安徽滁州地区体检人群幽门螺杆菌感染现状及危险因素分析

李群; 沈君; 史万青; 林宁; 侯仕强

doi:10.16766/j.cnki.issn.1674-4152.003996

安徽滁州地区体检人群幽门螺杆菌感染现状及危险因素分析

doi: 10.16766/j.cnki.issn.1674-4152.003996

李群¹,
沈君¹,
史万青¹,
林宁²,
侯仕强^2, ,

1.
安徽医科大学附属滁州医院，滁州市第一人民医院健康体检与管理中心，安徽滁州 239000
2.
安徽医科大学附属滁州医院，滁州市第一人民医院神经外科

基金项目:

安徽省科技厅重点研究与开发计划项目 2022e07020069

详细信息

通讯作者:
侯仕强，E-mail：houshiqiang@ahmu.edu.cn

中图分类号: R446.5 R57
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- 文章访问数: 8
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- PDF下载量: 0
- 被引次数: 0
出版历程
- 收稿日期: 2024-11-30
- 网络出版日期: 2025-08-14

Prevalence and risk factors of Helicobacter pylori infection in the physical examination population in Chuzhou, Anhui Province

1.
Health Examination and Management Center, the Affiliated Chuzhou Hospital of Anhui Medical University, the First People ' s Hospital of Chuzhou, Chuzhou, Anhui 239000, China

摘要

摘要: 目的分析安徽滁州地区体检人群的幽门螺杆菌(HP)感染现况和相关危险因素，为地区HP的防治提供新的理论依据。方法选择2023年1—12月在滁州市第一人民医院行碳14呼气试验的体检人群(2 202例)作为研究对象，根据检测结果将其分为HP阳性组(806例)和HP阴性组(1 396例)。通过问卷调查等方式收集2组人群的临床参数和生活习惯等资料进行分析，包括年龄、性别、BMI、吸烟、饮酒、常住区域、教育程度、餐前洗手、便后洗手、外出就餐、点外卖、饮食规律、作息规律和运动频率等。结果体检人群的HP总感染率为36.60%(806/2 202)，其中青年、中年和老年人群感染率分别为34.85%(176/505)、36.76%(497/1 352)和38.55%(133/345)。HP阳性组的年龄为(49.39±11.42)岁，高于HP阴性组[(48.56±11.93)岁]，但差异无统计学意义(t=1.603，P=0.109)。不同性别群体的HP感染率分别为37.67%(男性)和35.65%(女性)。男性中HP阳性组的年龄高于HP阴性组的年龄，但差异无统计学意义(P>0.05)。女性中HP阳性组的年龄高于HP阴性组的年龄，但差异无统计学意义(P>0.05)。单因素分析显示，餐前洗手(χ²=4.592，P=0.032)、外出就餐(χ²=7.949，P=0.005)、点外卖(χ²=6.826，P=0.009)、饮食规律(χ²=5.774，P=0.016)均为影响HP感染的因素，但多因素分析显示外出就餐(P=0.043)是HP感染的独立危险因素。结论安徽滁州地区体检人群HP感染率为36.60%，外出就餐是HP感染的独立危险因素，针对性采取防护措施可有效降低HP感染率。
- 碳14呼气试验 /
- 体检 /
- 幽门螺杆菌 /
- 感染 /
- 危险因素
Abstract: Objective To analyze the prevalence and related risk factors of Helicobacter pylori (HP) infection in the physical examination population in Chuzhou, Anhui Province, and to provide a theoretical basis for the prevention and management of HP in the region. Methods The physical examination population (2 202 cases) who underwent carbon 14 breath test in the First People ' s Hospital of Chuzhou City from January to December 2023 was selected as the research object. According to the test results, they were divided into the HP-positive group (806 cases) and the HP-negative group (1 396 cases). Clinical parameters and living habits of the two groups were collected and analyzed by questionnaires, including age, sex, BMI, smoking, and drinking. Results The total infection rate of HP in the physical examination population was 36.60% (806/2 202). Infection rates of young people, middle-aged people, and elderly people were 34.85% (176/505), 36.76% (497/1 352), and 38.55% (133/345), respectively. The mean age of the HP positive group was (49.39±11.42) years, slightly higher than that of the HP-negative group [(48.56±11.93) years], but the difference was not statistically significant (t=1.603, P=0.109). The infection rates of HP by sex were 37.67% in males and 35.65% in females, respectively. The mean age of HP-positive males was higher than that of HP-negative males, but the difference was not statistically significant (P>0.05). The mean age of HP-positive women was higher than that of HP-negative women, but the difference was not statistically significant (P>0.05). Univariate analysis showed that several living habits significantly associated with HP infection, including not hand washing before meals (χ²=4.592, P=0.032), dining out (χ²=7.949, P=0.005), ordering take-out (χ²= 6.826, P=0.009), and eating irregularly (χ²=5.774, P=0.016). However, multivariate analysis showed that dining out (P=0.043) was an independent risk factor for HP infection. Conclusion The HP infection rate among physical examination population in Chuzhou, Anhui Province is 36.60%. Dining out is an independent risk factor for HP infection. Implementing targeted preventive measures can effectively reduce the HP infection rate.
- Carbon 14 breath test /
- Physical examination /
- Helicobacter pylori /
- Infection /
- Risk factor

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表 1 HP感染影响因素的单因素分析(例)

Table 1. Univariate analysis of HP infection(cases)

HP结果	例数	性别					年龄(岁)			BMI				吸烟			饮酒			常住区域
HP结果	例数	男性		女性			18~39	40~59	60~79	＜24	24~28	＞28		是	否		是	否		城区	农村
阳性	806	391		415			176	497	133	339	386	81		297	509		405	401		549	257
阴性	1 396	647		749			329	855	212	523	704	169		464	932		659	737		917	479
χ²值		0.961					1.246			5.325				2.946			1.893			1.352
P值		0.327					0.536			0.070				0.086			0.169			0.245

HP结果	例数	教育程度			餐前洗手			便后洗手		外出就餐			点外卖			饮食规律			作息规律		运动频率
HP结果	例数	高中及以下	高中以上		偶尔	经常		偶尔	经常	偶尔	经常		偶尔	经常		是	否		是	否	偶尔	经常
阳性	806	561	245		436	370		204	602	193	613		604	202		629	177		615	191	643	163
阴性	1 396	919	477		689	707		311	1 085	412	984		1 113	283		1 148	248		1 014	382	1 075	321
χ²值		3.299			4.592			2.622		7.949			6.826			5.774			3.569		2.288
P值		0.069			0.032			0.105		0.005			0.009			0.016			0.059		0.130

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表 2 HP感染影响因素的logistic多因素分析

Table 2. Logistic multivariate analysis of HP infection

变量	B	SE	Waldχ²	P值	OR(95% CI)
饭前洗手	0.164	0.089	3.373	0.066	1.179(0.989~1.404)
外出就餐	0.211	0.104	4.078	0.043	1.235(1.006~1.515)
点外卖	0.174	0.112	2.415	0.120	1.190(0.955~1.483)
饮食规律	0.181	0.116	2.439	0.118	1.199(0.955~1.505)

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