中药封包疗法对甲状腺癌患者术后颈部疼痛的临床疗效观察

丁云; 张浩; 马小鹏; 闫春玲; 陈婷婷; 赵红

doi:10.16766/j.cnki.issn.1674-4152.004101

中药封包疗法对甲状腺癌患者术后颈部疼痛的临床疗效观察

doi: 10.16766/j.cnki.issn.1674-4152.004101

丁云¹,
张浩²,
马小鹏³,
闫春玲¹,
陈婷婷¹,
赵红^4, ,

1.
安徽中医药大学第一附属医院甲状腺乳腺外科，安徽合肥 230031
2.
安徽中医药大学第一临床医学院，安徽合肥 230012
3.
中国科学技术大学附属第一医院，安徽合肥 230001
4.
安徽中医药大学第一附属医院护理部

基金项目:

安徽省卫生健康科研项目 AHWJ2022b011

详细信息

通讯作者:
赵红，E-mail：487985728@qq.com

中图分类号: R736.1 R244
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- 文章访问数: 9
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出版历程
- 收稿日期: 2025-03-22
- 网络出版日期: 2025-10-25

Clinical observation on the efficacy of traditional Chinese medicine compression pack therapy for postoperative neck pain in thyroid cancer patients

1.
Department of Thyroid and Breast Surgery, the First Affiliated Hospital of Anhui University of Traditional Chinese Medicine, Hefei, Anhui 230031, China

摘要

摘要: 目的评估中药封包疗法治疗甲状腺癌患者术后颈部疼痛的临床疗效，分析其对术后恢复的改善作用，并观察治疗的安全性。方法采用随机数字表法将2025年1—3月于安徽中医药大学第一附属医院甲状腺乳腺外科接受甲状腺癌根治术且术后出现颈部疼痛的76例患者分为治疗组与对照组，每组38例。对照组予以常规护理，治疗组在对照组基础上加用中药封包疗法。本研究采用数字评分量表(NRS)、简明疼痛评估量表(BPI)评价2组患者手术后1 h、手术后3 d疼痛情况。采用术后恢复质量量表-15(QoR-15)评价患者手术前1 d、手术后3 d手术恢复情况，并比较2组患者手术后不良反应发生情况。结果组内比较：治疗组手术后3 d的NRS、BPI评分较手术后1 d显著降低(P＜0.05)。组间比较：治疗组手术后3 d NRS评分为[0(0, 0)]分，显著低于对照组[1(1, 1)分，Z=-6.595，P＜0.001]；治疗组手术后3 d BPI疼痛强度得分为(6.71±2.54)分，显著低于对照组[(8.89±3.56)分，F=8.862，P=0.004]；治疗组手术后3 d BPI疼痛影响得分为(15.00±5.80)分，显著低于对照组[(19.68±4.27)分, F=15.027，P＜0.001]；治疗组手术后3 d QoR-15评分为(130.42±9.36)分，显著高于对照组[(121.76±8.38)分, F=17.805，P＜0.001]。2组患者在治疗期间均未出现不良反应。结论相较于对照组，中药封包疗法可以更好地改善甲状腺癌患者术后颈部疼痛，加速患者术后恢复，且安全性良好。
- 甲状腺癌 /
- 中药封包疗法 /
- 术后颈部疼痛 /
- 临床疗效
Abstract: Objective To evaluate the clinical efficacy of traditional Chinese medicine (TCM) pack therapy in managing postoperative neck pain in thyroid cancer patients. In addition, the study will analyze its role in enhancing postoperative recovery and assess treatment safety. Methods A total of 76 patients who underwent radical surgery for thyroid cancer at the Thyroid and Breast Surgery Department of the First Affiliated Hospital of Anhui University of Chinese Medicine between January and March 2025, and developed postoperative neck pain were randomized into treatment and control groups (38 cases each) using a random number table. The control group received routine care, while the treatment group received additional TCM pack therapy. The severity of pain was measured using the numerical rating scale (NRS) and the brief pain inventory (BPI) at one hour and three days after surgery. Postoperative recovery was evaluated using the quality of recovery-15 (QoR-15) scale on the day before surgery and 3 days post-surgery. Adverse reactions were also recorded. Results A comparison was made between the groups. In the treatment group, NRS and BPI scores at 3 days postoperatively were significantly decreased in comparison with those at 1 day postoperatively (P < 0.05).Inter-group comparison: Three days after the operation, the treatment group exhibited a significantly lower NRS score [0 (0, 0)] than the control group [1 (1, 1), Z=-6.595, P < 0.001]. Furthermore, the treatment group demonstrated a lower BPI pain intensity score (6.71±2.54 vs. 8.89±3.56, F=8.862, P=0.004), indicating a lower level of interference with pain. Similarly, the mean score for the QoR-15 scale was higher (130.42±9.36 vs. 121.76±8.38, F=17.805, P < 0.001). No adverse reactions were observed in either group during treatment. Conclusion In comparison with the control group, TCM pack therapy significantly alleviated postoperative neck pain, accelerated recovery, and demonstrated favorable safety in thyroid cancer patients.
- Thyroid cancer /
- Traditional Chinese medicine pack therapy /
- Postoperative neck pain /
- Clinical efficacy

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表 1 2组甲状腺癌根治术患者一般资料比较

Table 1. Comparison of general characteristics between two groups of patients undergoing radical thyroidectomy for thyroid cancer

组别	例数	性别(例)		年龄(x ± s，岁)
组别	例数	女性	男性	年龄(x ± s，岁)
治疗组	38	28	10	43.74±11.22
对照组	38	30	8	44.61±11.88
统计量		0.291^a		0.328^b
P值		0.589		0.736
注：^a为χ²值，^b为t值。

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表 2 组甲状腺癌根治术患者术后NRS评分比较[M(P₂₅, P₇₅)，分]

Table 2. Comparison of NRS scores before and after treatment between two groups of patients undergoing radical thyroidectomy for thyroid cancer [M(P₂₅, P₇₅), points]

组别	例数	手术后1 h	手术后3 d
治疗组	38	3(3，3)	0(0，0)^a
对照组	38	3(3，3)	1(1，1)^a
Z值		-1.000	-6.595
P值		0.317	＜0.001
注：与同组手术后1 h比较，^aP＜0.05。

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表 3 2组甲状腺癌根治术患者术后BPI量表比较(x ± s，分)

Table 3. Comparison of BPI scores before and after treatment between two groups of patients undergoing radical thyroidectomy for thyroid cancer (x ± s, points)

组别	例数	BPI疼痛强度		BPI疼痛影响情况
组别	例数	手术后1 h	手术后3 d	手术后1 h	手术后3 d
治疗组	38	8.53±3.42	6.71±2.54^b	21.37±5.51	15.00±5.80^b
对照组	38	9.50±2.76	8.89±3.56	20.34±5.10	19.68±4.27
统计量		1.361^a	8.862^c	0.846^a	15.027^c
P值		0.178	0.004	0.400	＜0.001
注：^a为t值，^c为F值。与同组手术后1 h比较，^bP＜0.05。

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表 4 2组甲状腺癌根治术患者术后QoR-15问卷评分比较(x ± s，分)

Table 4. Comparison of QoR-15 scores before and after treatment between two groups of patients undergoing radical thyroidectomy for thyroid cancer (x ± s, points)

组别	例数	手术前1 d	手术后3 d
治疗组	38	139.00±6.91	130.42±9.36^b
对照组	38	138.87±8.16	121.76±8.38^b
统计量		0.075^a	17.805^c
P值		0.940	＜0.001
注：^a为t值，^c为F值。与同组手术前1 d比较，^bP＜0.05。

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