A randomized controlled study of warm needle ginger moxibustion combined with Xingnao Kaiqiao acupuncture method in treatment of urinary incontinence after stroke
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摘要:
目的 尿失禁是脑卒中后常见的后遗症,本研究采用温针隔姜灸联合“醒脑开窍”针刺法治疗脑卒中后尿失禁,旨在寻找更有效治疗脑卒中后尿失禁的方法。 方法 选择2021年1月—2022年6月在浙江中医药大学附属金华中医院就诊的45例采用温针隔姜灸联合“醒脑开窍”针刺法治疗的脑卒中尿失禁患者作为观察组,再同期纳入45例采用“醒脑开窍”针刺法治疗的脑卒中尿失禁患者作为对照组。比较2组临床疗效、不良事件及治疗前后各项评分的变化。 结果 观察组临床总有效率明显高于对照组;治疗2周、4周及1个月、3个月时,观察组国际尿失禁咨询委员会问卷简表评分(14.52±3.16,10.49±3.20,9.24±2.47,7.63±2.34 vs. 14.68±3.41,12.23±2.66,11.50±1.97,10.33±2.62)、夜间尿失禁程度分级评分(3.71±1.23,3.06±1.28,2.26±0.87,2.59±0.73 vs. 4.54±1.66,4.13±1.85,3.41±0.96,3.29±0.87)、膀胱残余尿量水平明显低于对照组,最大逼尿肌压、最大尿流率、最大膀胱容量、单次尿量水平明显高于对照组(均P < 0.05)。 结论 温针隔姜灸联合“醒脑开窍”针刺法治疗脑卒中后尿失禁可有效改善排尿功能,降低尿失禁及夜间尿失禁程度,且安全性较好。 Abstract:Objective Urinary incontinence is a common sequela after stroke. In this study, warm acupuncture and ginger moxibustion combined with Xingnao Kaiqiao acupuncture were used to treat urinary incontinence after stroke, aiming to find a more effective treatment method for urinary incontinence after stroke. Methods A total of 45 patients with stroke and urinary incontinence treated with warm needle and ginger moxibustion combined with Xingnao Kaiqiao acupuncture method were selected as the observation group from January 2021 to June 2022 in Jinhua Hospital of Traditional Chinese Medicine Affiliated to Zhejiang University of Chinese Medicine, and 45 patients with stroke and urinary incontinence treated with Xingnao Kaiqiao acupuncture method were enrolled as the control group during the same period. The clinical efficacy, adverse events and scores before and after treatment were compared between the two groups. Results The total effective rate of clinical efficacy in the observation group was significantly higher than that in the control group. At 2, 4 weeks, 1 and 3 months of treatment, international continence advisory committee urinary incontinence questionnaire short form (ICIQ-SF) score (14.52±3.16, 10.49±3.20, 9.24±2.47, 7.63±2.34 vs. 14.68±3.41, 12.23±2.66, 11.50±1.97, 10.33±2.62), nocturnal incontinence grade score (3.71±1.23, 3.06±1.28, 2.26±0.87, 2.59±0.73 vs. 4.54±1.66, 4.13±1.85, 3.41±0.96, 3.29±0.87) and residual urinary volume of the observation group were significantly lower than those of the control group, while the maximum detrusor muscle pressure, maximum urine flow rate, maximum bladder volume and single urine volume in observation group were significantly higher than those in control group (all P < 0.05). Conclusion Warm needle ginger moxibustion combined with Xingnao Kaiqiao acupuncture and pelvic floor muscle function training in the treatment of urinary incontinence after stroke can effectively improve urination function, reduce the degree of urinary incontinence and nocturnal urinary incontinence, and the security is better. -
表 1 2组脑卒中后尿失禁患者一般资料比较
Table 1. Comparison of general data of urinary incontinence patients after stroke in two groups
组别 例数 性别(例) 年龄(x±s, 岁) 脑卒中种类(例) 脑卒中病程(x±s, 周) 日均排尿次数(x±s, 次) 尿失禁分级(例) 尿失禁病程(x±s, 周) 男性 女性 脑出血 脑梗死 Ⅰ级 Ⅱ级 Ⅲ级 Ⅳ级 对照组 45 27 18 68.49±7.21 20 25 14.25±3.48 7.42±2.56 6 12 17 10 18.75±4.82 观察组 45 21 24 67.53±8.42 26 19 13.89±4.51 7.19±2.97 11 9 20 5 19.14±5.30 统计量 1.607a 0.581b 1.601a 0.424b 0.393b -1.199c 0.365b P值 0.205 0.563 0.206 0.673 0.694 0.230 0.716 注:a为χ2值,b为t值,c为Z值。 表 2 2组脑卒中后尿失禁患者临床总有效率比较[例(%)]
Table 2. Comparison of clinical total effective rate of urinary incontinence patients after stroke in two groups[cases (%)]
组别 例数 治愈 显效 有效 无效 总有效 对照组 45 11(24.44) 16(35.56) 5(11.11) 13(28.89) 32(71.11) 观察组 45 19(42.22) 8(17.78) 14(31.11) 4(8.89) 41(91.11) 注:2组总有效率比较,χ2=23.728,P < 0.001。 表 3 2组脑卒中后尿失禁患者治疗前后ICIQ-SF评分比较(x±s,分)
Table 3. Comparison of ICIQ-SF scores of patients with urinary incontinence after stroke in two groups before and after treatment(x±s, points)
组别 例数 治疗前 治疗2周 治疗4周 治疗1个月 治疗3个月 观察组 45 16.96±2.53 14.52±3.16a 10.49±3.20a 9.24±2.47a 7.63±2.34a 对照组 45 17.05±2.69 14.68±3.41a 12.23±2.66a 11.50±1.97a 10.33±2.62a t值 -0.163 -0.188 -2.805 -4.799 -5.156 P值 0.871 0.852 0.006 < 0.001 < 0.001 注:与治疗前比较,aP < 0.05。 表 4 2组脑卒中后尿失禁患者治疗前后排尿指标比较(x±s)
Table 4. Comparison of urinary indexes of patients with urinary incontinence after stroke in two groups before and after treatment(x±s)
组别 例数 最大逼尿肌压(cm/H2O) 治疗前 治疗2周 治疗4周 治疗1个月 治疗3个月 观察组 45 9.16±1.15 10.60±0.72ab 11.32±0.91ab 12.38±0.84ab 13.47±1.46ab 对照组 45 9.28±0.71 9.73±0.76a 10.05±0.37a 10.42±1.44a 11.72±1.85a 组别 例数 最大尿流率(mL/s) 治疗前 治疗2周 治疗4周 治疗1个月 治疗3个月 观察组 45 12.34±1.03 15.00±0.56ab 15.27±0.96ab 16.14±0.82ab 18.23±1.31ab 对照组 45 12.11±1.04 13.99±0.37a 14.15±0.72a 15.25±0.72a 16.15±0.94a 组别 例数 最大膀胱容量(mL) 治疗前 治疗2周 治疗4周 治疗1个月 治疗3个月 观察组 45 204.82±7.10 221.76±5.97ab 223.00±10.07ab 244.39±10.71ab 300.54±10.95ab 对照组 45 203.54±6.34 211.81±8.50a 217.26±6.11a 230.63±9.10a 289.05±10.29a 组别 例数 单次尿量(mL) 治疗前 治疗2周 治疗4周 治疗1个月 治疗3个月 观察组 45 128.49±4.96 135.62±8.45ab 143.84±6.19ab 142.90±8.27ab 145.44±7.01ab 对照组 45 125.91±6.97 131.32±6.01a 131.43±6.23a 133.74±6.76a 134.78±5.93a 组别 例数 膀胱残余尿量(mL) 治疗前 治疗2周 治疗4周 治疗1个月 治疗3个月 观察组 45 74.78±5.79 64.71±6.06ab 62.16±5.02ab 41.06±5.45ab 30.17±4.83ab 对照组 45 73.98±6.36 68.94±8.08a 64.99±6.48a 49.50±8.72a 38.46±6.04a 注:与治疗前比较,aP < 0.05;与对照组比较,bP < 0.05。 表 5 2组脑卒中后尿失禁患者治疗前后夜间尿失禁程度分级评分比较(x±s,次)
Table 5. Comparison of nocturnal urinary incontinence grade scores of patients with urinary incontinence after stroke in two groups before and after treatment(x±s, times)
组别 例数 治疗前 治疗2周 治疗4周 治疗1个月 治疗3个月 观察组 45 5.84±2.48 3.71±1.23a 3.06±1.28a 2.26±0.87a 2.59±0.73a 对照组 45 6.12±1.78 4.54±1.66a 4.13±1.85a 3.41±0.96a 3.29±0.87a t值 -0.615 -2.695 -3.191 -5.954 -4.135 P值 0.540 0.008 0.002 < 0.001 < 0.001 注:与治疗前比较,aP < 0.05。 -
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