Abstract: Objective The pace of aging in our country is gradually accelerating, and the elderly with dementia has become an important burden to the society and family. The development of modern science and technology provides convenient conditions for the management of the mentally retarded elderly. This study aims to reduce the hidden danger of the safety of the mentally retarded elderly at home and improve their quality of life by establishing an information management platform for the mentally retarded elderly. Methods Forty cases of the elderly with dementia who met the criteria of case selection in Zhejiang Hospital from July to December 2018 were selected as the observation group, they were established a professional team and an information management platform to implement remote health management, 35 cases of the elderly with dementia who met the criteria of case selection in our hospital from January to June 2018 were selected as the control group, and they were given routine intervention, mainly through telephone follow-up or door-to-door service. After 6 months of intervention, QOL-AD was used to investigate the quality of life of the two groups of patients, and potential safety hazards in the two groups was counted. Results There was no significant difference in QOL-AD total score and mean score between the two groups(P>0.05).The total score and mean score of QOL-AD in the observation group were respectively 28.56±4.21 and 2.16±0.42, which were higher than 25.29±4.82 and 1.92±0.47 in the control group(t=3.136, 2.335, P=0.002, 0.022). The incidence of falls, falling to bed, loss and scald in the observation group was 40.0% lower than 68.6% in the control group, the difference was statistically significant(χ²=6.122, P=0.013). Conclusion Information management using modern technology platform can improve the medical experience of the elderly with dementia, improve the quality of life in home care for the elderly with dementia, reduce the occurrence of security risks, and has high application value.