Analysis of factors related to cervical lymph node metastasis in 208 patients with papillary thyroid carcinoma

GUO Bin; CHEN Rui; WANG Sheng-ying; PENG Mei

doi:10.16766/j.cnki.issn.1674-4152.002310

Volume 20 Issue 2

Feb. 2022

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GUO Bin, CHEN Rui, WANG Sheng-ying, PENG Mei. Analysis of factors related to cervical lymph node metastasis in 208 patients with papillary thyroid carcinoma[J]. Chinese Journal of General Practice, 2022, 20(2): 195-198, 262. doi: 10.16766/j.cnki.issn.1674-4152.002310

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GUO Bin, CHEN Rui, WANG Sheng-ying, PENG Mei. Analysis of factors related to cervical lymph node metastasis in 208 patients with papillary thyroid carcinoma[J]. Chinese Journal of General Practice, 2022, 20(2): 195-198, 262. doi: 10.16766/j.cnki.issn.1674-4152.002310

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Analysis of factors related to cervical lymph node metastasis in 208 patients with papillary thyroid carcinoma

doi: 10.16766/j.cnki.issn.1674-4152.002310

GUO Bin¹
, CHEN Rui¹
, WANG Sheng-ying²
, PENG Mei^{3
,
,}

1.
Ultrasonic Department, the First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui 230031, China

Funds:

201904A07020068

Received Date: 2021-04-16
Available Online: 2022-03-04

Abstract

Abstract

Objective To explore the related factors of cervical lymph node metastasis in patients with papillary thyroid carcinoma (PTC), so as to provide the basis for clinical treatment decision-making and prognosis evaluation. Methods The ultrasonic, pathological and clinical data of 208 cases with PTC confirmed by pathology in the First Affiliated Hospital of the University of Science and Technology of China (Anhui Provincial Hospital) from June 2019 to December 2019 were collected. Univariate and multivariate logistic regression analysis was used to analyse the related factors of the cervical lymph node metastasis group and non-metastasis group. Results Amongst the 208 patients, 126 had cervical lymph node metastasis, and the rate of metastasis was 60.6%. A significant difference was observed in the cervical lymph node metastasis rate amongst different gender, age, tumour location, tumour length and diameter, abnormal lymph nodes, tumour aspect ratio >1, multifocal lesions, bilateral lesions, capsule invasion, nodal calcification and PTC patients with nodular goitre (all P < 0.05). The Results of multivariate logistic analysis showed that female (OR=0.386) was a protective factor for cervical lymph node metastasis in patients with PTC, and tumour located in the lower pole(OR=3.057), abnormal lymph nodes in ultrasound (OR=6.277) and multifocal lesions (OR=2.889) were independent risk factors for cervical lymph node metastasis in patients with PTC. Conclusion Cervical lymph node metastasis in PTC patients is closely related to many factors. Paying attention to and analysing these factors have important clinical significance for clinical staging, treatment decision-making and prognosis evaluation.
- Thyroid papillary carcinoma,
- Cervical lymph node metastasis,
- Related factors

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Analysis of factors related to cervical lymph node metastasis in 208 patients with papillary thyroid carcinoma

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