Volume 19 Issue 12
Dec.  2021
Turn off MathJax
Article Contents
Article Navigation >  Chinese Journal of General Practice  > 2021  >  19(12): 2115-2118
HUANG Zhen, ZHANG Di, SONG Shuang-lin, BIAN Zhen-yu. Efficacy of acupoint embedding thread combined with warm acupuncture in treating patients with knee osteoarthritis[J]. Chinese Journal of General Practice, 2021, 19(12): 2115-2118. doi: 10.16766/j.cnki.issn.1674-4152.002250
Citation: HUANG Zhen, ZHANG Di, SONG Shuang-lin, BIAN Zhen-yu. Efficacy of acupoint embedding thread combined with warm acupuncture in treating patients with knee osteoarthritis[J]. Chinese Journal of General Practice, 2021, 19(12): 2115-2118. doi: 10.16766/j.cnki.issn.1674-4152.002250
shu

Efficacy of acupoint embedding thread combined with warm acupuncture in treating patients with knee osteoarthritis

doi: 10.16766/j.cnki.issn.1674-4152.002250

  • Department of Acupuncture, Affiliated Hangzhou First People's Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang 310006, China

Funds:

 2019ZA091

  • Received Date: 2020-11-02
    Available Online: 2022-03-02
    Abstract
  •   Objective  To investigate the efficacy of acupoint embedding thread combined with warm acupuncture in treating patients with knee osteoarthritis and its effect on the levels of serum interleukin (IL)-1, IL-6 and tumour necrosis factor (TNF)-α.  Methods  One hundred twenty patients with knee osteoarthritis admitted in our hospital from September 2017 to July 2020 were selected and divided into control group and observation group with 60 patients in each group using the random number table method. The control group was treated with diclofenac sodium sustained-release tablets, whereas the observation group was treated with acupoint embedding combined with warm acupuncture. The course of treatment of the two groups was 4 weeks. The visual analogue scale (VAS), scores of Lysholm scale (LKSS), WOMAC indexes, symptoms of traditional Chinese medicine, clinical efficacy and serum levels of IL-1, IL-6 and TNF-α were compared between the two groups.  Results  After treatment, the VAS [(1.36±0.17) points], scores of LKSS [(76.13±8.46) points] and WOMAC indexes [(2.72±0.34) points, (0.94±0.14) points, (15.40±2.22) points] in the observation group were significantly higher than those in the control group [VAS (2.81±0.43) points, scores of LKSS (62.01±7.75) points, WOMAC indexes (4.31±0.52) points, (1.65±0.22) points, (20.38±2.46) points; all P < 0.001], and symptoms of traditional Chinese medicine in the observation group were significantly higher than those in the control group (all P < 0.001). The total effective rate of the observation group was significantly higher than that of the control group (P < 0.05). After treatment, the improvement of serum IL-1 [(8.21±1.25) ng/L], IL-6 [(33.61±4.46) ng/L] and TNF-α [(12.09±1.77) ng/L] in the observation group were significantly better than those in the control group [IL-1 (12.13±1.65) ng/L, IL-6 (54.81±6.03) ng/L, TNF-α (15.40±2.51) ng/L, all P < 0.001].  Conclusion  The efficacy of acupoint embedding thread combined with warm acupuncture in treating patients with knee osteoarthritis is significant, which shows potential application in clinic.

     

    • FullText(HTML)
  • loading
    • References(18)
  • [1]
    郑陶, 许治国, 许志宇, 等. 桃红二膝汤联合双醋瑞因治疗膝骨关节炎的临床疗效[J]. 中华中医药学刊, 2019, 37(12): 3070-3072. https://www.cnki.com.cn/Article/CJFDTOTAL-ZYHS201912062.htm
    [2]
    张其镇, 苗雨, 王大力, 等. 独活寄生汤配合温针灸治疗风寒湿痹型膝骨关节炎患者的疗效及对血清疼痛介质、炎症介质、白三烯的影响[J]. 中国实验方剂学杂志, 2018, 24(18): 153-158. https://www.cnki.com.cn/Article/CJFDTOTAL-ZSFX201818025.htm
    [3]
    潘峰, 朱建华. 朱良春益肾壮督、蠲痹通络法治疗痹证之奇经学说思想探析[J]. 中医杂志, 2016, 57(23): 1993-1995. https://www.cnki.com.cn/Article/CJFDTOTAL-ZZYZ201623004.htm
    [4]
    潘媛媛, 唐侠军, 崔文强, 等. 穴位埋线治疗膝骨关节炎临床观察[J]. 中国中医药现代远程教育, 2020, 18(9): 90-92. doi: 10.3969/j.issn.1672-2779.2020.09.036
    [5]
    王晓玲, 王芗斌, 侯美金, 等. 温针灸治疗膝骨关节炎: 随机对照研究[J]. 中国针灸, 2017, 37(5): 457-462. https://www.cnki.com.cn/Article/CJFDTOTAL-ZGZE201705001.htm
    [6]
    童培建. 膝骨关节炎中西医结合诊疗指南[J]. 中华医学杂志, 2018, 98(45): 3653-3658. doi: 10.3760/cma.j.issn.0376-2491.2018.45.005
    [7]
    LAKKIREDDY M, BEDARAKOTA D, VIDYASAGAR J, et al. Correlation among radiographic, arthroscopic and pain criteria for the diagnosis of knee osteoarthritis[J]. J Clin Diagn Res, 2015, 9(12): RC04-RC07. https://pubmed.ncbi.nlm.nih.gov/26816954/
    [8]
    黄吉利, 罗明, 潘捷, 等. 应用VAS和KSS分析关节镜滑膜切除术后疼痛及膝关节功能[J]. 基因组学与应用生物学, 2017, 36(4): 1435-1439. https://www.cnki.com.cn/Article/CJFDTOTAL-GXNB201704028.htm
    [9]
    林志达. Kujala和Lysholm量表评估膝关节前交叉韧带术后功能信度及其相关性研究[J]. 按摩与康复医学, 2015, 6(5): 42-44. https://www.cnki.com.cn/Article/CJFDTOTAL-AMYD201505023.htm
    [10]
    BELLAMY N. Pain assessment in osteoarthritis: Experience with the WOMAC osteoarthritis index[J]. Semin Arthritis Rheum, 1989, 18(4): 14-17. doi: 10.1016/0049-0172(89)90010-3
    [11]
    郑筱萸. 中药新药临床研究指导原则(试行)[S]. 北京: 中国医药科技出版社, 2002: 349-352.
    [12]
    张里援, 陈湘宜, 吴惠明. 舒筋松腱剂治疗晚期膝骨关节炎的效果及对血清bFGF水平和膝关节功能恢复的影响[J]. 中华全科医学, 2021, 19(2): 221-223, 273. https://www.cnki.com.cn/Article/CJFDTOTAL-SYQY202102016.htm
    [13]
    李凤国, 张兰云, 周志洁, 等. 关节内注射复方双氯芬酸钠治疗中重度骨关节炎的临床研究[J]. 中国中医骨伤科杂志, 2019, 27(7): 23-26. https://www.cnki.com.cn/Article/CJFDTOTAL-ZGZG201907006.htm
    [14]
    李长香, 程发峰, 王雪茜, 等. 叶天士从络病论治痹证研究[J]. 中华中医药杂志, 2016, 31(5): 1758-1761. https://www.cnki.com.cn/Article/CJFDTOTAL-BXYY201605046.htm
    [15]
    林陈娟, 王兴民, 叶青青. 穴位埋线联合参苓白术散加减治疗单纯性肥胖脾虚湿阻证30例[J]. 浙江中医杂志, 2020, 55(3): 217-218. doi: 10.3969/j.issn.0411-8421.2020.03.036
    [16]
    刘艳伟, 孟爱霞, 胡华, 等. 火针高选择性去隐神经关节支及腓总神经关节支联合塞来昔布口服对膝骨关节炎患者WOMAC评分及TNF-α的影响[J]. 河北医学, 2017, 23(8): 1242-1245. doi: 10.3969/j.issn.1006-6233.2017.08.003
    [17]
    邝高艳, 严可, 柴爽, 等. 加味独活寄生合剂治疗膝骨关节炎临床疗效及对关节液中IL-1, IL-6, TNF-α及NO的影响[J]. 中国实验方剂学杂志, 2017, 23(1): 174-178. https://www.cnki.com.cn/Article/CJFDTOTAL-ZSFX201701030.htm
    [18]
    林晓航, 唐剑邦, 吴宇峰, 等. 关节镜清理术联合关节内注射透明质酸钠对膝骨关节炎患者TNF-α、IL-6和IL-1β的影响[J]. 国际检验医学杂志, 2017, 38(23): 3335-3337. doi: 10.3969/j.issn.1673-4130.2017.23.044
    • Relative Articles
    • Supplements(0)
    • Cited By
  • 加载中

Catalog

    通讯作者: 陈斌, bchen63@163.com
    • 1. 

      沈阳化工大学材料科学与工程学院 沈阳 110142

    1. 本站搜索
    2. 百度学术搜索
    3. 万方数据库搜索
    4. CNKI搜索

    Tables(6)

    Get Citation
    PDF
    XML

    Article Metrics

    Article views (309) PDF downloads(9) Cited by()
    Proportional views
    Related

    Address：No. 287, Changhuai Road, Bengbu, Anhui Province, 233004, P.R.ChinaphoneNo：0552-3066635； 0552-3051890Email：zhqkyx@163.com

    Copyright © Chinese Journal of General Practice皖ICP备2020018345号-2

    Supported by: Beijing Renhe Information Technology Co., Ltd.    

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return
    Return