S-Detect技术与应变弹性成像对C-TI-RADS 4A类甲状腺结节的诊断价值

郑志燕; 叶新华; 章东

doi:10.16766/j.cnki.issn.1674-4152.002994

S-Detect技术与应变弹性成像对C-TI-RADS 4A类甲状腺结节的诊断价值

doi: 10.16766/j.cnki.issn.1674-4152.002994

郑志燕^{1, 2},
叶新华^1, ,,
章东³

1.
南京医科大学第一附属医院超声医学科, 江苏南京 210029
2.
安徽医科大学附属滁州医院(滁州市第一人民医院)超声中心，安徽滁州 239000
3.
南京大学声学研究所近代声学教育部重点实验室，江苏南京 210093

基金项目:

江苏省级重点研发计划项目 BE2018703

详细信息

通讯作者:
叶新华, E-mail: yexh-0125@163.com

中图分类号: R445.1 R736.1
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- 文章访问数: 330
- HTML全文浏览量: 200
- PDF下载量: 12
- 被引次数: 0
出版历程
- 收稿日期: 2022-09-06

Diagnosis value of S-Detect technique and strain elastography for C-TI-RADS 4A thyroid nodules

ZHENG Zhiyan^{1, 2},
YE Xinhua^{1
, ,},
ZHANG Dong³

1.
Department of Ultrasound Diagnostics, the First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu 210029, China

摘要

摘要: 目的评估S-Detect技术与应变弹性成像对C-TI-RADS 4A类甲状腺结节的再分类，探讨二者对C-TI-RADS 4A类甲状腺结节的诊断价值。方法选取2021年4月—2022年4月在南京医科大学第一附属医院超声诊断科常规超声检查报告为C-TI-RADS 4A类且有明确病理结果的87例患者共102个结节，应用三星S-Detect技术与应变弹性成像对结节辅助诊断重新分类，比较S-Detect技术、应变弹性成像及2种方法协助人工再分类诊断结果与病理结果的一致性，以及2种方法对C-TI-RADS 4A类结节的诊断效能。结果 2种方法诊断结果与病理结果具有一致性，S-Detect技术与病理结果的一致性(Kappa=0.652，P < 0.001)高于应变弹性成像(Kappa=0.381，P < 0.001)，2种方法协助人工再分类与病理结果的一致性(Kappa=0.510，P < 0.001)介于二者之间，S-Detect技术和应变弹性成像对C-TI-RADS 4A类结节良恶性诊断的灵敏度、特异度、准确度分别为93.10%、70.45%、83.33%和62.07%、77.27%、68.63%。S-Detect技术诊断C-TI-RADS 4A类结节的灵敏度、准确度高于应变弹性成像(均P < 0.05)，而两者诊断的特异度比较差异无统计学意义(P > 0.05)。结论 S-Detect技术与应变弹性成像作为辅助性诊断方法，对C-TI-RADS 4A类结节的诊断与病理结果均具有一致性，且前者一致性高。
- 超声 /
- S-Detect /
- 应变弹性成像 /
- 甲状腺结节 /
- C-TI-RADS
Abstract: Objective Evaluate the reclassification of C-TI-RADS 4A thyroid nodules using S-Detect technology and strain elastography, and explore their diagnostic value for C-TI-RADS 4A thyroid nodules. Methods A total of 102 nodules were selected from 87 patients of C-TI-RADS 4A with clear-defined pathological results from April 2021 to April 2022 in the routine ultrasound examination of the First Affiliated Hospital of Nanjing Medical University. Samsung S-Detect technology and strain elastography were used to aid in the reclassification of nodules. The consistency between S-Detect technology, strain elastography, two methods to assist in manual reclassification diagnosis and pathological results was compared, as well as the diagnostic efficacy of the two methods for C-TI-RADS 4A type nodules. Results The diagnostic results of the two methods were consistent with the pathological results, the consistency between S-Detect technology and the pathological results (Kappa=0.652, P < 0.001) was higher than that of strain elastography (Kappa=0.381, P < 0.001), the consistency between the manual reclassification assisted by the two methods and the pathological results (Kappa=0.510, P < 0.001) was between the two methods. The sensitivity, specificity and accuracy of S-Detect technology and strain elastography for the benign and malignant diagnosis of C-TI-RADS 4A nodules were 93.10%, 70.45%, 83.33% and 62.07%, 77.27% and 68.63%, respectively. The sensitivity and accuracy of S-Detect technology in diagnosing C-TI-RADS 4A nodules was higher than that of strain elastography (all P < 0.05), however, the specificity of the two methods was not statistically significant (P > 0.05). Conclusion The S-Detect technique and strain elastography, as an assisted diagnostic method, have consistent diagnostic results of C-TI-RADS 4A type nodules with pathological results, and the S-Detect technique has high consistency.
- Ultrasound /
- S-Detect /
- Strain elastography /
- Thyroid nodules /
- C-TI-RADS
利益冲突 无

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图 1 S-Detect技术与应变弹性成像对C-TI-RADS 4A类结节的诊断与病理对照

注：A示S-Detect技术诊断为可能良性，降为3类；B示应变弹性成像评分为2分，视为良性，降为3类；C示病理结果为甲状腺乳头状癌，镜下可见核拉长、重叠、拥挤，并见核沟、核内包涵体(HE，×100)。

Figure 1. Comparison of diagnosis and pathology of C-TI-RADS 4A nodules by S-Detect and strain elastography

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图 2 S-Detect技术与应变弹性成像对C-TI-RADS 4A类结节的诊断与病理对照

注：A示S-Detect技术诊断为可能恶性，分类不变；B示应变弹性成像评分为2分，视为良性，降为3类；C示病理结果为亚急性甲状腺炎，镜下可见部分滤泡被破坏，胶质外溢，肉芽肿形成及炎细胞浸润(HE，×40)。

Figure 2. Comparison of diagnosis and pathology of C-TI-RADS 4A nodules by S-Detect and strain elastography

下载: 全尺寸图片幻灯片

表 1 不同方法诊断结果与病理结果的一致性比较

Table 1. Comparison of consistency between diagnostic results of different methods and pathological results

方法		病理结果			Kappa	P值
方法		恶性	良性	合计	Kappa	P值
S-Detect	恶性	54	13	67	0.652	< 0.001
	良性	4	31	35
	合计	58	44	102
应变弹性成像	恶性	36	10	46	0.381	< 0.001
	良性	22	34	56
	合计	58	44	102
人工再分类	恶性	34	2	36	0.510	< 0.001
	良性	24	42	66
	合计	58	44	102

下载: 导出CSV

表 2 S-Detect技术与应变弹性成像对C-TI-RADS 4A类结节诊断效能分析

Table 2. Analysis of diagnostic efficacy of S-Detect technology and strain elastography for C-TI-RADS 4A nodules

方法	灵敏度(%)		特异度(%)		准确度(%)
方法	数值	95% CI	数值	95% CI	数值	95% CI
S-Detect	93.10	82.45~97.77	70.45	54.61~82.75	83.33	74.66~89.98
应变弹性成像	62.07	48.35~74.19	77.27	61.78~88.01	68.63	58.69~77.45
χ²值	13.136		0.211		5.488
P值	< 0.001		0.648		0.028

下载: 导出CSV

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