Abstract: Objective To investigate the current situation and influential factors of clinical nurses' perception of adverse events,and discuss the corresponding measures for improving the risk awareness of nurses. Methods The on-site survey was conducted among 917 clinical nurses from ten hospitals in Taian city between April,2015 and August,2015 using a self-designed demographic questionnaire and Clinical Nurses Adverse Events Risk Perception Structure Scales to investigate the influential factors of clinical nurses' perception of adverse events.The data were analyzed with SPSS 19.0 and AMOS 17.0. Results A scale of three factors and 20 items was identified by using item analysis and exploratory factor analysis.Exploratory and confirmatory factor analysis revealed that there were three dimensions of adverse events risk perception:patient care risk,system process risk and nurse operation risk.The score of clinical nurses adverse events risk perception was 16.48±3.79.The score of each dimension in descending order were:nurse operation risk,system process risk and patient care risk.Work experience,departments and hospital level were the significant influencing factors of clinical nurses' risk perception of adverse events. Conclusion The level of clinical nurses' perception of adverse events need to be improved.The nurse managers should pay more attentions to improve nurse risk awareness and reporting adverse event in order to promote the management of the safety of patients and reduce occurrence of adverse event.