专科护理干预模式联合短波紫外线对鼻咽癌患者口腔黏膜损伤的影响

蒋青玉; 韦嘉章; 李湘; 黄晓艳; 李艳青

doi:10.16766/j.cnki.issn.1674-4152.003396

专科护理干预模式联合短波紫外线对鼻咽癌患者口腔黏膜损伤的影响

doi: 10.16766/j.cnki.issn.1674-4152.003396

广西壮族自治区人民医院耳鼻咽喉头颈科，广西南宁 530021

基金项目:

广西科技基地和人才专项基金桂科AD20297069

广西重点研发计划桂科AB16450009

广西卫健委自筹课题 Z-A20220018

广西卫健委自筹课题 Z20180753

广西卫健委自筹课题 Z20200481

广西卫健委自筹课题 Z-A20220027

详细信息

通讯作者:
李湘，E-mail: 52981063@qq.com

中图分类号: R739.6 R473.73
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出版历程
- 收稿日期: 2023-04-19
- 网络出版日期: 2024-03-27

Effect of specialized nursing interventions combined with short-wave ultraviolet light on oral mucosal injury in patients with nasopharyngeal carcinoma

Department of Otolaryngology & Head and Neck, the People ' s Hospital of Guangxi Zhuang Autonomous Region, Nanning, Guangxi 530021, China

摘要

摘要: 目的探讨鼻咽癌专科护理干预模式联合短波紫外线促进患者治疗过程中口腔黏膜创面愈合的疗效，为医疗工作者采取合理有效的治疗和干预模式提供依据。方法选取广西某三甲医院耳鼻咽喉头颈科2021年6月—2022年7月首次接受治疗的63例鼻咽癌患者为研究对象，按随机数字表分为对照组(31例)和观察组(32例)。对照组采用常规护理干预，观察组实施鼻咽癌专科护理干预模式，并在放疗出现口腔黏膜炎时采用短波紫外线治疗仪治疗。比较2组患者放疗期间口腔黏膜炎发生严重程度、康复时间、因口腔黏膜炎引起疼痛持续时间、住院时间。结果观察组口腔黏膜炎严重程度轻于对照组，口腔黏膜康复总时间[(10.9±0.9)d vs. (12.9±3.3)d]、口腔疼痛持续时间[(9.0±0.9)d vs. (11.0±3.0)d]、住院总时间[(59.5±3.4)d vs. (65.7±9.5)d]较对照组减少，差异均有统计学意义(P < 0.05)。结论鼻咽癌专科护理干预模式联合短波紫外线治疗可降低鼻咽癌放化疗患者口腔黏膜损伤的严重程度，加速口腔黏膜损伤的康复，减轻患者痛苦，缩短住院时间。
- 鼻咽癌 /
- 放化疗 /
- 口腔黏膜损伤 /
- 短波紫外线
Abstract: Objective To explore the effect of specialized nursing interventions combined with short-wave ultraviolet therapy on the oral mucosa of nasopharyngeal carcinoma (NPC) patients who undergoing radiotherapy and chemoradiotherapy. Methods Sixty-three patients with NPC who received treatment for the first time from June 2021 to July 2022 were selected and divided into the control group (n=31) and the observation group (n=32) according to the random number table. The control group received conventional nursing interventions, while the observation group received specialized nursing interventions combined with short-wave ultraviolet therapy when oral mucositis appeared during radiotherapy. The severity of oral mucositis during radiotherapy, recovery time, duration of pain caused by oral mucositis, and the days of hospitalization were compared between the groups. Results The severity of oral mucositis in the observation group was less than that in the control group. The total days of the recovery of oral mucosal [(10.9±0.9) d vs. (12.9±3.3) d], the duration of oral pain [(9.0±0.9) d vs. (11.0±3.0) d], and the total days of hospitalization [(59.5±3.4) d vs. (65.7±9.5) d] in the observation group were reduced as compared with the control group. The differences were statistically significant (P < 0.05). Conclusion Specialized nursing intervention combined with short-wave ultraviolet therapy can reduce the severity of oral mucosal injury, accelerate the recovery of oral mucosal injury, reduce pain, and shorten hospitalization.
- Nasopharyngeal carcinoma /
- Chemoradiotherapy /
- Oral mucosa injury /
- Short-wave ultraviolet light

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表 1 2组鼻咽癌放化疗患者一般资料比较

Table 1. Comparison of general data between two groups of nasopharyngeal carcinoma patients treated with radiotherapy and chemotherapy

组别	例数	性别(例)		年龄(x±s，岁)	文化程度(例)		临床分期(例)
组别	例数	男性	女性	年龄(x±s，岁)	高中及以下	高中以上	Ⅰ~Ⅱ期	Ⅲ~Ⅳ期
对照组	31	20	11	44.6±11.2	20	11	4	27
观察组	32	25	7	44.7±10.7	23	9	7	25
统计量		1.429^a		0.027^b	0.394^a		0.367^a
P值		0.232		0.979	0.530		0.545
注：^a为χ²值，^b为t值。

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表 2 2组鼻咽癌放化疗患者口腔黏膜损伤康复情况比较

Table 2. Recovery of oral mucosal damage in the two groups of patients with nasopharyngeal carcinoma undergoing radiotherapy

组别	例数	发生时间(x±s，d)	严重程度(例)		康复时间(x±s，d)	疼痛时间(x±s，d)	住院时间(x±s，d)
组别	例数	发生时间(x±s，d)	Ⅱ级	Ⅲ级	康复时间(x±s，d)	疼痛时间(x±s，d)	住院时间(x±s，d)
对照组	31	16.0±5.6	17	14	12.9±3.3	11.0±3.0	65.7±9.5
观察组	32	15.5±4.9	27	5	10.9±0.9	9.0±0.9	59.5±3.4
统计量		0.377^a	6.522^b		3.227^a	3.705^a	3.453^a
P值		0.707	0.011		0.004	0.001	0.001
注：^a为t值，^b为χ²值。

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