Volume 19 Issue 6
Jun.  2021
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Article Navigation >  Chinese Journal of General Practice  > 2021  >  19(6): 959-963
CHEN Yu-rong, DUAN Xiao-kai, LIU Chun-fan, YANG Xiao, JIANG Yan-li, ZHANG Zhen-xiang, DU Shao-fei. Analysis of influencing factors and pregnancy outcomes of macrosomia among pregnant women with diabetes in a hospital in Zhengzhou City from 2014 to 2018[J]. Chinese Journal of General Practice, 2021, 19(6): 959-963. doi: 10.16766/j.cnki.issn.1674-4152.001960
Citation: CHEN Yu-rong, DUAN Xiao-kai, LIU Chun-fan, YANG Xiao, JIANG Yan-li, ZHANG Zhen-xiang, DU Shao-fei. Analysis of influencing factors and pregnancy outcomes of macrosomia among pregnant women with diabetes in a hospital in Zhengzhou City from 2014 to 2018[J]. Chinese Journal of General Practice, 2021, 19(6): 959-963. doi: 10.16766/j.cnki.issn.1674-4152.001960
shu

Analysis of influencing factors and pregnancy outcomes of macrosomia among pregnant women with diabetes in a hospital in Zhengzhou City from 2014 to 2018

doi: 10.16766/j.cnki.issn.1674-4152.001960
  • 1.

    Hanghaidonglu Community Health Service Centre of Zhengzhou First People's Hospital, Zhengzhou, He'nan 450000, China

Funds:

 2018020734

 2018020730

 2018020733

 Wjlx2017221

  • Received Date: 2020-09-30
    Available Online: 2022-02-16
    Abstract
  •   Objective  To analyse the influencing factors and pregnancy outcomes of fetal macrosomia in women with gestational diabetes mellitus (GDM) and discuss effective methods for reducing the incidence of this disease.  Methods  A total of 1 135 single pregnancy women with GDM who were admitted to Zhengzhou First People's Hospital from January 2014 to December 2018 were retrospectively analysed. They were divided into macrosomia group (175 cases with body weight of ≥4 000 g) and non-macrosomia group (960 cases with body weight of < 4 000 g).  Results  The incidence of GDM macrosomia was 15.42%, and this disease was found to be associated with family history of diabetes in pregnant women, pre-pregnancy BMI, gain too much pregnancy weight and high fasting blood glucose (all P < 0.05). The pregnant women in the macrosomia group were with a high incidence of gestational hypertension, surgical delivery and adverse pregnancy outcomes of premature delivery, neonatal hypoglycemia, fetal distress and postpartum haemorrhage, which were significantly higher than those in the non-GDM macrosomia group (all P < 0.05). The risk factors of neonatal hypoglycemia in the GDM macrosomia group was 1.599 times (95% CI: 0.938-2.726), 1.756 times (95% CI: 1.132-2.723) and 2.489 times (95% CI: 1.385-4.471) that in the non-macrosomia group.  Conclusion  GDM macrosomia can increase adverse pregnancy outcomes, such as surgery, preterm delivery, fetal distress, pregnancy hypertension and massive haemorrhage during labour. Pregnant women must be screened for oral glucose tolerance test (OGTT), their traditional diet and lifestyle must be changed, their weight gain and increase in blood sugar levels during pregnancy must be strictly limited and nursing intervention should be implemented during the entire process of intrapartum and puerperium to control the risk factors of GDM. These steps can effectively reduce the incidence of GDM macrosomia and reduce the risk of adverse pregnancy outcomes.

     

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