Volume 20 Issue 3
Mar.  2022
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LU Yao, ZHANG Li, QIAN Jing-yu, SHI Ao, GE Yu-yao. Clinical observation of DSA combined with ultrasound-guided treatment of body superficial venous malformation[J]. Chinese Journal of General Practice, 2022, 20(3): 375-378. doi: 10.16766/j.cnki.issn.1674-4152.002356
Citation: LU Yao, ZHANG Li, QIAN Jing-yu, SHI Ao, GE Yu-yao. Clinical observation of DSA combined with ultrasound-guided treatment of body superficial venous malformation[J]. Chinese Journal of General Practice, 2022, 20(3): 375-378. doi: 10.16766/j.cnki.issn.1674-4152.002356

Clinical observation of DSA combined with ultrasound-guided treatment of body superficial venous malformation

doi: 10.16766/j.cnki.issn.1674-4152.002356
Funds:

 KJ2021A0804

  • Received Date: 2021-03-28
    Available Online: 2022-08-13
  •   Objective  To compare the efficacy and safety of digital subtraction angiography (DSA) combined with ultrasound-guided therapy in the treatment of superficial venous malformations.  Methods  Thirty cases of superficial venous malformation admitted to the Department of Orthopaedics of the First Affiliated Hospital of Bengbu Medical College from January 2012 to December 2020 were retrospectively treated with ultrasound-guided direct percutaneous puncture injection of sclerotherapy. According to the results of ultrasound and magnetic resonance examination, the patients were divided into group A and group B. Group A had cavitary lesion with no important peripheral blood vessels and nerves. In group B, the lesions were dilated, which were deeper or adjacent to important neurovascular and skeletal lesions. A total of 19 patients, including 6 males and 13 females, with an average age of 25 (6, 32) years, were enrolled in group A. In group B, 11 patients, including 4 males and 7 females, with an average age of 17 (11, 54) years, were treated with DSA combined with ultrasound guidance. After treatment, the patients were followed up for 3-12 months to compare the clinical effects and postoperative adverse reactions between group A and group B.  Results  In group A, 3 cases were cured, 10 cases had significant remission, 5 cases had partial remission, and 1 case was ineffective. The total effective rate was 94.7%(18/19), and the cure rate 15.79%(3/19). An average of 2.40 injections were given. In group B, 6 cases were cured, 2 cases had significant remission, 3 cases had partial remission, and 0 cases were ineffective. The effective rate was 100.00%, and the cure rate was 54.55%(6/11). Each patient was injected 1.37 times on average. The main adverse reactions were local soft tissue swelling and pain. After symptomatic treatment, such as local ice compress, improvement of microcirculation and intravenous dexamethasone, the symptoms were relieved. No serious complications such as pulmonary embolism or cardio-cerebrovascular accident were found, and no gross haematuria or haemoglobinuria was found.  Conclusion  Under imaging guidance, the application of lauromacrogol combined with pingyangmycin in the treatment of somatic venous malformations is a safe and effective method. For malformed veins with the largest diameter of the lesion >5 cm, DSA-guided treatment can result in higher cure rate.

     

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