Volume 19 Issue 8
Aug.  2021
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Article Navigation >  Chinese Journal of General Practice  > 2021  >  19(8): 1300-1302,1329
ZHNAG Zhi-hua, YU Guo-feng. Clinical study of thromboelastography in the diagnosis of traumatic coagulopathy after craniocerebral injury[J]. Chinese Journal of General Practice, 2021, 19(8): 1300-1302,1329. doi: 10.16766/j.cnki.issn.1674-4152.002045
Citation: ZHNAG Zhi-hua, YU Guo-feng. Clinical study of thromboelastography in the diagnosis of traumatic coagulopathy after craniocerebral injury[J]. Chinese Journal of General Practice, 2021, 19(8): 1300-1302,1329. doi: 10.16766/j.cnki.issn.1674-4152.002045
shu

Clinical study of thromboelastography in the diagnosis of traumatic coagulopathy after craniocerebral injury

doi: 10.16766/j.cnki.issn.1674-4152.002045
  • 1.

    Department of Neurosurgery, Taizhou Hospital of Traditional Chinese Medicine, Taizhou, Zhejiang 318000, China

Funds:

 2017KY697

  • Received Date: 2021-04-01
    Available Online: 2022-02-16
    Abstract
  •   Objective  To observe the clinical effect and prognostic value of thromboelastography (TEG) in the diagnosis of traumatic coagulopathy after craniocerebral injury.   Methods   Total 200 patients with acute craniocerebral injury in our hospital were selected as the research objects from December 2018 to February 2021. All patients were detected by routine coagulation test and TEG test. The detection of traumatic coagulopathy by routine coagulation test and TEG test at different time after craniocerebral injury was statistically analyzed. The TEG indexes of patients with craniocerebral injury at different time and different prognosis levels were compared, and the related risk factors of death in patients with traumatic coagulopathy were analyzed.   Results   ]The detection rate of TEG in 4 hours and 12 hours of traumatic coagulopathy (34.50% and 63.00%) after craniocerebral injury was significantly higher than that of conventional coagulopathy (18.50% and 40.50%, χ2=13.143, 20.275, P < 0.001), and the incidence of traumatic coagulopathy in patients with severe craniocerebral injury (84.81%) was significantly higher than that in patients with non-severe craniocerebral injury (48.76%, χ2=26.647, P < 0.001). The R and K values at 12 h after injury were significantly higher than those at 4 h after injury, while the angle and Ma values were significantly lower than those at 4 h after injury (P < 0.001). There was no significant difference between the R value of the dead patients and the survival patients (t=1.583, P=0.116), but the K value was significantly higher than the survival patients, and the angle value and MA value were significantly lower than the survival patients (P < 0.001). The MA value was the related risk factor of death in patients with traumatic coagulopathy.   Conclusion   TEG detection can dynamically monitor the early changes of coagulation function in patients with craniocerebral injury, effectively identify the occurrence of traumatic coagulopathy, and can be used for early evaluation of prognosis of patients with traumatic coagulopathy after craniocerebral injury.

     

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