Volume 19 Issue 7
Jul.  2021
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Article Navigation >  Chinese Journal of General Practice  > 2021  >  19(7): 1175-1178
SHI Jie, HU Yin-tian, CHENG Wei. The risk factors and correlation with cognitive function for relapse of alcohol dependence[J]. Chinese Journal of General Practice, 2021, 19(7): 1175-1178. doi: 10.16766/j.cnki.issn.1674-4152.002014
Citation: SHI Jie, HU Yin-tian, CHENG Wei. The risk factors and correlation with cognitive function for relapse of alcohol dependence[J]. Chinese Journal of General Practice, 2021, 19(7): 1175-1178. doi: 10.16766/j.cnki.issn.1674-4152.002014
shu

The risk factors and correlation with cognitive function for relapse of alcohol dependence

doi: 10.16766/j.cnki.issn.1674-4152.002014

  • Department of Psychiatry, Hangzhou Seventh People's Hospital, Mental Health Center Zhejiang University School of Medicine, Hangzhou, Zhejiang 310013, China

Funds:

 2020KY746

  • Received Date: 2020-12-19
    Available Online: 2022-02-16
    Abstract
  •   Objective  To investigate the risk factors of alcohol dependence and to evaluate the cognitive function of patients with alcohol dependence and to explore the relationship between cognitive function impairment and rehydration.  Methods  Total 85 patients with alcohol dependence who were given abstinence treatment in Hangzhou Seventh People's Hospital from June 2018 to June 2019 were selected as the research objects. According to whether alcohol dependence occurred again within one year after abstinence, they were divided into the relapse group (52 cases) and the non-relapse group (33 cases). The executive function, memory function and attention ability of the two groups were compared to analyze the risk factors of alcohol dependence relapse.  Results  There were statistically significant differences between the relapse group and the non-relapse group in terms of alcohol consumption, marital status and emotional symptoms before treatment (all P < 0.05). The emotional expression, intimacy, independence, organization, control and entertainment of the patients in the relapse group were significantly lower than those in the non- relapse group (all P < 0.05). The total number of executive forces WCST responses, the number of completed classification and the number of correct responses in the relapse group were significantly lower than those in the non-relapse group (all P < 0.05). The scores of memory S/VM, SS and DS in the relapse group were significantly lower than those in the non- relapse group (all P < 0.01), while there was no significant difference between the VM scores and those in the non- relapse group (P>0.05). The scores of attention DST and CPT-IP were significantly lower in the rehydration group than those in the non-rehydration group (all P < 0.01). Non-conditional logistic regression analysis showed that higher alcohol consumption, associated emotional symptoms, lower independence and affinity density, poor control and organization, and poor attention and executive ability were risk factors for alcohol dependence.  Conclusion  Heavy drinking, emotional symptoms, lack of organization in family environment, independence and affinity, lack of executive ability and attention are risk factors affecting patients' relapse, which should be paid attention to clinically.

     

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