Abstract: Objective To investigate the risk factors and nursing strategies of bronchiectasis secondary pulmonary fungal infection. Methods A total of 74 patients with bronchodilator secondary pulmonary fungal infection in our hospital from March 2016 to April 2018 were selected as fungal infection group, and 118 patients with bronchiectasis non-common pulmonary fungal infection were selected as non-fungal infections group. The age, sex, combined basic lung disease, hospital time, diabetes, hypoproteinemia, respiratory failure, antibiotic using time, long-term use of glucocorticoids of two groups were accounted, and univariate and logistic regression analysis were used to investigate the risk factors. Results Univariate results showed that age, combined pulmonary basic disease, hospital time, diabetes, hypoproteinemia, antibiotic using time, respiratory failure, long-term use of glucocorticoids were the risk factors of patients with bronchiectasis secondary pulmonary fungal infection, and logistic regression analysis showed that age, combined pulmonary basic disease, hospital time, diabetes, hypoproteinemia, antibiotic using time, respiratory failure, long-term use of glucocorticoids were the risk factors of patients with bronchiectasis secondary pulmonary fungal infection. Conclusion Age, combined pulmonary basic disease, hospital time, diabetes, hypoproteinemia, antibiotic using time, respiratory failure, longterm use of glucocorticoids were the risk factors of patients with bronchiectasis secondary pulmonary fungal infection. So risk factors should receive attention, and treatment and nursing should be carried out to prevent fungal infections.