Volume 19 Issue 7
Jul.  2021
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Article Navigation >  Chinese Journal of General Practice  > 2021  >  19(7): 1243-1247
LU Hong, GENG Chun-hua, XIAO Bin, WANG Yi, XU Yang. Effects of early systematic care on patients with esophageal cancer undergoing radiotherapy[J]. Chinese Journal of General Practice, 2021, 19(7): 1243-1247. doi: 10.16766/j.cnki.issn.1674-4152.002031
Citation: LU Hong, GENG Chun-hua, XIAO Bin, WANG Yi, XU Yang. Effects of early systematic care on patients with esophageal cancer undergoing radiotherapy[J]. Chinese Journal of General Practice, 2021, 19(7): 1243-1247. doi: 10.16766/j.cnki.issn.1674-4152.002031
shu

Effects of early systematic care on patients with esophageal cancer undergoing radiotherapy

doi: 10.16766/j.cnki.issn.1674-4152.002031

  • Department of Oncology, the Hefei Binhu Hospital, Hefei, Anhui 230601, China

Funds:

 S20193400016

 hwk2017zd013

  • Received Date: 2020-09-25
    Available Online: 2022-02-16
    Abstract
  •   Objective  To investigate the effects of early systematic nursing care on patients suffering from esophageal carcinoma and receiving radiotherapy.  Methods  From January 2018 to April 2020, we enrolled 46 patients with esophageal carcinoma and divided into two groups of 23 individuals at random. Usual care or early systematic nursing care was adopted for the control or study group.The nutrition index, quality of life, serum inflammatory factors, occurrence of radiation esophagitis (RE) and pneumonia (RP) were the indicators we used for comparison.  Results  All pieces of baseline information showed no obvious distinction between the two groups (all P>0.05). The incidence of RE was 8.70% and dramatically attenuated in patients who received early systematic nursing, as compared with that in the control group (39.13%, P < 0.05). As for RP, the incident rate was 4.35% in the study group and lower than that in the control (17.39%), but no distinct difference was observed (P>0.05). Patients who received early systematic nursing had remarkably lower serum IL-6, TGF-β, S100A8 and IL-10 levels than patients who received usual nursing (all P < 0.05). Quality of life with SF-36 showed that the total score of the study group [(598.30±143.20) points] was considerably improved when compared with that of the control group [(417.00±200.58) points]. Meanwhile, BMI, Hb, ALB and Lym in patients who received early systematic nursing were higher than those in the control group (all P < 0.05).  Conclusion  During radio therapy of patients with esophageal cancer, the early systematic nursing can improve nutritional status and inhibit the release of inflammatory cytokines and may thus be paramount in the suppression of radiation-induced esophagitis and improvement of patients' quality of life.

     

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