Volume 19 Issue 7
Jul.  2021
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Article Navigation >  Chinese Journal of General Practice  > 2021  >  19(7): 1239-1242
LI Rui-yun, LI Qiong. Application effect of individualised nursing combined with cluster nursing in edaravone treatment of acute paraquat poisoning[J]. Chinese Journal of General Practice, 2021, 19(7): 1239-1242. doi: 10.16766/j.cnki.issn.1674-4152.002030
Citation: LI Rui-yun, LI Qiong. Application effect of individualised nursing combined with cluster nursing in edaravone treatment of acute paraquat poisoning[J]. Chinese Journal of General Practice, 2021, 19(7): 1239-1242. doi: 10.16766/j.cnki.issn.1674-4152.002030
shu

Application effect of individualised nursing combined with cluster nursing in edaravone treatment of acute paraquat poisoning

doi: 10.16766/j.cnki.issn.1674-4152.002030
  • 1.

    Emergency Department, the Third Affiliated Hospital of Xinxiang Medical College, Xinxiang, Henan 453000, China

Funds:

 17A320027

  • Received Date: 2020-08-25
    Available Online: 2022-02-16
    Abstract
  •   Objective  To explore the application effect of individualised nursing combined with cluster nursing in the treatment of acute paraquat poisoning with edaravone.  Methods  Fifty-four patients with acute paraquat poisoning admitted at the Third Affiliated Hospital of Xinxiang Medical College from January 2015 to January 2020 were selected and treated with edaravone. They were randomly divided into the control group (27 cases, using personalised nursing) and observation group (27 cases, using personalised nursing combined with cluster nursing). The levels of tumour necrosis factor (TNF)-α, ALT, Cr and serum interleukin (IL)-18 were compared between the two groups before and after nursing. The 28-day survival rate and mortality of the two groups were observed and recorded.  Results  Compared with the control group, the levels of TNF-α and IL-18 in the observation group were lower after nursing, and the difference was statistically significant [(74.75±8.58) ng/L vs. (112.42±12.39) ng/L, (145.42±13.85) ng/L vs. (164.57±15.34) ng/L, t=12.988, 4.815, all P < 0.05]. No significant difference was observed in ALT and Cr levels between the two groups before nursing (all P>0.05); compared with the control group, the levels of ALT and Cr in the observation group were lower after nursing, and the difference was statistically significant [(122.82±15.65) U/mL vs. (236.15±28.58) U/mL, (138.56±15.77) μmol/L vs. (181.36±19.34) μmol/L, t=18.073, 8.912, all P < 0.05]. The 28-day survival rate of patients in the observation group was 48.15%, and that of patients in the control group was 22.22%. Compared with the control group, the 28-day survival rate of patients in the observation group was higher, and the difference was statistically significant (χ2=3.979, P=0.046).  Conclusion  Edaravone treatment and combined nursing (individualised nursing+cluster nursing) can effectively improve the related biochemical indexes such as TNF-α, serum IL-18, ALT and Cr and increase the survival rate and prognosis of patients with acute paraquat poisoning.

     

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