Volume 20 Issue 8
Aug.  2022
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Article Navigation >  Chinese Journal of General Practice  > 2022  >  20(8): 1315-1318
YUAN Chang-hong, WU Xiao-yu, LIU Qun, ZHANG Lu, ZHU Ying-chun. Effect of pre-stroke physical activity on pial collateral circulation and patient prognosis[J]. Chinese Journal of General Practice, 2022, 20(8): 1315-1318. doi: 10.16766/j.cnki.issn.1674-4152.002585
Citation: YUAN Chang-hong, WU Xiao-yu, LIU Qun, ZHANG Lu, ZHU Ying-chun. Effect of pre-stroke physical activity on pial collateral circulation and patient prognosis[J]. Chinese Journal of General Practice, 2022, 20(8): 1315-1318. doi: 10.16766/j.cnki.issn.1674-4152.002585
shu

Effect of pre-stroke physical activity on pial collateral circulation and patient prognosis

doi: 10.16766/j.cnki.issn.1674-4152.002585

  • Department of Neurology, the Second People's Hospital of Anhui Province, Hefei, Anhui 230041, China

Funds:

 2018SEYL029

  • Received Date: 2021-11-21
    Available Online: 2022-09-26
    Abstract
  •   Objective  To determine the effect of pre-stroke physical activity level on pial collateral circulation and prognosis in patients with acute anterior circulation cerebral infarction.  Methods  Patients with acute anterior circulation cerebral infarction admitted to the Department of Neurology, rhe Second People's Hospital of Anhui Province from January 2017 to June 2020 were enrolled. The regional leptomeningeal score (rLMC) evaluated by CT angiography (CTA) was used to semi-quantitatively evaluate the patients ' pial collateral circulation. The modern Saltin-Grimby Physical Activity Level Scale (SGPALS) was used to quantitatively evaluate the physical activity level of patients before stroke. The modified Rankin Scale (mRS) score was used to assess the patients ' ability to take care of himself at 3 months onset. The difference in rLMC between patients with different physical activity levels and the effect on 90-day mRS score were compared.  Results  A total of 157 patients were enrolled, including 72 patients in the low exercise group and 85 patients in the high exercise group. The baseline systolic blood pressure, baseline NIHSS score and 3-month mRS score in the high exercise group were lower than those in the low exercise group (P values were 0.001, 0.039, < 0.001, respectivey), and the rLMC score was higher in the high exercise group than in the low exercise group (P=0.023). The prognosis of 99 patients was good (mRS≤2) and 58 patients was poor (mRS > 2) after 3 months onset. The SGPALS score of the good prognosis group was higher than that of the poor prognosis group (P < 0.001), and the rLMC score of the good prognosis group was higher than that of the poor prognosis group (P < 0.001). The previous statin use rate of the good prognosis group was higher than that of the poor prognosis group (P=0.041). Multivariate logistic regression analysis showed that SGPALS score and rLMC score were protective factors of good prognosis (OR=1.455, 1.181, P=0.043, 0.003, respectively). Previous diabetes history and baseline NIHSS score were unfavourable factors for good prognosis (OR=0.366, 0.899, P=0.027, 0.023, respectively).  Conclusion  Pre-stroke physical activity can improve the pial collateral circulation of patients with acute anterior circulation cerebral infarction and the clinical prognosis for 3 months.

     

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