2021 Vol. 19, No. 6

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Expert Forum
International experience and practice of integrated primary care in China
ZHANG Ya-lin, LIAO Xiao-yang, ZHAO Qian, LEI Yi, LI Zhi-chao, TANG Yi-jun, LI Ni
2021, 19(6): 887-891. doi: 10.16766/j.cnki.issn.1674-4152.001942
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With the acceleration of the global aging process and the outbreak of chronic diseases, the demand for health services is increasing, and the "fragmentation" of health services is becoming increasingly prominent. Therefore, integrated health service has become a worldwide trend of health system refo...
2021, 19(6): 892-893.
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Mechanism of Portulaca oleracea L. in the treatment of non-alcoholic fatty liver disease based on data analysis
WANG Xin, WU Qiao-min, TANG Yu-xiao, ZHANG Mei-fang, CHEN Jie-wen
2021, 19(6): 950-953. doi: 10.16766/j.cnki.issn.1674-4152.001958
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259 5
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Objective To explore the molecular mechanism of Portulaca oleracea L. in the treatment of non-alcoholic fatty liver (NAFLD). Methods With the use of the TCMSP and Drug Bank and Uniprot database, the effective activity of Portulaca oleracea L. was screened out ingredients and their potential targets....
Initiation of antiretroviral treatment among HIV-infected pregnant women and associated factors
HUANG Zhao-hui, ZHANG Yue, GUOLIU Run-nan, HU Lin-feng, FENG Fang, ZHAI Qian, FANG Liang, LIU Kai
2021, 19(6): 954-958. doi: 10.16766/j.cnki.issn.1674-4152.001959
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277 4
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Objective The proportion of antiretroviral treatment among HIV-infected pregnant women is an important evaluation index for the program of china's women development. However, the anticipated goals of such programs are difficult to achieve in Anhui province. This paper aimed to analyse the proportion...
Analysis of influencing factors and pregnancy outcomes of macrosomia among pregnant women with diabetes in a hospital in Zhengzhou City from 2014 to 2018
CHEN Yu-rong, DUAN Xiao-kai, LIU Chun-fan, YANG Xiao, JIANG Yan-li, ZHANG Zhen-xiang, DU Shao-fei
2021, 19(6): 959-963. doi: 10.16766/j.cnki.issn.1674-4152.001960
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Objective To analyse the influencing factors and pregnancy outcomes of fetal macrosomia in women with gestational diabetes mellitus (GDM) and discuss effective methods for reducing the incidence of this disease. Methods A total of 1 135 single pregnancy women with GDM who were admitted to Zhengzhou ...
Effect of pelvic floor rehabilitation on pelvic floor function after total laparoscopic hysterectomy
CUI Xia, WANG Wen-yan, LING Lin, ZHAN Lei, WEI Bing
2021, 19(6): 964-968. doi: 10.16766/j.cnki.issn.1674-4152.001961
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375 3
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Objective To investigate the effects of pelvic floor muscle exercise combined with biofeedback electrical stimulation on pelvic floor muscle function and quality of life after laparoscopic total hysterectomy. Methods A total of 60 patients who underwent laparoscopic total hysterectomy in the Second ...
Risk factors of shoulder dystocia during maternal delivery and the evaluation of the intervention effect of posterior shoulder rotation
LU Ying, YOU Ai-jun, WU Jia-han
2021, 19(6): 969-971. doi: 10.16766/j.cnki.issn.1674-4152.001962
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241 3
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Objective To explore the risk factors of shoulder dystocia during maternal delivery and the intervention effect of posterior shoulder rotation. Methods Data of 5 812 women who underwent vaginal delivery in Ningbo Women's and Children's Hospital from January 2019 to January 2020 were collected, inclu...
Comparison of the effect of different antibiotic treatment regimens on intestinal microecology and peripheral blood T lymphocyte subsets in infants
ZHONG Sheng-fen, ZHOU Wen-can, NI Miao-jun, ZHU Yu-qing, WEN Chao, JIN Ji, YANG Yu
2021, 19(6): 972-974. doi: 10.16766/j.cnki.issn.1674-4152.001963
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260 3
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Objective To investigate the effect of different antibiotic treatment regimens on intestinal microecology and peripheral blood T lymphocyte subsets in infants. Methods A total of 72 infants treated with antibiotics in the Maternal and Child Health Hospital of Fuyang District, Hangzhou from January 2...
Analysis of community health service utilisation for young and middle-aged building population in Beiwaitan Street, Shanghai
HUANG Jiao-ling, CUI Ya-qi, HAO Yu, LIU Tie-xin, TAN Xin-chen, YANG Yong-hua, MA Xiao-jun, LIN Jie, YU Wen-ya, WANG Zhao-xin
2021, 19(6): 975-978. doi: 10.16766/j.cnki.issn.1674-4152.001964
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Objective To explore the current status of community health service utilisation among young and middle-aged population and analyse the main factors affecting visits to community health service center (CHSC). Methods From August to September in 2019, A questionnaire survey was conducted on Beiwaitan ...
Association of blood cell parameters with non-alcoholic fatty liver disease in the elderly with hypertension
WANG Cheng-cheng, LIU Huai-lei, GONG Wei-hong
2021, 19(6): 979-981, 1007. doi: 10.16766/j.cnki.issn.1674-4152.001965
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Objective This study aimed to investigate the relationship between blood cell parameters and non-alcoholic fatty liver disease (NAFLD) in the elderly with hypertension and provide scientific evidence for the prevention and control of NAFLD in elderly hypertensive patients. Methods The cluster sampli...
The mediating effect of psychological capital on perceived social support and intent to stay in midwives
SHI Wei-hui, ZHU Xiao-ping, YUAN Xiao-yu, WANG Ling, QIU Chang-cui, SHI Yan
2021, 19(6): 982-985. doi: 10.16766/j.cnki.issn.1674-4152.001966
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Objective To explore the mediating effect of psychological capital on the perceived social support and the intent to stay in midwife. Methods Using the method of convenience sampling, midwives from secondary and tertiary hospitals in Shanghai were selected from January to march in 2020. A total of 2...
Effect of home nutrition support on nutritional status and psychological pain of patients with gastric cancer after surgery
ZHU Jin-cheng, HUANG Hong, ZHANG Hao-ran, ZHAO Cun-xi
2021, 19(6): 986-989. doi: 10.16766/j.cnki.issn.1674-4152.001967
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Objective To investigate the status of malnutrition and psychological distress in patients with gastric cancer after operation and observe the effect of family nutritional support on postoperative nutritional status and psychological distress of patients with gastric cancer. Methods A total of 166 p...
Expression and clinical diagnostic of serum miR-92a-1 in patients with colorectal cancer
WU Xiao-yu, CUI Fa-cai, HU Min, ZHU Ya, ZHENG Pei-ming
2021, 19(6): 990-993. doi: 10.16766/j.cnki.issn.1674-4152.001968
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Objective This study aimed to investigate the expression of serum miR-92a-1 and its clinical diagnostic value in patients with colorectal cancer (CRC). Methods The serum samples of 131 patients with CRC and 50 patients with colorectal adenomas (CRA), who were hospitalised from May 2018 to December 2...
Study of multimode MRI in the diagnosis of early-stage patellar cartilage injury
WANG Dong-yu, LUO Xiao-ping, LIU Xu-ming, XIANG Jian-yu, HUANG Xu-hao
2021, 19(6): 994-997. doi: 10.16766/j.cnki.issn.1674-4152.001969
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256 3
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Objective To investigate the diagnostic value of diffusion tensor imaging (DTI) and T2*mapping in the evaluation of early-stage patellar cartilage injury. Methods Thirty-two cases with patellar cartilage injury and 31 cases with normal patellar cartilage were examined through arthroscopy, and their ...
Observe on the clinical effect of MRI in vascular dementia after ischemic stroke
WANG Guo-yu, SHI Yi-ming, WANG Zeng-xian, CHEN Feng
2021, 19(6): 998-1000, 1025. doi: 10.16766/j.cnki.issn.1674-4152.001970
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Objective To observe the characteristics of brain magnetic resonance imaging (MRI) in patients with vascular dementia after ischemic stroke and evaluate the value of MRI in the early diagnosis and monitoring of the disease. Methods A total of 200 patients with ischemic stroke who were treated in Tai...
Mechanisms of Osteoarthritis Pain
QIN Xi-ru, ZHANG Li-zhi
2021, 19(6): 1001-1007. doi: 10.16766/j.cnki.issn.1674-4152.001971
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Osteoarthritis (OA) is the most common joint disease, and its incidence is increasing by years. Currently, there is no effective cure, yet OA is one of the most common causes of functional disability in the elderly. The insufficient knowledge of knee OA and subsequent delayed prevention and treatmen...
Research progress of triglyceride glucose index in coronary atherosclerotic heart disease
WANG Shuo-shan, WU Jing-guo, JING Xiao-li, ZHANG Yong-wei, TANG Hao
2021, 19(6): 1008-1012. doi: 10.16766/j.cnki.issn.1674-4152.001972
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Coronary heart disease (CHD) is still one of the main diseases threatening human health. With the development of economy, and the improvement of our living standards, the incidence of insulin resistance is increasing. Insulin resistance is closely related to the occurrence and development of CHD. Th...
Research progress of MicroRNA-429 in gynecological malignant tumors
LI Li-yang, XU Peng, WANG Bei-di, GAO Shuang, GUO Yu, KUANG Ye
2021, 19(6): 1013-1016,1034. doi: 10.16766/j.cnki.issn.1674-4152.001973
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Gynecological malignant tumors is a problem that threatens women's health, of which early diagnosis and treatment are of great significance to the prognosis. MicroRNA (miRNA) is a small non-coding RNA involved in post-transcriptional regulation of cells, which plays a key role in the normal physiolo...
Effect of Yiwei Fuzheng Decoction on Qi deficiency and blood stasis type precancerous lesion and its related mechanism
WU Xian, WANG Hai-bo, LOU Chao-sheng, ZHANG Yin, YE Le-chi
2021, 19(6): 1017-1021. doi: 10.16766/j.cnki.issn.1674-4152.001974
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Objective To investigate the effect of Yiwei Fuzheng Decoction on qi deficiency and blood stasis precancerous lesion (PLGC) and its effect on the expression of gastric mucosal histone kinase B/rapamycin target protein (AKT/mTOR) pathway. Methods There were 88 patients with qi-deficiency and blood st...
Application value of comprehensive myopenia training intervention in stroke rehabilitation training and its preventive effect on myopenia
HONG Jing, RAO Su-yu, ZHOU Hai-tao, XUE Yang-jing
2021, 19(6): 1022-1025. doi: 10.16766/j.cnki.issn.1674-4152.001975
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500 4
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Objective To study the application value of rehabilitation training in stroke and its preventive effect on myopenia. Methods A total of 100 inpatients who suffered from stroke and admitted from July 2020 to December 2020 were divided into the control and observation groups of 50 cases each. The cont...
Application of DOPS as formative evaluation in basic health services in graduation practice
HE Yi-ni, QI Dian-jun, CHEN Xin-yue, ZHU Liang-liang, QI Hui-meng, WANG Shuang, YU Xiao-song
2021, 19(6): 1026-1028, 1052. doi: 10.16766/j.cnki.issn.1674-4152.001976
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Objective To discuss the effect of direct observation of procedural skills (DOPS) as formative evaluation in basic health services in graduation practice. Methods Total 62 fifth-year undergraduates from The Clinical Medicine Major University of China Medical University were selected as study subject...
The efficacy of high-flow nasal cannula oxygen therapy for patients after extubation: an overview of systematic reviews
LIU Qin, XIE Xiang-mei, LUO Jia-jia, JIAO Fan, HU Xiao-ying
2021, 19(6): 1029-1034. doi: 10.16766/j.cnki.issn.1674-4152.001977
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Objective The aim of this paper was to evaluate the methodological quality and of evidence level for the best evidence, to compare the efficacy and safety of high-flow oxygen therapy with other therapy methods in patients after extubation, and provide reference for the future research priorities of ...
Analysis of related metabolic indexes of non-alcoholic fatty liver disease in the elderly popluation of public institutions in Nanjing
SUN Hui-wen, ZHAN Yi-yang, CHEN Min-min, JIANG Min, WANG Chun, WANG Qin, ZHENG Wen
2021, 19(6): 1035-1038. doi: 10.16766/j.cnki.issn.1674-4152.001978
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Objective To investigate the prevalence of non-alcoholic fatty liver disease (NAFLD) in the elderly physical examination population in institutions in Nanjing in 2016 and to analyse the correlation between NAFLD and metabolic indicators, such as triglyceride glucose product index (TyG index). Method...
Awareness of adult calcium supplement and its influencing factors among general practitioner in Zhejiang Province
YANG Chen-bin, LI Yan-mei, LI Zhang-ping, NI Yun-chao, WU Hui-lei
2021, 19(6): 1039-1042. doi: 10.16766/j.cnki.issn.1674-4152.001979
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Objective To investigate and analyze the cognition and influencing factors of general practitioners on adult calcium supplementation in Zhejiang province, and to provide the decision-making basis for targeted education. Methods A questionnaire was designed, including the basic information, the knowl...
Epidemiological investigation and clinical symptom analysis of influenza among children in a hospital of Bengbu City from 2018 to 2019
WANG Le-le, HAN Xu, ZHANG Qi, CHEN Xin
2021, 19(6): 1043-1045,1064. doi: 10.16766/j.cnki.issn.1674-4152.001980
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Objective To analyse the epidemiological characteristics and clinical symptoms of influenza among children in a hospital of Bengbu City from 2018 to 2019 so as to provide basis for the prevention and treatment of influenza. Methods A total of 528 children diagnosed with influenza and hospitalised in...
Nursing care of elderly patients with maxillary sinus lifting and simultaneous implant implantation
ZHU Li, YU De-dong, XU Yun-xia
2021, 19(6): 1046-1048. doi: 10.16766/j.cnki.issn.1674-4152.001981
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278 2
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Objective To explore the nursing effect of targeted nursing on elderly patients with maxillary sinus simultaneous implantation. Methods A total of 42 elderly patients with maxillary posterior tooth loss treated with implant prosthesis admitted to the Second Outpatient Department of the Ninth People'...
Application of cluster nursing management to the treatment of orthopaedic trauma with infection through vacuum sealing drainage
CHEN Zhi-hui, ZENG Zhong-you, QIAN Jin-feng
2021, 19(6): 1049-1052. doi: 10.16766/j.cnki.issn.1674-4152.001982
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Objective To investigate the application of cluster nursing management to the treatment of orthopaedic trauma patients with infection through vacuum sealing drainage and provide novel methods for clinical nursing. Methods A total of 150 patients with trauma infection who were hospitalized in the Dep...
Application of risk nursing combined with continuous quality improvement in the safety management of intravenous drug use in daytime chemotherapy
BO Li-mei, WEI Yun-hai, BIAN Yuan-yuan
2021, 19(6): 1053-1056. doi: 10.16766/j.cnki.issn.1674-4152.001983
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319 4
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Objective To improve the safety management of drug use in patients undergoing daytime chemotherapy, this study used risk nursing combined with continuous quality improvement on the basis of routine nursing to evaluate the nursing value and significance of the strategy. Methods A total of 140 patient...
Effect of evidence-based clinical nursing pathway on emergency thrombolytic therapy in patients with acute cerebral infarction
WANG Fu-qin, ZHU Wei-li, YUAN Ming, MA Li-na, XU Min
2021, 19(6): 1057-1060. doi: 10.16766/j.cnki.issn.1674-4152.001984
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Objective Acute cerebral infarction (ACI) has high disability and mortality rates. To improve the nursing quality of patients with ACI, this study used an evidence-based clinical nursing pathway and analysed its effect. Methods A total of 126 patients with ACI who received emergency Emergency thromb...
2021, 19(6): 1061-1064. doi: 10.16766/j.cnki.issn.1674-4152.001985
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2021, 19(6): 1065-1068. doi: 10.16766/j.cnki.issn.1674-4152.001986
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General Practice Research
Clinical characteristics and risk factors of heart failure patients after hematopoietic stem cell transplantation treatment
XUE Lu-xin, LI Xiao-yang, WANG Jing
2021, 19(6): 894-897. doi: 10.16766/j.cnki.issn.1674-4152.001943
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217 6
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Objective To explore the clinical characteristics and risk factors of patient with heart failure after haematopoietic stem cell transplantation(HSCT), improve methods for the early recognition and intervention for patients with heart failure after haematopoietic stem cell transplantation and improve...
Influencing factors of hemorrhagic transformation in non-thrombolytic patients after acute large area cerebral infarction
LIU Li-jun, LIU Xue-yun, WU Xiao-san, QIU Ju, WU Tong, HAN Yong-sheng, WANG Xun
2021, 19(6): 898-900,907. doi: 10.16766/j.cnki.issn.1674-4152.001944
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187 6
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Objective This study was aimed to explore the influencing factors of hemorrhagic transformation (HT) in non-thrombolytic patients with acute massive cerebral infarction by analyzing the differences in factors between the massive cerebral infarction hemorrhage transformation group and the non-hemorrh...
Safety and effectiveness of tranexamic acid in patients combined with high risk comorbidities for postoperative venous thromboembolism during total knee arthroplasty
ZOU Chun-yu, YUE Chen, YANG Lan-bo, MI Yu-fei, WANG Zhan-chao
2021, 19(6): 901-903. doi: 10.16766/j.cnki.issn.1674-4152.001945
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288 5
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Objective To assess the safety and efficacy of tranexamic acid (TXA) in patients with high risk comorbidities for venous thromboembolic events (VTE) during total knee arthroplasty (TKA). Methods We chose eight risk factors for postoperative VTE during TKA. Patients in Luoyang Orthopedic Hospital of ...
Effects of epidural labour analgesia on delivery process, delivery mode and postpartum depression
SONG Yu-rong, ZHAN Lei, SUN Li
2021, 19(6): 904-907. doi: 10.16766/j.cnki.issn.1674-4152.001946
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232 3
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Objective To analyse the effects of epidural labor analgesia (LA) on the process and mode of delivery and the risk of postpartum depression (PPD) by comparing labour-related indicators and postpartum depressive symptoms between LA-treated and non-analgesia groups. Methods In the prospective cohort s...
Correlation between stress hyperglycaemia ratio and early cognitive dysfunction in patients with anterior circulation perforator arteriosclerotic cerebral infarction
WANG Jing-yue, SUN Bo, PENG Yan-bo, CHAI Hai-xia, FAN Hai-yan, BIAN Zhe
2021, 19(6): 908-912. doi: 10.16766/j.cnki.issn.1674-4152.001947
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217 6
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Objective To discuss the effects of high blood sugar stress ratio on early cognitive dysfunction of patients with Anterior circulation perforator arteriosclerotic cerebral infarction. Methods From December 2014 to December 2019, patients with anterior circulation perforator arteriosclerotic cerebral...
Multiple methods to establish rat endometrial deep injury model
ZHANG Yi, HU Xiu-juan, DAI Zhi-jun, LIU Chao, HONG Ming-yun
2021, 19(6): 913-916,1012. doi: 10.16766/j.cnki.issn.1674-4152.001948
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Objective To establish an animal model of rat endometrial deep injury, and to provide a basis for subsequent treatment of endometrial injury with endometrial stem cells combined with biological scaffolds. Methods Fifteen healthy female rats with normal oestrous cycle were randomly divided into the f...
Sestrin 2 extenuates neuronal ferroptosis induced by sevoflurane through the Nrf2/xCT pathway
LI Fu-jun, JIANG Tao, GUO Li-jia, WANG Shun
2021, 19(6): 917-920,. doi: 10.16766/j.cnki.issn.1674-4152.001949
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399 5
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Objective To explore the role of Sestrin 2 (SESN2) in neuronal ferroptosis induced by sevoflurane (SEV) and its possible mechanism. Methods Mouse hippocampal neuron cells HT22 were treated with 0%, 1%, 2% or 4% sevoflurane and iron death inhibitor Ferrostatin-1 (FER-1) for 6 h. SESN2 overexpression ...
Expressions of TLR9 and STAT3 and their correlation with IL-10 in patients with ulcerative colitis
ZHANG Wen-ting, GU Lin, KE Xi-quan, WANG Qi-zhi, WANG Qiang-wu, WANG Jian-chao, LI Da-peng
2021, 19(6): 921-924. doi: 10.16766/j.cnki.issn.1674-4152.001950
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318 5
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Objective The expression levels of toll-like receptor 9 (TLR9), signal transduction and transcriptional activator factor 3 (STAT3) and interleukin-10 (IL-10) in peripheral blood and intestinal mucosal tissues of patients with ulcerative colitis (UC) were detected to explore their roles in the pathog...
Application effect of Angong Niuhuang Pills in patients with cardiac arrest after cardiopulmonary resuscitation
LYU Xin, ZHANG Ying, TANG Wen-xue
2021, 19(6): 925-928,1038. doi: 10.16766/j.cnki.issn.1674-4152.001951
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337 3
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Objective To observe the application value of Angong Niuhuang Pills in patients with emergency cardiac arrest (CA) after cardiopulmonary resuscitation (CPR). Methods Total 90 patients with CA and return of spontaneous circulation (CA-ROSC) who were admitted to the General Intensive Care Unit (GICU) ...
Application of extraperitoneal oblique tunnel sigmoidostomy in laparoscopic Miles operation
JIA Wei, LIU Mu-lin, ZHU Bing, LUO Jie
2021, 19(6): 929-931,1060. doi: 10.16766/j.cnki.issn.1674-4152.001952
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Objective To investigate the clinical effect of extraperitoneal oblique tunnel sigmoidostomy in laparoscopic abdominoperineal radical resection of rectal cancer., Methods The clinical data of 104 patients with low rectal cancer who underwent laparoscopic abdominoperineal resection (Miles) from Janua...
Protective effects of Panax notoginseng saponins on P13K/Akt/mTOR signalling pathway and neuronal apoptosis in hippocampus of rats with traumatic brain injury
LIN Chen, CHEN Chuang
2021, 19(6): 932-935. doi: 10.16766/j.cnki.issn.1674-4152.001953
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320 2
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Objective To investigate the protective effects of Panax notoginseng saponins on the P13K/Akt/mTOR signalling pathway and neuronal apoptosis in the hippocampus of rats with traumatic brain injury (TBI). Methods Forty-five SPF SD rats were randomly divided into normal, model and Panax notoginseng sap...
General Clinical Research
Application of 3D-CTA in peroneal artery perforator flap for repairing postoperative soft tissue defect of tongue carcinoma
XU Cao, WANG Shu-qin, HU Kai, SONG Pei-jun, WU Zhi-gang, CHEN Mo, SUN Yue, LI Jian-cheng
2021, 19(6): 936-939,978. doi: 10.16766/j.cnki.issn.1674-4152.001954
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Objective With the development of imaging technology, the visual perforator flap is becoming more and more mature. By analyzing the clinical application effect of 3D-CTA in the peroneal perforator flap to repair the soft tissue defect after tongue cancer surgery, it provides the basis for the design...
Retrospective analysis of ultrasound-guided and blind central vein catheterisation
HUANG Lei, DI Jia-mei, ZOU Bao, DUAN Bing-hui, LIU Zhi, ZHANG Chao-xue
2021, 19(6): 940-943. doi: 10.16766/j.cnki.issn.1674-4152.001955
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264 3
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Objective Retrospective analysis of the effect of ultrasound guidance and traditional blind puncture in different regions of central venous catheterisation. Methods A total of 117 patients with renal failure who were hospitalised in the Department of Nephrology of the First Affiliated Hospital of An...
Effect of pressure controlled ventilation on postoperative delirium in elderly patients with spinal tuberculosis
WANG Shun, WAN Hai-fang, NI Yan-hua
2021, 19(6): 944-946,968. doi: 10.16766/j.cnki.issn.1674-4152.001956
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251 2
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Objective To explore the effect of pressure-controlled ventilation (PCV) mode on postoperative delirium (POD) in elderly patients with spinal tuberculosis. Methods A total of 72 elderly patients suffering from spinal tuberculosis and admitted to a hospital from September 2018 to September 2019 were ...
Correlation of serum inflammatory factors and pulmonary function with the severity of OSAHS
YAN Xian-ting, HUANG Qing-dong, TANG Ting-yu, WANG Yan-hong, LU Xiao-ling
2021, 19(6): 947-949. doi: 10.16766/j.cnki.issn.1674-4152.001957
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Objective To investigate the correlation between inflammatory factors and lung function and the severity of obstructive sleep apnea-hypopnea syndrome (OSAHS) to provide reference for clinical treatment. Methods The 179 OSAHS patients from Zhejiang Hospital from March 2018 to March 2020 were selected...

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