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新生儿重症监护室患儿压力性损伤现状及相关危险因素分析

冯哲 王洋 兰端云 易靖 鞠敏

冯哲, 王洋, 兰端云, 易靖, 鞠敏. 新生儿重症监护室患儿压力性损伤现状及相关危险因素分析[J]. 中华全科医学, 2022, 20(10): 1708-1710. doi: 10.16766/j.cnki.issn.1674-4152.002685
引用本文: 冯哲, 王洋, 兰端云, 易靖, 鞠敏. 新生儿重症监护室患儿压力性损伤现状及相关危险因素分析[J]. 中华全科医学, 2022, 20(10): 1708-1710. doi: 10.16766/j.cnki.issn.1674-4152.002685
FENG Zhe, WANG Yang, LAN Duan-yun, YI Jing, JU Min. Current status and related risk factors of stress injury in children in neonatal intensive care unit[J]. Chinese Journal of General Practice, 2022, 20(10): 1708-1710. doi: 10.16766/j.cnki.issn.1674-4152.002685
Citation: FENG Zhe, WANG Yang, LAN Duan-yun, YI Jing, JU Min. Current status and related risk factors of stress injury in children in neonatal intensive care unit[J]. Chinese Journal of General Practice, 2022, 20(10): 1708-1710. doi: 10.16766/j.cnki.issn.1674-4152.002685

新生儿重症监护室患儿压力性损伤现状及相关危险因素分析

doi: 10.16766/j.cnki.issn.1674-4152.002685
基金项目: 

河南省科技攻关项目 192103210073

南阳市科技攻关项目 KJGG20134

详细信息
    通讯作者:

    冯哲, E-mail: fengzhe8806@163.com

  • 中图分类号: R722R473.72

Current status and related risk factors of stress injury in children in neonatal intensive care unit

  • 摘要:   目的  了解新生儿重症监护室(NICU)压力性损伤的发生现状、分布特点及危险因素。  方法  选取2019年1—12月南阳市中心医院新生儿重症监护室收治的467例患儿,收集相关人口学资料、病情、压力性损伤发生部位及体征等,对影响患儿发生压力性损伤的相关危险因素进行logistic回归分析。  结果  在467例患儿中,有79例(93处)发生不同程度的压力性损伤,压力性损伤发生率为16.92%;其中62.37%(58处)的压力性损伤为医疗设备相关,83.87%(78处)损伤程度为1期损伤;压力性损伤高发部位为鼻部[20.43%(19/93)],其次为骶尾部[17.20%(16/93)]、面颊[11.83%(11/93)]、枕部[10.75%(10/93)]、口部[9.68%(9/93)]、足跟部[7.53%(7/93)]、耳后[6.45%(6/93)]。入住NICU时间≥7 d(OR=3.025,95% CI:1.178~7.729)、机械通气(OR=4.568,95% CI:2.110~9.848)、意识昏迷(OR=4.397,95% CI:1.860~10.351)、嗜睡(OR=5.447,95% CI:2.359~12.578)和病情危重(OR=3.142,95% CI:1.184~8.340)是NICU患儿发生压力性损伤的独立危险因素。  结论  新生儿重症监护室主要以医疗设备相关性压力性损伤为主,高危诱发因素是多方面的,主要与患儿病情、活动受限、医疗设备使用有关。

     

  • 表  1  NICU患儿PI发生的单因素分析[例(%)]

    Table  1.   Univariate analysis of PI in children with NICU[cases(%)]

    项目 例数 发生PI(79例) 未发生PI(388例) χ2 P
    性别 0.481 0.488
        男 253 40(50.63) 213(54.90)
        女 214 39(49.37) 175(45.10)
    胎龄(周) 47.949 <0.001
        ≤37 67 31(39.24) 36(9.28)
        >37 400 48(60.76) 352(90.72)
    出生体重(kg) 6.497 0.011
        ≤1.5 69 19(24.05) 50(12.89)
        >1.5 398 60(75.95) 338(87.11)
    入院诊断 0.079 0.994
        神经系统疾病 115 19(24.05) 96(24.74)
        心血管系统疾病 107 19(24.05) 88(22.68)
        呼吸系统疾病 136 23(29.11) 113(29.12)
        消化系统疾病 109 18(22.78) 91(23.45)
    是否手术 30.213 <0.001
        是 71 28(35.44) 43(11.08)
        否 396 51(64.56) 345(88.92)
    入住NICU时间(d) 9.041 0.003
        ≥7 317 65(82.28) 252(64.95)
        <7 150 14(17.72) 136(35.05)
    病情严重程度 12.608 <0.001
        危重 183 45(56.96) 138(35.57)
        非危重 284 34(43.04) 250(64.43)
    意识状态 26.329 <0.001
        清醒 296 31(39.24) 265(68.30)
        嗜睡 92 22(27.85) 70(18.04)
        昏迷 79 26(32.91) 53(13.66)
    呼吸方式 19.391 <0.001
        机械通气 181 48(60.76) 133(34.28)
        自主呼吸 286 31(39.24) 255(65.72)
    下载: 导出CSV

    表  2  79例NICU患儿PI发生部位特征[处(%)]

    Table  2.   Location characteristics of PI in 79 NICU children[numbers(%)]

    部位 骨隆突处PI 医疗设备相关PI 总计
    头面部 8(8.60) 50(53.76) 58(62.37)
        枕部 7(7.53) 3(3.23) 10(10.75)
        前额 0 3(3.23) 3(3.23)
        面颊 0 11(11.83) 11(11.83)
        口部 0 9(9.68) 9(9.68)
        鼻部 0 19(20.43) 19(20.43)
        耳部 1(1.08) 5(5.38) 6(6.45)
    上肢 1(1.08) 2(2.15) 3(3.23)
        上臂 0 2(2.15) 2(2.15)
        肘部 1(1.08) 0 1(1.08)
    下肢 10(10.75) 2(2.15) 12(12.90)
        膝部 0 1(1.08) 1(1.08)
        足跟 6(6.45) 1(1.08) 7(7.53)
        足踝 4(4.30) 0 4(4.30)
    躯干 2(2.15) 2(2.15) 4(4.30)
        前胸 0 1(1.08) 1(1.08)
        背部 2(2.15) 1(1.08) 3(3.23)
    骶尾部 14(15.05) 2(2.15) 16(17.20)
    合计 35(37.63) 58(62.37) 93(100.00)
    下载: 导出CSV

    表  3  变量赋值方法

    Table  3.   Variable assignment method

    变量 赋值方法
    胎龄(周) ≤37=0;>37=1
    出生体重(kg) ≤1.5=0;>1.5=1
    是否手术 是=0;否=1
    入住NICU时间(d) ≥7=0;<7=2
    病情严重程度 危重=0;非危重=1
    意识状态 昏迷(1, 0);嗜睡(0, 1);清醒(0, 0)
    呼吸方式 机械通气=0;自主呼吸=1
    下载: 导出CSV

    表  4  NICU患儿PI发生的多因素logistic回归分析

    Table  4.   Multivariate logistic regression analysis of PI in children with NICU

    变量 B SE Wald χ2 P OR 95% CI
    胎龄≤37周 0.643 0.812 0.627 0.428 1.902 0.387~9.266
    出生体重≤1.5 kg 0.785 0.931 0.711 0.399 2.192 0.354~13.469
    手术 0.854 0.572 2.229 0.135 2.349 0.766~7.207
    入住NICU时间≥7 d 1.107 0.481 5.297 0.021 3.025 1.178~7.729
    病情危重 1.145 0.498 5.286 0.021 3.142 1.184~8.340
    昏迷 1.481 0.439 11.381 0.001 4.397 1.860~10.396
    嗜睡 1.695 0.427 15.757 <0.001 5.447 2.359~12.578
    机械通气 1.519 0.394 14.864 <0.001 4.568 2.110~9.887
    下载: 导出CSV
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出版历程
  • 收稿日期:  2021-09-15
  • 网络出版日期:  2022-11-30

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