Abstract: Objective To investigate the effect of targeted nursing on restoration of pelvic floor exercises in elderly women with stress urinary incontinence (SUI). Methods The clinical data of 96 elderly female patients with SUI treated in our hospital from May, 2015 to June, 2017 were retrospectively analyzed. The patients were divided into the observation group and the control group with 48 cases in each group according to the different nursing methods. The control group was given routine care and the observation group was given with targeted nursing intervention on the basis of the control group. The 1h urine pad test, self efficacy score, ALPP, maximum urethral closure pressure and quality of life score were compared between the two groups before and 3 months after intervention. Results The result of 1 h urine pad test in two groups at 3 months after the intervention was significantly decreased compared with before intervention and the self-efficacy scores were significantly increased compared with before intervention(P<0.05). The decreased degree of 1 h urine pad test in observation group was significantly higher than that in the control group and the increased degree of self-efficacy scores in observation group was significantly higher than that in the control group (P<0.05). The ALPP and maximum urethral closure pressure in two groups at 3 months after the intervention were significantly increased compared with before intervention (P<0.05). The increased degree of ALPP and maximum urethral closure pressure in the observation group were significantly higher than that in the control group (P<0.05). Each dimension of physiology, psychology, environment and social relations and total score of quality of life in two groups at 3 months after the intervention were higher than that before the intervention (P<0.05). Each dimension of physiology, psychology, environment and social relations and total score of quality of life in observation groups were higher than that of control group (P<0.05). Conclusion Targeted nursing can effectively promote pelvic floor function recovery in elderly women with SUI, increase their compliance with exercise, and improve the symptoms and quality of life in patients with SUI.