Abstract: Objective To explore the effect of individualized Chinese medical nutrition nursing program on liver function, nutritional status and quality of life in patients with cirrhotic ascites and cacotrophy. Methods A total of 120 patients with cirrhotic ascites and cacotrophy admitted to our hospital from September 2017 to February 2018 were divided into observation group and control group according to different nursing methods. Both groups received nutritional risk screening on admission, the control group adopted the routine nutrition nursing measures, and the observation group adopted the individualized traditional Chinese medicine nutrition nursing program on the basis of the control group, and they were evaluated by nutritional risk screening before discharge. The improvement of liver function and nutritional status were observed in the two groups, and the quality of life, nursing satisfaction, the total score of nutrition risk in the two groups were compared. Results The serum albumin in the observation group was significantly higher than that in the control group, and the total number of abnormal bilirubin and aspartate aminotransferase was significantly lower than that of the control group, and the difference was statistically significant(all P<0.05); the skin-fold thickness of musculus triceps brachii, upper arm circumference and hemoglobin in the observation group were significantly higher than those in the control group, and the difference was statistically significant(all P<0.05); the scores of physiological function, physiological duty, physical pain, vitality, social function, emotional duty, mental health and general health in the observation group were significantly higher than those in the control group, and the differences were statistically significant(all P<0.05); the total satisfaction of the patients in the observation group was 95.00%, which was significantly higher than 81.67% in the control group, and the difference was statistically significant(P<0.05); the total score of nutrition risk before discharge in the observation group were significantly lower than that in the control group, and the differences were statistically significant(P<0.05). Conclusion The use of individualized traditional Chinese medicine nutrition nursing program for patients with cirrhotic ascites and cacotrophy can promote the effective recovery of liver function, and obviously improve the condition of cacotrophy in patients, the score of nutrition risk decreased, improve the quality of life and the patient's satisfaction with nursing, which is worthy of clinical application.