Abstract: Objective To observe press the effect of needle-embedding therapy combined with rehabilitation training on the knee joint pain and dysfunction in patients with knee osteoarthritis. Methods By using random numbers table,40 patients with knee osteoarthritis in our hospital between January,2016 and June,2016 were randomly divided into observation group and the control group with 20 cases in each group.The observation group received needle-embedding therapy combined with rehabilitation training,while the control group only received conventional rehabilitation training.The function of knee joint pain,stiffness and degrees of knee extension were evaluated by using western Ontario and McMaster osteoarthritis index(WOMAC) in both groups before the treatment,immediately after the first therapy.0ne month after the treatment,and three months after the treatment during the follow-up.The visual analogue scale(VAS) was conducted for the score in all patients.The range of motion(ROM) by common protractor and the knee joint function assessment were performed before the treatment and one month after the therapy to make curative effect evaluation. Results At the end of the first treatment,WOMAC scores in the observation group was improved significantly,the difference was statistically significant(P<0.05),but not in the control group(P>0.05);One month after the therapy,WOMAC score in both groups was improved obviously,so for each item,the difference was statistical significance(P<0.05);After one month treatment,the difference in WOMAC score between two groups was statistical significant(P<0.05).The total effective rate of the observation group was 95% and of the control group was 70%,the difference was statistically significant(P<0.05);After 3 months follow-up,the WOMAC score of the two groups increased as compared with the data at 1 month after treatment,and significantly higher than that before the treatment(P<0.05),the WOMAC score between the two groups had statistically significant difference(P<0.05). Conclusion Needle-embedding analgesic therapy combined with joint rehabilitation for the patients with knee osteoarthritis can effectively improve the knee arthritis pain and dysfunction.