复发性精神分裂症患者生活质量状况调查及影响因素分析

余林花; 王铁虎

doi:10.16766/j.cnki.issn.1674-4152.002463

复发性精神分裂症患者生活质量状况调查及影响因素分析

doi: 10.16766/j.cnki.issn.1674-4152.002463

余林花^1, ,,
王铁虎²

1.
杭州市第七人民医院浙江大学医学院精神卫生中心精神科，浙江杭州 310012
2.
湖州市第三人民医院精神科，浙江湖州 313000

基金项目:

浙江省医药卫生科技计划项目 2018KY787

详细信息

通讯作者:
余林花，E-mail：wllaigsdfo@163.com

中图分类号: R749.3
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- 文章访问数: 193
- HTML全文浏览量: 79
- PDF下载量: 0
- 被引次数: 0
出版历程
- 收稿日期: 2020-12-10
- 网络出版日期: 2022-09-05

Quality of life in patients with recurrent schizophrenia and analysis of influencing factors

YU Lin-hua^{1
, ,},
WANG Tie-hu²

1.
Department of Psychiatry, Hangzhou Seventh People's Hospital, Mental Health Center, Zhejiang University of Medicine, Hangzhou, Zhejiang 310012, China

摘要

摘要: 目的分析复发性精神分裂症患者的生活质量状况及影响因素。方法选取2017年2月—2020年2月在杭州市第七人民医院住院的复发性精神分裂症患者82例为研究对象，对患者的生活质量状况进行调查，并分析影响患者生活质量的相关因素。结果患者在生理、心理、社会关系和环境各领域的得分明显低于中国常模(均P < 0.01)。在生理和心理领域，初中及以下文化程度患者的得分明显低于高中及以上文化程度患者(均P < 0.05)；在社会关系领域，女性、无职业患者得分分别明显低于男性、有职业患者(均P < 0.05)；在环境领域，女性、无职业、初中及以下文化程度患者的得分分别明显低于男性、有职业、高中及以上文化程度的患者(均P < 0.05)。患者社会支持与生理领域、心理领域及环境领域呈正相关关系(均P < 0.05)，家庭关怀指数同各研究领域具有明显正相关性(P < 0.01)；服药依从性与生理和心理领域呈正相关关系(P < 0.01)。多元逐步回归分析显示性别、文化程度、社会支持、职业情况、家庭关怀指数、服药依从性是影响患者生活质量的主要因素(均P < 0.05)。结论复发性精神分裂症患者的生活质量低于常模水平，性别、家庭关怀指数、社会支持、文化程度、服药依从性、职业情况是影响患者生活质量的主要因素。
- 精神分裂症 /
- 复发性 /
- 生活质量 /
- 影响因素
Abstract: Objective To analyse the quality of life of patients with recurrent schizophrenia and its influencing factors. Methods A total of 82 patients with recurrent schizophrenia in Hangzhou Seventh People's Hospital from February 2017 to February 2020 were selected as the research subjects. The quality of life status of the patients and the related factors affecting the quality of life of the patients were investigated. Results Compared with the Chinese norm, the scores of the patients in physiological, psychological, social relationship and environment were significantly lower (all P < 0.01). In the fields of physiology and psychology, the scores of patients with junior high school education or below were significantly lower than those with senior high school education or above (all P < 0.05). In terms of social relationship, the scores of female and non-occupational patients were significantly lower than those of male and occupational patients (all P < 0.05). On the basis of the environment, the scores of females, non-occupational, junior high school or below education level were significantly lower than those of males, occupational, senior high school or above education level (all P < 0.05). The social support of patients was positively correlated with physiological field, psychological field and environmental field (all P < 0.05), and the family care index was significantly positively correlated with each research field (P < 0.01). Drug compliance was positively correlated with the physiological and psychological fields (P < 0.01). Multiple stepwise regression analysis showed that gender, education level, social support, occupation, family care index and medication compliance were the main factors affecting patients' quality of life (all P < 0.05). Conclusion Quality of life in patients with recurrent schizophrenia is below the norm. Gender, family care index, social support, education level, medication compliance and occupational status were the main factors affecting patients' quality of life.
- Schizophrenia /
- Recurrent /
- Quality of life /
- Influencing factor

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表 1 复发性精神分裂症患者生活质量现状(x±s，分)

Table 1. Quality of life in patients with recurrent schizophrenia(x±s)

组别	例数	生理领域	心理领域	社会关系领域	环境领域
复发性精神分裂症患者	82	50.65±11.27	51.21±12.75	46.85±14.23	47.26±11.28
中国常模		61.30±16.30	61.60±13.70	64.60±14.20	52.90±13.50
t值		-4.867	-5.027	-7.995	-2.903
P值		< 0.001	< 0.001	< 0.001	< 0.001

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表 2 影响复发性精神分裂症患者生活质量的单因素分析(x±s，分)

Table 2. Univariate analysis of quality of life in patients with recurrent schizophrenia (x±s, scores)

项目	例数	生理领域	心理领域	社会领域	环境领域
性别
男性	45	50.87±11.26	54.15±12.46	49.17±11.39	49.67±11.26
女性	37	50.26±11.31	48.29±12.78	43.98±11.21	41.38±11.23
t值		0.244	1.737	2.068	3.322
P值		0.808	0.086	0.042	0.001
年龄(岁)
< 45	53	51.29±11.32	51.05±12.75	47.27±12.65	47.63±12.96
≥45	29	50.02±11.82	51.67±12.72	46.78±12.81	47.01±12.85
t值		0.478	-0.211	0.167	0.208
P值		0.634	0.833	0.868	0.836
文化程度
初中及以下	47	47.15±11.16	46.18±11.76	45.18±11.38	43.28±11.47
高中及以上	35	53.65±12.79	53.67±12.89	47.79±12.82	51.72±11.86
t值		-2.449	-2.738	-0.973	-3.248
P值		0.016	0.008	0.333	0.002
婚姻状况
已婚	34	51.65±12.27	52.89±12.86	47.87±12.68	47.68±11.64
未婚或离异	48	49.87±11.69	50.48±13.79	45.86±12.85	47.13±11.61
t值		0.665	0.802	0.704	0.211
P值		0.508	0.425	0.483	0.833
生活成员
独居	25	49.37±12.46	51.76±12.72	45.27±12.86	45.26±12.68
与亲人生活	57	51.87±12.68	50.21±11.68	47.89±12.93	46.95±12.76
t值		-0.826	0.538	-0.853	-0.553
P值		0.411	0.592	0.396	0.582
职业情况
在职	31	51.64±11.75	52.26±12.72	49.63±12.87	48.71±12.38
无业	51	49.86±11.68	49.79±11.77	41.58±12.83	42.82±12.92
t值		0.668	0.894	2.752	2.033
P值		0.506	0.374	0.007	0.044

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表 3 患者生活质量与各领域的相关性(r值)

Table 3. Patients' quality of life and in all areas of relevance (r value)

项目	社会支持	家庭关怀指数	服药依从性
生理领域	0.376^a	0.528^b	0.402^b
心理领域	0.435^b	0.576^b	0.461^b
社会关系领域	0.213	0.837^b	0.129
环境领域	0.371^a	0.645^b	0.216
注：^aP < 0.05，^bP < 0.01。

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表 4 影响复发性精神分裂症患者生活质量的多因素分析

Table 4. Multivariate analysis of quality of life in patients with recurrent schizophrenia

项目	B	SE	β	t值	P值
生理领域
家庭关怀指数	2.602	1.034	0.365	2.513	0.016
社会支持	0.542	0.212	0.267	2.551	0.014
服药依从性	2.142	0.865	0.281	2.472	0.017
心理领域
文化程度	9.521	3.402	0.267	2.796	0.008
家庭关怀指数	2.487	1.057	0.275	2.362	0.023
服药依从性	2.448	0.885	0.252	2.757	0.008
社会支持	0.581	0.179	0.302	3.238	0.002
社会关系领域
性别	-8.792	3.095	-0.212	-2.837	0.007
职业情况	0.326	0.137	0.196	2.024	0.045
家庭关怀指数	6.486	0.802	0.718	8.097	< 0.001
环境领域
性别	-9.983	3.965	-0.272	-2.516	0.016
职业情况	2.147	0.863	0.283	2.471	0.017
家庭关怀指数	3.332	1.025	0.416	3.245	0.002
社会支持	0.431	0.214	0.239	2.021	0.045

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