留言板

尊敬的读者、作者、审稿人, 关于本刊的投稿、审稿、编辑和出版的任何问题, 您可以本页添加留言。我们将尽快给您答复。谢谢您的支持!

姓名
邮箱
手机号码
标题
留言内容
验证码

消痔散联合艾盐包预防吻合器痔上黏膜切除术后尿潴留的回顾性研究

潘建丹 陈春丽 胡阿丽 蔡丹凤 汪少艳 郑阿芬 郑晨果

潘建丹, 陈春丽, 胡阿丽, 蔡丹凤, 汪少艳, 郑阿芬, 郑晨果. 消痔散联合艾盐包预防吻合器痔上黏膜切除术后尿潴留的回顾性研究[J]. 中华全科医学, 2024, 22(1): 21-25. doi: 10.16766/j.cnki.issn.1674-4152.003322
引用本文: 潘建丹, 陈春丽, 胡阿丽, 蔡丹凤, 汪少艳, 郑阿芬, 郑晨果. 消痔散联合艾盐包预防吻合器痔上黏膜切除术后尿潴留的回顾性研究[J]. 中华全科医学, 2024, 22(1): 21-25. doi: 10.16766/j.cnki.issn.1674-4152.003322
PAN Jiandan, CHEN Chunli, HU Ali, CAI Danfeng, WANG Shaoyan, ZHENG Afen, ZHENG Chenguo. Retrospective study of Xiaozhi Powder combined with moxa salt bag to prevent urinary retention after procedure for prolapse and hemorrhoids[J]. Chinese Journal of General Practice, 2024, 22(1): 21-25. doi: 10.16766/j.cnki.issn.1674-4152.003322
Citation: PAN Jiandan, CHEN Chunli, HU Ali, CAI Danfeng, WANG Shaoyan, ZHENG Afen, ZHENG Chenguo. Retrospective study of Xiaozhi Powder combined with moxa salt bag to prevent urinary retention after procedure for prolapse and hemorrhoids[J]. Chinese Journal of General Practice, 2024, 22(1): 21-25. doi: 10.16766/j.cnki.issn.1674-4152.003322

消痔散联合艾盐包预防吻合器痔上黏膜切除术后尿潴留的回顾性研究

doi: 10.16766/j.cnki.issn.1674-4152.003322
基金项目: 

国家自然科学基金项目 81704076

浙江省温州市科技局项目 Y20220671

详细信息
    通讯作者:

    潘建丹,E-mail: pjd969696@163.com

  • 中图分类号: R657.18

Retrospective study of Xiaozhi Powder combined with moxa salt bag to prevent urinary retention after procedure for prolapse and hemorrhoids

  • 摘要:   目的  回顾性研究中医治疗技术在预防吻合器痔上黏膜切除术(PPH)后尿潴留中的作用。  方法  选择2020年1月—2022年1月温州医科大学附属第二医院育英儿童医院收治的100例行PPH治疗的混合痔患者,按照治疗方式不同分为对照组(50例)和观察组(50例)。对照组术后给予常规西医治疗,观察组术后给予消痔散联合艾盐包治疗,比较2组治疗后中医证候积分、排尿情况、视觉模拟评分法(VAS)、尿动力学指标变化情况,统计2组治疗总有效率,评价治疗安全性。  结果  2组治疗后各项中医证候积分、术后8 h膀胱残余尿量均低于治疗前(P<0.05),且观察组治疗后均低于对照组(P<0.05);2组治疗后最大尿流量、充盈期逼尿肌压力、最大膀胱容量均高于治疗前(P<0.05),且观察组均高于对照组(P<0.05);观察组术后首次排尿时间、小腹膨满感消失时间及术后8 h尿潴留发生率均短于或低于对照组(P<0.05),首次排尿量多于对照组(P<0.05);观察组术后36 h的VAS评分低于对照组(P<0.05);观察组治疗的总有效率(92.0%,46/50)高于对照组(72.0%,36/50,χ2=6.775,P=0.009);2组均未出现明显药物不良反应。  结论  消痔散联合艾盐包能够有效调节PPH术后患者尿动力学指标,缓解腹胀、腹痛等不适症状,促进术后排尿,降低术后尿潴留的发生风险。

     

  • 表  1  2组PPH术后患者中医证候积分比较(x±s,分)

    Table  1.   Comparison of Traditional Chinese Medicine Syndrome Scores between Two Groups of Postoperative PPH Patients(x±s, points)

    组别 例数 小便滴沥不畅 腹胀 腹痛 每日小便量少
    治疗前 治疗后 治疗前 治疗后 治疗前 治疗后 治疗前 治疗后
    观察组 50 2.33±0.39 0.87±0.15a 2.29±0.37 0.83±0.13a 2.18±0.41 0.78±0.09a 2.11±0.39 0.73±0.10a
    对照组 50 2.31±0.40 1.28±0.31a 2.25±0.43 1.25±0.28a 2.16±0.39 1.22±0.25a 2.08±0.37 1.18±0.23a
    t 0.253 8.418 0.499 9.620 0.250 11.709 0.395 12.687
    P 0.801 <0.001 0.619 <0.001 0.803 <0.001 0.694 <0.001
    注:与同组治疗前比较,aP<0.05。
    下载: 导出CSV

    表  2  2组PPH术后患者基本临床指标比较

    Table  2.   Comparison of basic clinical indicators between two groups of PPH postoperative patients

    组别 例数 术后首次排尿时间(x±s,h) 首次排尿量(x±s,mL) 小腹膨满感消失时间(x±s,h) 术后8 h尿潴留发生[例(%)]
    对照组 50 4.95±0.61 189.92±27.71 4.31±0.45 11(22.0)
    观察组 50 2.45±0.35 243.55±30.08 2.98±0.50 2(4.0)
    统计量 25.136a 9.272a 13.987a 7.162b
    P <0.001 <0.001 <0.001 0.007
    注: at值,b为χ2值。
    下载: 导出CSV

    表  3  2组PPH术后患者VAS评分比较(x±s,分)

    Table  3.   Comparison of VAS scores between two groups of PPH postoperative patients(x±s, points)

    组别 例数 术后6 h 术后36 h
    对照组 50 6.52±0.55 2.05±0.31a
    观察组 50 6.55±0.57 0.82±0.19a
    t 0.335 21.149
    P 0.739 <0.001
    注:与同组术后6 h比较,aP<0.001。
    下载: 导出CSV

    表  4  2组PPH术后患者尿动力学指标比较(x±s)

    Table  4.   Comparison of urodynamic indicators between two groups of PPH postoperative patients(x±s)

    组别 例数 最大尿流量(mL/s) 充盈期逼尿肌压力(mmH2O) 最大膀胱容量(mL) 术后8 h膀胱残余尿量(mL)
    治疗前 治疗后 治疗前 治疗后 治疗前 治疗后 治疗前 治疗后
    观察组 50 6.52±1.30 13.67±1.56a 9.95±1.25 28.91±1.58a 230.81±26.45 455.65±30.71a 251.62±35.76 68.83±8.41a
    对照组 50 6.54±1.25 8.99±1.33a 9.93±1.22 17.79±1.38a 227.57±25.07 335.62±28.81a 247.71±34.41 125.56±19.91a
    t 0.078 16.143 0.081 37.482 0.629 20.156 0.557 18.560
    P 0.938 <0.001 0.936 <0.001 0.531 <0.001 0.579 <0.001
    注:与同组治疗前比较,aP<0.05;1 mmH2O=0.009 8 kPa。
    下载: 导出CSV

    表  5  2组PPH术后患者临床疗效比较[例(%)]

    Table  5.   Comparison of clinical efficacy between two groups of PPH postoperative patients[cases (%)]

    组别 例数 临床控制 显效 有效 无效 总有效
    对照组 50 12(24.0) 11(22.0) 13(26.0) 14(28.0) 36(72.0)
    观察组 50 17(34.0) 17(34.0) 12(24.0) 4(8.0) 46(92.0)
    注: 2组疗效比较,Z=-2.317,P=0.021。2组总有效率比较,χ2=6.775,P=0.009。
    下载: 导出CSV
  • [1] 桂阳, 刘丹峰. 吻合器痔上黏膜环切术与传统外剥内扎术治疗痔的疗效和安全性对比[J]. 皖南医学院学报, 2019, 38(5): 451-454. doi: 10.3969/j.issn.1002-0217.2019.05.012

    GUI Y, LIU D F. Comparing the efficacy and safety of procedure for prolapse and hemorrhoids and conventional Milligan-Morgan hemorrhoidectomy[J]. Acta Academiae Medicinae Wannan, 2019, 38(5): 451-454. doi: 10.3969/j.issn.1002-0217.2019.05.012
    [2] DE ROBLES M S, YOUNG C J. Surgical technique is the main predictor of recurrence in the management of haemorrhoids[J]. ANZ J Surg, 2021, 91(9): 1854-1858. doi: 10.1111/ans.16738
    [3] 章志霞, 李静, 潘兰兰, 等. 循经中药熨烫结合自我按摩预防混合痔术后尿潴留的临床观察[J]. 中国民间疗法, 2019, 27(7): 20-22. https://www.cnki.com.cn/Article/CJFDTOTAL-ZMJL201907012.htm

    ZHANG Z X, LI J, PAN L L, et al. Clinical Observation on the Prevention of Urinary Retention after Operation of Mixed Hemorrhoids by Traditional Chinese Medicine Pressing along Meridians and Self massage[J]. China's Naturopathy, 2019, 27(7): 20-22. https://www.cnki.com.cn/Article/CJFDTOTAL-ZMJL201907012.htm
    [4] 周喜, 熊燕萍, 谭伟能. 中药热罨包外敷神阙穴联合腹部按摩对预防混合痔PPH术后尿潴留的干预价值[J]. 内蒙古中医药, 2021, 40(1): 133-134. https://www.cnki.com.cn/Article/CJFDTOTAL-NZYY202101080.htm

    ZHOU X, XIONG Y P, TAN W N. Interventional value of external application of traditional Chinese medicine hot pouches on Shenque point combined with abdominal massage in preventing urinary retention after PPH for mixed hemorrhoids[J]. Nei Mongol Journal of Traditional Chinese Medicine, 2021, 40(1): 133-134. https://www.cnki.com.cn/Article/CJFDTOTAL-NZYY202101080.htm
    [5] 段文英. 腹腔镜胆囊切除术后女性患者发生尿潴留的危险因素分析[J]. 中国医学创新, 2020, 17(32): 151-155. doi: 10.3969/j.issn.1674-4985.2020.32.039

    DUAN W Y. Risk Factors of Urinary Retention in Female Patients after Laparoscopic Cholecystectomy[J]. Chinese Medical Innovation, 2020, 17(32): 151-155. doi: 10.3969/j.issn.1674-4985.2020.32.039
    [6] 陈婕妤, 盛莉莉, 陈俭, 等. 中药热熨联合中药灌肠治疗慢性盆腔炎(气滞血瘀型)的临床价值及对患者情绪的影响[J]. 山西医药杂志, 2023, 52(4): 243-246. https://www.cnki.com.cn/Article/CJFDTOTAL-SXYY202304001.htm

    CHEN J Y, SHENG L L, CHEN J, et al. Evaluation of the clinical efficacy of Chinese herbal hot pressing and Chinese herbal enema for the treatment of chronic inflammatory diseases of the pelvis(Types of Qi stagnation and congestion)and its effect on patients'mood[J]. Shanxi Medical Journal, 2023, 52(4): 243-246. https://www.cnki.com.cn/Article/CJFDTOTAL-SXYY202304001.htm
    [7] 中国中西医结合学会大肠肛门病专业委员会. 中国痔病诊疗指南(2020)[J]. 结直肠肛门外科, 2020, 26(5): 519-533. https://www.cnki.com.cn/Article/CJFDTOTAL-DCGM202204020.htm

    The Professional Committee of Colorectal and Anorectal Diseases of the Chinese Society of Integrated Traditional and Western Medicine. Chinese Guidelines for the Diagnosis and Treatment of Hemorrhoids (2020)[J]. Colorectal and anal surgery, 2020, 26(5): 519-533. https://www.cnki.com.cn/Article/CJFDTOTAL-DCGM202204020.htm
    [8] 郑筱萸. 中药新药临床研究指导原则(试行)[M]. 北京: 中国医药科技出版社, 2002: 90-105.

    ZHENG X Y. Guiding Principles for Clinical Research of New Traditional Chinese Medicine (Trial)[M]. Beijing: China Medical Science and Technology Press, 2002: 90-105.
    [9] 孙壮, 杨宇慎, 宫爱民. 肠镜下长城式切开环切法治疗吻合器痔上黏膜环切术术后重度吻合口狭窄的临床疗效[J]. 实用医学杂志, 2020, 36(4): 475-478. doi: 10.3969/j.issn.1006-5725.2020.04.011

    SUN Z, YANG Y S, GONG A M. Clinical efficacy analysis of colonoscopic assisted Great Wall type incision and ring-cut method for severe anastomotic stenosis after PPH[J]. The Journal of Practical Medicine, 2020, 36(4): 475-478. doi: 10.3969/j.issn.1006-5725.2020.04.011
    [10] 鲁振锋, 张秀峰, 沈忠, 等. 外剥内扎术联合荷包缝合术治疗Ⅲ、Ⅳ度混合痔的临床效果分析[J]. 中华全科医学, 2019, 17(4): 574-576, 604. doi: 10.16766/j.cnki.issn.1674-4152.000738

    LU Z F, ZHANG X F, SHEN Z, et al. Clinical effects of Milligan-Morgan hemorrhoidectomy combined with purse-string suture for grades Ⅲ-Ⅳ mixed hemorrhoid[J]. Chinese Journal of General Practice, 2019, 17(4): 574-576, 604. doi: 10.16766/j.cnki.issn.1674-4152.000738
    [11] 邵继华, 黄英, 陈芳. 吻合器痔上黏膜环切术治疗环状脱垂痔的疗效及术后发生尿潴留的影响因素[J]. 实用医学杂志, 2022, 38(23): 2986-2990. doi: 10.3969/j.issn.1006-5725.2022.23.017

    SHAO J H, HUANG Y, CHEN F. Efficacy of PPH in the treatment of circumferential prolapsed hemorrhoids and the influencing factors of postoperative urinary retention[J]. The Journal of Practical Medicine, 2022, 38(23): 2986-2990. doi: 10.3969/j.issn.1006-5725.2022.23.017
    [12] 刘泽洋, 白国民, 李彤, 等. 揿针联合全息刮痧防治混合痔吻合器痔上黏膜环切术后尿潴留临床观察[J]. 河北中医, 2023, 45(4): 613-616. https://www.cnki.com.cn/Article/CJFDTOTAL-HBZY202304020.htm

    LIU Z Y, BAI G M, LI T, et al. Curative effect of press-needle combined with holographic scraping on postoperative urinary retention in mixed hemorrhoid patients underwent procedure for prolapse and hemorrhoids[J]. Hebei Journal of Traditional Chinese Medicine, 2023, 45(4): 613-616. https://www.cnki.com.cn/Article/CJFDTOTAL-HBZY202304020.htm
    [13] 刘聪聪, 刘剑, 于航, 等. 肛肠病术后尿潴留的防治研究进展[J]. 中国肛肠病杂志, 2020, 40(12): 76-78. https://www.cnki.com.cn/Article/CJFDTOTAL-GCBZ202012037.htm

    LIU C C, LIU J, YU H, et al. Research progression on preventing&treating uroschesis following surgery for coloproctological diseases[J]. Chinese Journal of Coloproctology, 2020, 40(12): 76-78. https://www.cnki.com.cn/Article/CJFDTOTAL-GCBZ202012037.htm
    [14] 李荣华, 蔡靓羽, 蒋晨浩, 等. 吻合器痔上黏膜环切术前揿针埋针对患者术后尿潴留发生的影响[J]. 山东医药, 2020, 60(20): 70-72. https://www.cnki.com.cn/Article/CJFDTOTAL-SDYY202020019.htm

    LI R H, CAI J Y, JIANG C H, et al. The effect of pressing needle embedding before stapler hemorrhoidectomy on postoperative urinary retention[J]. Shandong Medical Journal, 2020, 60(20): 70-72. https://www.cnki.com.cn/Article/CJFDTOTAL-SDYY202020019.htm
    [15] HIRAKI M, TANAKA T, SADASHIMA E, et al. The risk factors of acute urinary retention after laparoscopic colorectal cancer surgery in elderly patients receiving epidural analgesia[J]. Int J Colorectal Dis, 2021, 36(9): 1853-1859.
    [16] PATEL P M, SERIGERT S E, NELSON M, et al. Disparities in benign prostatic hyperplasia progression: predictors of presentation to the emergency department in urinary retention[J]. J Urol, 2020, 204(2): 332-335.
    [17] FRENDL D M, CHEN Y W, CHANG D C, et al. A claims based assessment of reoperation and acute urinary retention after ambulatory transurethral surgery for benign prostatic hyperplasia[J]. J Urol, 2021, 205(2): 532-538.
    [18] 陈文鹏, 卢健棋, 庞延, 等. 仙鹤草化学成分、药理作用及临床应用研究进展[J]. 辽宁中医药大学学报, 2022, 24(6): 118-122. https://www.cnki.com.cn/Article/CJFDTOTAL-LZXB202206026.htm

    CHEN W P, LU J Q, PANG Y, et al. Research Progress on Chemical Constituents Pharmacological Action and Clinical Application of Xianhecao (Agrimoniae Herba)[J]. Journal of Liaoning University of Traditional Chinese Medicine, 2022, 24(6): 118-122. https://www.cnki.com.cn/Article/CJFDTOTAL-LZXB202206026.htm
    [19] 刘琳, 程伟. 槐花化学成分及现代药理研究新进展[J]. 中医药信息, 2019, 36(4): 125-128. https://www.cnki.com.cn/Article/CJFDTOTAL-ZYXN201904035.htm

    LIU L, CHENG W. Research Progress in Chemical Constituents and Modern Pharmacology of Sophora japonica[J]. Information on Traditional Chinese Medicine, 2019, 36(4): 125-128. https://www.cnki.com.cn/Article/CJFDTOTAL-ZYXN201904035.htm
    [20] 董庆海, 吴福林, 王涵, 等. 延胡索药学研究进展[J]. 中国野生植物资源, 2019, 38(1): 48-53, 79. https://www.cnki.com.cn/Article/CJFDTOTAL-ZYSZ201901013.htm

    DONG Q H, WU F L, WANG H, et al. Advances in Pharmaceutical Research of Corydalis Yanhusuo[J]. Chinese Wild Plant Resources, 2019, 38(1): 48-53, 79. https://www.cnki.com.cn/Article/CJFDTOTAL-ZYSZ201901013.htm
  • 加载中
表(5)
计量
  • 文章访问数:  56
  • HTML全文浏览量:  23
  • PDF下载量:  10
  • 被引次数: 0
出版历程
  • 收稿日期:  2023-09-11
  • 网络出版日期:  2024-03-09

目录

    /

    返回文章
    返回