针刺联合足三里穴位注射治疗持续性呃逆的疗效观察

张茹梦; 吴鸣; 许鹏; 陈育华

doi:10.16766/j.cnki.issn.1674-4152.003520

针刺联合足三里穴位注射治疗持续性呃逆的疗效观察

doi: 10.16766/j.cnki.issn.1674-4152.003520

中国科学技术大学附属第一医院(安徽省立医院)康复医学科，安徽合肥 230001

基金项目:

安徽省科技厅重点研究与开发计划项目 2022e07020021

中国科学技术大学附属第一医院2022年医学人工智能联合基金项目 MAI2022C006

详细信息

通讯作者:
吴鸣，E-mail: wumigkf@ustc.edu.cn

中图分类号: R442.1 R245.3
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- 文章访问数: 180
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- PDF下载量: 4
- 被引次数: 0
出版历程
- 收稿日期: 2023-10-19
- 网络出版日期: 2024-07-20

Observation on the curative effect of acupuncture combined with Zusanli acupoint injection in the treatment of persistent hiccups

Department of the Rehabilitation Medicine, the First Affiliated Hospital of the University of Science and Technology of China, Hefei, Anhui 230001, China

摘要

摘要: 目的探讨针刺联合足三里穴位注射甲氧氯普胺治疗持续性呃逆的有效性和安全性，比较此方法对于中枢性以及外周性持续性呃逆治疗效果的差异。方法选取2018年7月—2022年8月中国科学技术大学附属第一医院(安徽省立医院)住院患者，共入选持续性呃逆患者48例，其中中枢治疗组36例，外周治疗组12例。2组分别予以针刺攒竹、膻中、中脘、膈俞、内关、足三里等穴，留针30 min。取针后在右侧足三里(ST36)注射1 mL盐酸甲氧氯普胺，4~6 h后同剂量注射左侧足三里，共治疗3次。2组在每次治疗后以及疗程结束后分别使用呃逆评估工具(HAI)评估呃逆的严重程度；并在疗程结束后比较2组总有效率。结果治疗后，2组同组内治疗前与第1、2、3次治疗后HAI评分，第1次治疗后与第2、3次治疗后HAI评分，第2次治疗后与第3次治疗后HAI评分差异均有统计学意义(P<0.05)。且外周治疗组在第1次、第2次、第3次治疗后HAI评分均明显低于中枢治疗组[(4.25±2.60)分 vs. (6.69±2.07)分，(1.96±1.75)分vs. (3.64±3.08)分, (0.45±0.36)分 vs. (2.18±2.06)分, 均P<0.05]。2组疗程结束后总有效率比较，外周治疗组明显高于中枢治疗组[91.67%(11/12) vs. 52.78%(19/36)，χ²=4.267，P=0.039]。结论针刺联合足三里穴位注射的方法对于中枢原因或外周原因引起的持续性呃逆均有效，且对于外周原因引起的呃逆治疗效果更佳。
- 持续性呃逆 /
- 穴位注射 /
- 针刺 /
- 呃逆评估工具
Abstract: Objective To explore the efficacy and safety of acupuncture combined with Zusanli acupoint injection of metoclopramide in the treatment of persistent hiccups, and to compare the differences in the therapeutic effects of this method on central and peripheral persistent hiccups. Methods A total of 48 patients with persistent hiccups were selected from the First Affiliated Hospital of University of Science and Technology of China (Anhui Provincial Hospital) from July 2018 to August 2022, including 36 patients in the central treatment group and 12 patients in the peripheral treatment group. The two groups were treated with acupuncture at Cuanzhu, Danzhong, Zhongwan, Geshu, Neiguan, Zusanli and other points, and the needles were retained for 30 min. After taking the needle, 1ml metoclopramide hydrochloride was injected into the right Zusanli (ST36), and the same dose was injected into the left Zusanli 4-6 hours later, for a total of 3 treatments. Hiccups assessment instrument (HAI) was used to assess the severity of hiccups in the two groups after each treatment and after the end of the treatment. The total effective rate of the two groups was compared after treatment. The total effective rate of the two groups was compared after treatment. Results After treatment, there were statistically significant differences in HAI scores between before treatment and after the first, second and third treatment, between after the first treatment and after the second and third treatment, and between after the second and third treatment in two groups (all P<0.05). After the first, second and third treatment, the HAI scores of the peripheral treatment group were significantly lower than that of the central treatment group (4.25±2.60 vs. 6.69±2.07, 1.96±1.75 vs. 3.64±3.08, 0.45±0.36 vs. 2.18±2.06, P<0.05). The total effective rate of the peripheral treatment group was significantly higher than that of the central treatment group (91.67% vs. 52.78%, χ²=4.267, P=0.039). Conclusion The method of acupuncture combined with Zusanli acupoint injection is effective for persistent hiccups caused by both central and peripheral causes, and the therapeutic effect is better for peripheral causes.
- Persistent hiccup /
- Point injection therapy /
- Acupuncture /
- Hiccup assessment instrument

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表 1 2组呃逆患者年龄及总有效率比较

Table 1. Comparison of age and overall efficacy between two groups of patients with hiccups

组别	例数	年龄(x±s，岁)	总有效[例(%)]
中枢治疗组	36	56.67±11.78	19(52.78)
外周治疗组	12	63.50±15.08	11(91.67)
统计量		1.621^a	4.267^b
P值		0.112	0.039
注：^a为t值，^b为χ²值。

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表 2 2组呃逆患者不同时间点HAI评分比较(x±s，分)

Table 2. Comparison of HAI scores at different time points in two groups of patients with hiccups (x±s, points)

组别	例数	治疗前	第1次治疗后	第2次治疗后	第3次治疗后	F值	P值
中枢治疗组	36	9.92±0.37	6.69±2.07^a	3.64±3.08^ab	2.18±2.06^abc	78.453	0.001
外周治疗组	12	10.00±0.00	4.25±2.60^a	1.96±1.75^ab	0.45±0.36^abc	72.765	0.001
F值		0.778	3.324	2.576	3.142
P值		0.441	0.002	0.023	0.003
注：与同组治疗前比较，^aP＜0.05；与同组第1次治疗后比较，^bP＜0.05；与同组第2次治疗后比较，^cP＜0.05。

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