子宫内膜息肉行宫腔镜联合天然孕激素治疗的效果观察

余平芝; 李菲菲

doi:10.16766/j.cnki.issn.1674-4152.002329

子宫内膜息肉行宫腔镜联合天然孕激素治疗的效果观察

doi: 10.16766/j.cnki.issn.1674-4152.002329

余平芝¹,
李菲菲^2, ,

1.
合肥市第三人民医院妇产科，安徽合肥 230022
2.
安徽医科大学基础医学院，安徽合肥 230031

基金项目:

安徽省教育厅重大研究项目 KJ2018ZD018

详细信息

通讯作者:
李菲菲, E-mail: 13965021937@163.com

中图分类号: R711.74 R713.4
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- 文章访问数: 479
- HTML全文浏览量: 146
- PDF下载量: 9
- 被引次数: 0
出版历程
- 收稿日期: 2021-08-15
- 网络出版日期: 2022-03-04

Clinical effect of endometrial polyps treated by hysteroscopic surgery combined with natural progesterone

YU Ping-zhi¹,
LI Fei-fei^{2
, ,}

1.
Department of Obstetrics and Gynecology, the Third People's Hospital of Hefei, Hefei, Anhui 230022, China

摘要

摘要: 目的探讨子宫内膜息肉行宫腔镜手术后再联合天然孕激素治疗的效果。方法选取合肥市第三人民医院2019年3月—2020年3月收治的70例子宫内膜息肉患者。按收治患者时间顺序分对照组和观察组，各35例。对照组行宫腔镜下子宫内膜息肉切除术，观察组行宫腔镜下子宫内膜息肉切除术后联合应用天然孕激素治疗。2组术后均予抗生素预防感染和止血、纠正贫血对症治疗。比较2组治疗效果，比较2组术后12个月复查时月经改善情况和子宫内膜息肉复发情况。结果 2组手术前平均血红蛋白值比较差异无统计学意义(P＞0.05)；术后12个月观察组平均血红蛋白值明显高于对照组, 差异有统计学意义(t=34.552, P＜0.001)；2组手术前平均经期比较差异无统计学意义(P＞0.05)；术后12个月观察组平均经期明显短于对照组, 差异有统计学意义(t=4.398，P＜0.001)。观察组术后12个月子宫内膜息肉复发5例(14.29%), 对照组术后12个月子宫内膜息肉复发21例(60.00%), 观察组复发率明显低于对照组(χ²=15.664，P＜0.001)。结论子宫内膜息肉行宫腔镜手术后联合天然孕激素治疗效果较好，优于单纯行宫腔镜下子宫内膜息肉切除术，值得妇科临床推广。
- 子宫内膜息肉 /
- 宫腔镜 /
- 天然孕激素 /
- 地屈孕酮片 /
- 月经 /
- 复发
Abstract: Objective To investigate the clinical effect of endometrial polyps treated by hysteroscopic surgery combined with natural progesterone. Methods Seventy cases of endometrial polyps admitted to the Third People's Hospital of Hefei from March 2019 to March 2020 were selected. According to the admitted time, they were divided into control group and observation group, with 35 cases in each group. The control group was treated with hysteroscopic endometrial polypectomy alone, and the observation group was treated with hysteroscopic endometrial polypectomy combined with natural progesterone. Both groups were treated with antibiotics to prevent infection, stop bleeding and correct anaemia. The therapeutic effect of the two groups was compared. The improvement of menstruation and the recurrence of endometrial polys were compared between the two groups at 12 months after surgery. Results No statistically significant difference in average haemoglobin value was found between the two groups before surgery (P > 0.05). At 12 months after surgery, the average haemoglobin value of the observation group was significantly higher than of the control group (t=34.552, P < 0.001). No statistically significant difference in average menstrual period was found between the two groups before surgery (P > 0.05). At 12 months after surgery, the average menstrual period of the observation group was significantly shorter than of the control group (t=4.398, P < 0.001). The recurrence rate of endometrial polyps 12 months after operation was 14.29% in the observation group and 60% in the control group. The recurrence rate of the observation group was significantly lower than that of the control group (χ²=15.664, P < 0.001). Conclusion The effect of hysteroscopic surgery combined with natural progesterone on endometrial polyps is better than that of hysteroscopic polypectomy alone. It is worthy of clinical promotion in gynaecology.
- Endometrial polyp /
- Hysteroscopy /
- Natural progesterone /
- Dydrogesterone /
- Menstruation /
- Recurrence

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表 1 2组患者手术前后血红蛋白(HB)量比较(x±s，g/L)

组别	例数	术前	术后12个月
对照组	35	83.36±3.72	90.30±3.25^a
观察组	35	84.25±2.73	110.70±1.28^a
t值		1.141	34.552
P值		0.258	＜0.001
注：与同组术前比较，^aP＜0.05。

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表 2 2组手术前后月经期比较(x±s，d)

组别	例数	术前	术后12个月
对照组	35	7.78±3.42	6.23±3.77^a
观察组	35	7.83±3.56	3.27±1.28^a
t值		0.060	4.398
P值		0.952	＜0.001
注：与同组术前比较，^aP＜0.05。

下载: 导出CSV

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