should be taken clinically to prevent postpartum hyperglycaemia.

     

  • loading
  • [1]
    杨帆, 马晓娟. 妊娠期糖尿病影响因素分析及其对母婴结局影响[J]. 临床误诊误治, 2020, 33(11): 80-84. doi: 10.3969/j.issn.1002-3429.2020.11.016

    YANG F, MA X J. Influencing factors of gestational diabetes mellitus and its influence on the outcome of mother and infant[J]. Clinical Misdiagnosis & Mistherapy, 2020, 33(11): 80-84. doi: 10.3969/j.issn.1002-3429.2020.11.016
    [2]
    COSSON E, CARBILLON L, VALENSI P. High fasting plasma glucose during early pregnancy: A review about early gestational diabetes mellitus[J]. J Diabetes Res, 2017, 2017: 8921712. DOI: 10.1155/2017/8921712.
    [3]
    朱洁, 高伟娜, 刘冲, 等. 妊娠期糖尿病孕妇产后糖代谢异常的危险因素和孕中期血清硒蛋白P的预测价值[J]. 郑州大学学报(医学版), 2019, 54(5): 750-753. https://www.cnki.com.cn/Article/CJFDTOTAL-HNYK201905027.htm

    ZHU J, GAO W N, LIU C, et al. Influencing factors of abnormal postpartum glucose metabolism in pregnant women with gestational diabetes mellitus and the predictive value of serum selenium protein P in mid-pregnancy[J]. Journal of Zhengzhou University: Medical Sciences, 2019, 54(5): 750-753. https://www.cnki.com.cn/Article/CJFDTOTAL-HNYK201905027.htm
    [4]
    薛丽丽, 董金华. 妊娠期糖尿病RBP4水平与糖脂代谢指标及新生儿体重的相关性研究[J]. 中华全科医学, 2017, 15(8): 1371-1373. doi: 10.16766/j.cnki.issn.1674-4152.2017.08.029

    XUE L L, DONG J H. A correlation research of the relationship between serum retinol-binding protein 4 levels with Glucose and Lipid metabolism and body weight of the newborn in women with gestational diabetes mellitus[J]. Chinese Journal of General Practice, 2017, 15(8): 1371-1373. doi: 10.16766/j.cnki.issn.1674-4152.2017.08.029
    [5]
    IMMANUE J, SIMMONS D. Screening and treatment for early onset gestational diabetes mellitus: A systematic review and meta-analysis[J]. Curr Diab Rep, 2017, 17(11): 115. doi: 10.1007/s11892-017-0943-7
    [6]
    鲁慧, 张方琦. 降脂通心方结合阿托伐他汀对冠心病合并血脂代谢异常患者血管内皮功能和炎症因子的影响[J]. 四川中医, 2020, 38(9): 75-78. https://www.cnki.com.cn/Article/CJFDTOTAL-SCZY202009026.htm

    LU H, ZHANG F Q. Effect of Jiangzhi Tongxin decoction combined with atorvastatin on vascular endothelial function and inflammatory factors in patients with coronary heart disease complicated with dyslipidemia[J]. Journal of Sichuan of Traditional Chinese Medicine, 2020, 38(9): 75-78. https://www.cnki.com.cn/Article/CJFDTOTAL-SCZY202009026.htm
    [7]
    薛燕妮, 魏威. 高龄产妇妊娠期糖尿病发病情况及相关影响因素分析[J]. 中国妇幼保健, 2019, 34(1): 50-53. https://www.cnki.com.cn/Article/CJFDTOTAL-ZFYB201901017.htm

    XUE Y N, WEI W. Analysis of the incidence and related influencing factors of gestational diabetes mellitus in elderly women[J]. Maternal and Child Health Care of China, 2019, 34(1): 50-53. https://www.cnki.com.cn/Article/CJFDTOTAL-ZFYB201901017.htm
    [8]
    徐丹. 妊娠糖尿病患者产后血糖异常危险因素多元Logistic回归分析[J]. 湖北民族学院学报: 医学版, 2017, 34(1): 34-36. https://www.cnki.com.cn/Article/CJFDTOTAL-FBMZ201701012.htm

    XU D. Multivariate Logistic regression analysis on the risk factors of postpartum blood glucose in pregnant women with gestational diabetes mellitus[J]. Journal of Hubei University for Nationalities(Medical Edition), 2017, 34(1): 34-36. https://www.cnki.com.cn/Article/CJFDTOTAL-FBMZ201701012.htm
    [9]
    李敏怡. 妊娠期糖尿病孕妇产后血糖异常的影响因素分析[J]. 糖尿病新世界, 2018, 21(6): 40-41. https://www.cnki.com.cn/Article/CJFDTOTAL-TNBX201806021.htm

    LI M Y. Analysis of influencing factors of postpartum abnormal blood glucose in pregnant women with gestational diabetes mellitus[J]. Diabetes New World, 2018, 21(6): 40-41. https://www.cnki.com.cn/Article/CJFDTOTAL-TNBX201806021.htm
    [10]
    叶芬, 张慧莉. 影响妊娠期糖尿病孕妇产后糖代谢异常的多因素分析[J]. 湖北职业技术学院学报, 2018, 21(3): 110-112, 135. https://www.cnki.com.cn/Article/CJFDTOTAL-XGZJ201803025.htm

    YE F, ZHANG H L. The influencing factors of postpartum blood glucose abnormalities in pregnant women with gestational diabetes mellitus (GDM)[J]. Journal of Hubei Polytechnic Institute, 2018, 21(3): 110-112, 135. https://www.cnki.com.cn/Article/CJFDTOTAL-XGZJ201803025.htm
    [11]
    胡可军. 妊娠期糖尿病患者产后高血糖的危险因素研究[D]. 苏州: 苏州大学, 2018.

    HU K J. Risk factors of postpartum hyperglycemia in patients with gestational diabetes mellitus[D]. Suzhou: Soochow University, 2018.
    [12]
    董金华, 薛丽丽. 妊娠期糖尿病孕妇血清和脐血RBP4与胎儿体重的关系[J]. 中华全科医学, 2016, 14(10): 1786-1788. doi: 10.16766/j.cnki.issn.1674-4152.2016.10.057

    DONG J H, XUE L L. Relationship between serum and cord blood RBP4 and fetal weight in pregnant women with gestational diabetes mellitus[J]. Chinese Journal of General Practice, 2016, 14(10): 1786-1788. doi: 10.16766/j.cnki.issn.1674-4152.2016.10.057
    [13]
    汪艳丽. 空腹血糖、糖化血清蛋白和糖化血红蛋白在2型糖尿病治疗监测中的应用[J]. 国际检验医学杂志, 2017, 38(16): 2320-2322. https://www.cnki.com.cn/Article/CJFDTOTAL-GWSQ201716058.htm

    WANG Y L. Application of fasting blood glucose, glycosylated serum protein and glycosylated hemoglobin in monitoring the treatment of type 2 diabetes mellitus[J]. International Journal of Laboratory Medicine, 2017, 38(16): 2320-2322. https://www.cnki.com.cn/Article/CJFDTOTAL-GWSQ201716058.htm
    [14]
    刘阳. 妊娠期糖尿病患者产后早期糖代谢转归的研究[D]. 泸州: 西南医科大学, 2020.

    LIU Y. Study on the outcome of early postpartum glucose metabolism in gestational diabetes mellitus[D]. Luzhou: Southwest Medical University, 2020.
    [15]
    李爱玲, 韩晓华, 杨艺君, 等. 妊娠期糖尿病孕妇产后糖代谢异常相关因素分析[J]. 中国妇幼保健, 2018, 33(21): 4860-4863. https://www.cnki.com.cn/Article/CJFDTOTAL-ZFYB201821019.htm

    LI A L, HAN X H, YANG Y J. Analysis of related factors of abnormal glucose metabolism in pregnant women with gestational diabetes mellitus[J]. Maternal and Child Health Care of China, 2018, 33(21): 4860-4863. https://www.cnki.com.cn/Article/CJFDTOTAL-ZFYB201821019.htm
    [16]
    文立莲. 妊娠期糖尿病孕妇产后血糖异常危险因素分析[J]. 医学理论与实践, 2020, 33(2): 275-276. https://www.cnki.com.cn/Article/CJFDTOTAL-YXLL202002053.htm

    WEN L L. Risk factors of postpartum abnormal blood glucose in pregnant women with gestational diabetes mellitus[J]. The Journal of Medical Theory and Practice, 2020, 33(2): 275-276. https://www.cnki.com.cn/Article/CJFDTOTAL-YXLL202002053.htm
    [17]
    王玲. 妊娠期糖尿病孕妇产后血糖异常相关危险因素Logistic回归分析[J]. 中国处方药, 2019, 17(9): 4-5. https://www.cnki.com.cn/Article/CJFDTOTAL-ZGCF201909006.htm

    WANG L. Logistic investigate the relevant risk factors for postpartum blood glucose abnormal in pregnant women[J]. Journal of China Prescription Drug, 2019, 17(9): 4-5. https://www.cnki.com.cn/Article/CJFDTOTAL-ZGCF201909006.htm
  • 加载中

Catalog

    通讯作者: 陈斌, bchen63@163.com
    • 1. 

      沈阳化工大学材料科学与工程学院 沈阳 110142

    1. 本站搜索
    2. 百度学术搜索
    3. 万方数据库搜索
    4. CNKI搜索

    Tables(3)

    Article Metrics

    Article views (515) PDF downloads(5) Cited by()
    Proportional views
    Related

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return
    Return