中医体质与血脂、尿酸、体重指数等的相关性研究

郑美鸿; 张斌; 李东彩; 梁绮君; 董承煊; 潘智斌; 关锦图; 徐光镇; 刘继洪

doi:10.16766/j.cnki.issn.1674-4152.003175

中医体质与血脂、尿酸、体重指数等的相关性研究

doi: 10.16766/j.cnki.issn.1674-4152.003175

广州中医药大学附属佛山中医院治未病中心，广东佛山 528000

基金项目:

广东省中医药局科研项目 20223038

详细信息

通讯作者:
刘继洪，E-mail：544279373@qq.com

中图分类号: R241 R589.2
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- 文章访问数: 159
- HTML全文浏览量: 35
- PDF下载量: 6
- 被引次数: 0
出版历程
- 收稿日期: 2023-03-15
- 网络出版日期: 2023-10-19

Study on the correlation between TCM constitution and blood lipid, uric acid and body mass index

Department of Preventive Treatment of Disease, FoShan Hospital of Traditional Chinese Medicine Affiliated to Guangzhou University of Traditional Chinese Medicine, Foshan, Guangdong 528000, China

摘要

摘要: 目的探讨中医体质与血脂、体重指数、尿酸、脂肪含量的相关性，分析影响血脂异常发生的危险因素。方法选取2019年1月—2020年12月在佛山市中医院体检的1 061例人群进行横断面回顾性研究，运用SPSS 24.0统计学软件分析不同体质者的血脂、尿酸、体重指数和脂肪含量的相关性以及血脂异常和超重/肥胖发生率，采用二元logistic回归分析方法分析血脂异常发生的危险因素。结果 1 061例体检人群中，平和质300例(28.28%)，偏颇体质761例(71.73%)，其中，偏颇体质中痰湿质202例(19.04%)，阳虚质172例(16.21%)，气虚质136例(12.82%)；男性痰湿质占比高于女性，女性气郁质、阴虚质和血瘀质占比高于男性(均P＜0.05)；偏颇质者TC、LDL-C、BMI高于平和质者(均P＜0.05)；与平和质相比较，痰湿质者TG、LDL-C、BMI偏高，HDL-C偏低，湿热质者LDL-C、BMI、脂肪含量偏高，气郁质者BMI偏低(均P＜0.05)；痰湿质和湿热质者超重/肥胖发生率高于平和质者(均P＜0.05)；男性患血脂异常的风险是女性的2.521倍，尿酸偏高者患血脂异常的风险是尿酸正常者的1.808倍，脂肪含量、BMI水平与血脂异常呈正相关关系(均P＜0.05)。结论性别为男性，高UA、高BMI和脂肪含量偏高是影响血脂异常发生的危险因素，纠正偏颇体质和控制体重有助于减少血脂异常和超重/肥胖的发生。
- 中医体质 /
- 体重指数 /
- 血脂异常 /
- 超重/肥胖
Abstract: Objective To explore the correlation between traditional Chinese medicine (TCM) constitution and blood lipid, body mass index, uric acid and fat content, and analyze the risk factors affecting the occurrence of dyslipidemia. Methods A cross-sectional retrospective study was conducted on 1 061 patients who underwent physical examination in Foshan Hospital of Traditional Chinese Medicine from January 2019 to December 2020. SPSS 24.0 statistical software was used to analyze the correlation between blood lipid, uric acid, body mass index and fat content of people with different physical conditions, as well as the incidence of dyslipidemia and overweight/obesity. Binary logistic regression analysis was used to analyze the risk factors of dyslipidemia. Results Among the 1 061 cases of physical examination, 300 cases (28.28%) of peaceful constitution, 761 cases (71.73%) of biased constitution, of which 202 cases (19.04%) of phlegm-wet, 172 cases (16.21%) of Yang deficiency, 136 cases (12.82%) of qi deficiency; The proportion of phlegm-wet in male was higher than that in female, and the proportion of Qi-stagnation, Yin deficiency and blood stasis in female was higher than that in male (all P < 0.05).The TC, LDL-C and BMI of the biased constitution were higher than those of the peaceful constitution (all P < 0.05). TG, LDL-C and BMI were higher and HDL-C was lower in phlegm-wet patients, LDL-C, BMI and fat contents were higher in damp-heat patients, and BMI was lower in Qi-stagnation patients (all P < 0.05). The incidence of overweight/obesity was higher in phlegm-wet and damp-heat constitution than in peaceful constitution (all P < 0.05). The risk of dyslipidemia in males was 2.521 times higher than that in females, and the risk of dyslipidemia in those with high uric acid was 1.808 times higher than that of those with normal uric acid. Fat content and BMI were positively correlated with dyslipidemia (all P < 0.05). Conclusion Sex for male, high uric acid, high BMI and high fat content are risk factors for dyslipidemia. Correcting biased constitution and controlling weight can help reduce the occurrence of dyslipidemia and overweight/obesity.
- Constitution of TCM /
- Body mass index /
- Dyslipidemia /
- Overweight/obesity

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表 1 1 061名体检人员不同体质类型的分布情况

Table 1. Distribution of different types of TCM constitution of 1 061 physical examination personnel

体质类型	频数	构成比(%)
平和质	300	28.28
痰湿质	202	19.04
阳虚质	172	16.21
气虚质	136	12.82
湿热质	100	9.43
气郁质	66	6.22
阴虚质	41	3.86
血瘀质	32	3.02
特禀质	12	1.13

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表 2 1 061名体检人员不同性别的体质分布情况[例(%)]

Table 2. Distribution of TCM constitution types of 1 061 physical examination personnel in different genders

性别	例数	平和质	痰湿质	阳虚质	气虚质	湿热质	气郁质	阴虚质	血瘀质	特禀质
男性	612	175(28.6)	133(21.7)	103(16.8)	86(14.1)	61(10.0)	26(4.2)	10(1.6)	8(1.3)	10(1.6)
女性	449	125(27.8)	69(15.4)	69(15.4)	50(11.1)	39(8.7)	40(8.9)	31(6.9)	24(5.3)	2(0.4)
χ²值		0.041	4.671	0.295	1.530	0.413	8.460	17.795	13.516	3.205
P值		0.840	0.031	0.587	0.216	0.520	0.005	＜0.001	＜0.001	0.084

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表 3 不同形体肥胖程度体检人员的中医体质分布情况[例(%)]

Table 3. Distribution of TCM constitution types in physical examination personnel with different body obesity degree[cases (%)]

组别	例数	平和质	痰湿质	阳虚质	气虚质	湿热质	气郁质	阴虚质	血瘀质	特禀质
正常/偏瘦	638	190(29.8)	101(15.8)	106(16.6)	79(12.4)	51(8.0)	51(8.0)	32(5.0)	23(3.6)	5(0.8)
超重/肥胖	423	110(26.0)	101(23.9)	66(15.6)	57(13.5)	49(11.6)	15(3.5)	9(2.1)	9(2.1)	7(1.7)
χ²值		1.006	7.176	0.138	0.210	3.159	7.683	5.317	1.792	1.685
P值		0.316	0.007	0.710	0.647	0.076	0.006	0.021	0.181	0.194

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表 4 不同体质体检人员的血脂和尿酸的比较(x±s)

Table 4. Comparison of blood lipid and uric acid in physical examination personnel of different TCM constitution types(x±s)

体质类型	例数	TCH (mmol/L)	TG (mmol/L)	LDL-C (mmol/L)	HDL-C (mmol/L)	UA (μmol/L)
平和质	300	4.79±0.89	1.40±1.30	2.76±0.80	1.30±0.32	369.63±95.97
痰湿质	202	4.93±0.96	1.64±1.29^a	2.94±0.78^a	1.24±0.27^a	384.90±105.43
阳虚质	172	4.94±0.93	1.53±1.16	2.87±0.76	1.29±0.28	365.06±104.43
气虚质	136	5.02±1.03	1.52±1.20	2.87±0.85	1.32±0.38	368.15±108.85
湿热质	100	4.89±0.94	1.40±0.90	2.95±0.81^a	1.28±0.26	390.36±94.48
气郁质	66	4.79±0.92	1.18±0.75	2.71±0.74	1.37±0.36	357.53±96.96
阴虚质	41	4.91±0.79	1.07±0.55	2.84±0.64	1.39±0.39	320.09±92.10^a
血瘀质	32	4.65±0.79	1.12±0.66	2.53±0.65	1.49±0.31^a	302.71±76.99^a
F值		1.525	2.479	2.394	3.601	4.683
P值		0.144	0.012	0.015	＜0.001	＜0.001
注：与平和质比较，^aP＜0.05。

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表 5 不同体质体检人员BMI、脂肪含量、体脂百分比、内脏脂肪等级的比较(x±s)

Table 5. Comparison of BMI, fat content, body fat percentage and visceral fat grade in physical examination personnel of different TCM constitution types(x±s)

体质类型	例数	BMI	脂肪含量(kg)	体脂百分比(%)	内脏脂肪等级
平和质	300	22.80±3.57	15.81±6.33	24.94±7.78	6.32±3.17
痰湿质	202	23.83±3.64^a	16.77±6.56	25.50±7.17	6.68±3.40
阳虚质	172	23.33±4.08	16.58±7.40	25.52±8.07	6.65±3.64
气虚质	136	23.19±3.85	16.17±6.92	25.04±7.43	6.34±3.64
湿热质	100	24.20±3.87^a	17.88±7.35^a	26.46±7.52	7.32±3.83
气郁质	66	21.78±3.09^a	15.03±5.60	25.88±7.48	6.05±3.09
阴虚质	41	22.04±2.59	15.68±5.83	27.49±7.72	6.59±3.54
血瘀质	32	22.80±2.86	16.52±5.76	28.28±7.81	6.88±3.39
F值		4.892	2.281	1.467	1.790
P值		＜0.001	0.020	0.165	0.075
注：与平和质比较，^aP＜0.05。

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表 6 平和质和偏颇质体检人员之间的血脂、尿酸及BMI的比较(x±s)

Table 6. Comparison of blood lipid, uric acid and BMI in physical examination personnel between peaceful constitution and biased constitution(x±s)

组别	例数	TC(mmol/L)	TG(mmol/L)	HDL-C(mmol/L)	LDL-C(mmol/L)	UA(μmol/L)	BMI
平和质	300	4.79±0.89	1.41±1.30	1.30±0.32	2.76±0.80	368.35±98.43	22.80±3.57
偏颇质	761	4.91±0.95	1.47±1.11	1.50±5.62	2.88±0.78	372.40±139.05	23.37±3.77
t值		-2.086	-0.820	-1.006	-2.058	-0.532	-2.289
P值		0.037	0.413	0.315	0.040	0.595	0.022

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表 7 不同体质体检人员的血脂异常、超重/肥胖发生率比较[例(%)]

Table 7. Comparison of the incidence of dyslipidemia and overweight/obesity in physical examination personnel of different TCM constitution types[cases (%)]

体质类型	例数	血脂异常	χ²值^a	P值^a	超重/肥胖	χ²值^a	P值^a
平和质	300	183(61.00)			110(36.67)
痰湿质	202	128(63.37)	0.287	0.592	101(50.00)	8.808	0.003
阳虚质	172	108(62.79)	0.148	0.700	66(38.37)	0.136	0.712
气虚质	136	83(61.03)	< 0.001	0.995	55(40.44)	0.567	0.452
湿热质	100	65(65.00)	0.509	0.475	49(49.00)	4.764	0.029
气郁质	66	36(54.55)	0.938	0.333	15(22.73)	4.674	0.031
阴虚质	41	25(60.98)	< 0.001	0.998	9(21.95)	3.438	0.064
血瘀质	32	14(43.75)	3.566	0.059	9(28.13)	0.917	0.338
注：^a为与平和质比较。

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表 8 体检人员血脂异常发生风险的二元logistic回归分析

Table 8. Binary logistic regression analysis of the risk of dyslipidemia in physical examination personnel

变量	B	SE	Wald χ²	P值	OR值	95% CI
男性	0.924	0.240	14.860	＜0.001	2.521	1.575~4.033
BMI	0.105	0.048	4.737	0.030	1.110	1.010~1.220
尿酸偏高	0.592	0.159	13.852	＜0.001	1.808	1.323~2.469
脂肪含量	0.131	0.058	5.143	0.023	1.140	1.018~1.277

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