Abstract: Objective To evaluate the influence of different dental implant simulation software on the accuracy of surgical template. Methods Sixteen healthy people were chosen for the analysis.All the patients were scanned with cone beam computerized tomography (CBCT) and the data were imported into the different dental implant simulation software,53 implants were planned and the stereolithographic (SLA) surgical templates were made with the technology of SLA.The surgical templates designed by Simplant were group A,designed by 6D implant were group B.A CBCT scan of the surgical template fitted on plaster model was performed,and the images were matched with the virtual implant plan images,the actual implant position was acquired from the position of surgical template.The deviation between the actual and planned implant position was analyzed. Results Group A:the deviation at the hex was (0.582±0.216) mm,horizontal deviation was (0.226±0.132) mm,vertical deviation was (0.522±0.213) mm;apex deviation was (0.643±0.256) mm,horizontal deviation was (0.332±0.222) mm,vertical deviation was (0.524±0.214) mm;contact radio was (88.7±4.6)%.Group B:the deviation at the hex was (0.456±0.222) mm,horizontal deviation was (0.193±0.123) mm,vertical deviation was (0.388±0.238) mm;apex deviation was (0.515±0.233) mm,horizontal deviation was (0.277±0.19) mm,vertical deviation was (0.39±0.236) mm;contact radio was (91.1±4.0)%. Conclusion The influence of different implant simulation software on the accuracy has statistical significance.