Volume 19 Issue 7
Jul.  2021
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Article Navigation >  Chinese Journal of General Practice  > 2021  >  19(7): 1121-1124
YAO Chao, ZHANG Deng-yong, SUN Wan-liang, LU Zheng. Application of ICG fluorescence imaging in laparoscopic hepatectomy for primary liver cancer[J]. Chinese Journal of General Practice, 2021, 19(7): 1121-1124. doi: 10.16766/j.cnki.issn.1674-4152.002000
Citation: YAO Chao, ZHANG Deng-yong, SUN Wan-liang, LU Zheng. Application of ICG fluorescence imaging in laparoscopic hepatectomy for primary liver cancer[J]. Chinese Journal of General Practice, 2021, 19(7): 1121-1124. doi: 10.16766/j.cnki.issn.1674-4152.002000
shu

Application of ICG fluorescence imaging in laparoscopic hepatectomy for primary liver cancer

doi: 10.16766/j.cnki.issn.1674-4152.002000

  • Department of Hepatobiliary Surgery, the First Affiliated Hospital of Bengbu Medical College, Bengbu, Anhui 233004, China

Funds:

 1808085QH288

  • Received Date: 2020-11-30
    Available Online: 2022-02-16
    Abstract
  •   Objective  To study the application value of indocyanine green (ICG) molecular fluorescence imaging in laparoscopic hepatectomy for primary liver cancer.  Methods  The clinical and pathological data of 56 patients with primary liver cancer who underwent ICG fluorescence laparoscopic hepatectomy in the Department of Hepatobiliary Surgery of the First Affiliated Hospital of Bengbu Medical College from December 2018 to September 2020 were analysed retrospectively. The operative methods, the methods of preoperative staining, the characteristics of intraoperative fluorescence tumour development, the detection of new lesions and the pathological results of tumour after operation were statistically analysed.  Results  All patients successfully completed hepatectomy under ICG fluorescence laparoscopy without conversion to laparotomy. New suspicious lesions were found in 9 patients under fluorescence imaging. Pathological examination of intraoperative rapid frozen section showed 4 cases of hepatocellular carcinoma, 1 case of inflammatory changes and 4 cases of sclerotic nodules. Amongst the 9 patients, eight cases were complicated with liver cirrhosis. During the operation, staining failed in 10 patients due to severe liver cirrhosis or the presence of communicating branches. Staining failed in 8 patients who were injected with ICG before operation and 2 patients who received anti-staining during operation. The patients of Child-Pugh grade A could obtain a good development effect 2 or 3 days before operation, whereas those of grade B had the best tumour development under fluorescence 5 days before operation. All patients had no serious complications and recovered well.  Conclusion  The development of ICG fluorescence imaging technology provides surgeons with a simple and effective navigation method that can accurately locate the tumour and resection boundary and help to find superficial small lesions. However, how to define the degree of liver cirrhosis and injection time still need to be discussed.

     

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